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8.
J Clin Pathol ; 23(9): 781-3, 1970 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-5504372

RESUMO

A simple and rapid screening test which differentiates sickle-cell trait and sickle-cell anaemia is described. The test utilizes 0.1 ml of whole blood and is based on the low solubility of reduced sickle haemoglobin. Results intermediate between the sickle-cell trait and sickle-cell anaemia are obtained in unusual cases of sickle-cell anaemia with high foetal haemoglobin. The need to supplement the results with haematological and electrophoretic techniques is discusses.


Assuntos
Anemia Falciforme/diagnóstico , Hemoglobinometria , Humanos , Métodos , Solubilidade , Talassemia/diagnóstico
12.
Br Med J ; 4(5683): 595-6, 1969 Dec 06.
Artigo em Inglês | MEDLINE | ID: mdl-5356548

RESUMO

A survey for abnormal haemoglobins in Zambia has demonstrated Haemoglobin S-including 187 cases of sickle-cell anaemia, Haemoglobin J Oxford on one occasion, and a new Haemoglobin Zambia in four unrelated families. No evidence for beta-thalassaemia was found, but Haemoglobin H disease and other evidence for alpha-thalassaemia were found.


Assuntos
Asparagina/análise , Hemoglobinopatias/epidemiologia , Hemoglobinas Anormais/análise , Lisina/análise , Adulto , Anemia Falciforme/genética , Eletroforese das Proteínas Sanguíneas , Humanos , Lactente , Talassemia/genética , Zâmbia
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