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Mater Sci Eng C Mater Biol Appl ; 44: 38-43, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25280677

RESUMO

The development of bioactive materials is in the premise of tissue engineering. For several years, surface functionalization of scaffolds has been one of the most promising approaches to stimulate cellular activity and finally improve implant success. Herein, we describe the development of a bioactive composite scaffold composed of a biodegradable photopolymer scaffold and titanate nanotubes (TNTs). The biodegradable photopolymer scaffolds were fabricated by applying mask-projection excimer laser photocuring at 308 nm. TNTs were synthesized and then spin-coated on the porous scaffolds. Upon culturing fibroblast cells on scaffolds, we found that nanotubes coating affects cell viability and proliferation demonstrating that TNT coatings enhance cell growth on the scaffolds by further improving their surface topography.


Assuntos
Materiais Revestidos Biocompatíveis/química , Nanotubos/química , Polímeros/química , Alicerces Teciduais/química , Titânio/química , Células 3T3 , Animais , Proliferação de Células/efeitos dos fármacos , Sobrevivência Celular/efeitos dos fármacos , Células Cultivadas , Camundongos , Microscopia Eletrônica de Transmissão , Porosidade , Engenharia Tecidual
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