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4.
Med Radiol (Mosk) ; 29(3): 30-5, 1984 Mar.
Artigo em Russo | MEDLINE | ID: mdl-6321882

RESUMO

In 116 patients with coronary heart disease, essential hypertension, acute and chronic glomerulonephritis and pyelonephritis, the authors observed differences in the excretion of the ions of 42K, stable potassium, 24Na, stable sodium, chlorine as well as in the value of diuresis during the administration of equimolar solutions of potassium hydrocarbonate and potassium chloride, sodium hydrocarbonate and sodium chloride labeled with 42K and 24Na respectively. These differences depended on the expression of the basic (alkaline) characteristics of the anions of the administered solutions of potassium and sodium and the osmolarity of the administered amount of liquid. Pronounced ion exchange reactions were observed during the administration of KHCO3 solution only, the multiplicity factor of the excretion of sodium and chlorine ions with urine significantly exceeding that of diuresis. During the administration of KCl solutions in the isotonic NaCl solution and 5% glucose, the excretion of sodium and chlorine ions changed strictly in accordance with the changes of diuresis. Similar changes were noted in the administration of the solutions of sodium hydrocarbonate and sodium chloride.


Assuntos
Doença das Coronárias/metabolismo , Hipertensão/metabolismo , Compostos de Potássio , Potássio/metabolismo , Sódio/metabolismo , Bicarbonatos/administração & dosagem , Humanos , Injeções Intravenosas , Cloreto de Potássio/administração & dosagem , Radioisótopos de Potássio , Bicarbonato de Sódio , Cloreto de Sódio/administração & dosagem , Radioisótopos de Sódio , Soluções
7.
Kosm Biol Aviakosm Med ; 15(1): 61-2, 1981.
Artigo em Russo | MEDLINE | ID: mdl-7218752

RESUMO

The paper describes accelerations affecting men working aboard the ship of 22,000 tons displacement in stormy weather.


Assuntos
Aceleração , Enjoo devido ao Movimento/etiologia , Medicina Naval , Tempo (Meteorologia) , Força Coriolis , Humanos , Navios , Vento
13.
Farmakol Toksikol ; 39(2): 230-2, 1976.
Artigo em Russo | MEDLINE | ID: mdl-1278358

RESUMO

The potassium hydrocarbonate and potassium chloride toxicity was compared in experiments on 113 albino rats. The death following introduction of maximal amounts of potassium chloride was noted to supervene earlier than it did in animals receiving equivalent doses of potassium hydrocarbonate. Simultaneous introduction of sodium hydrocarbonate lowered the toxicity of both potassium hydrocarbonate and chloride. Morphological investigations revealed that toxic doses of potassium hydrocarbonate bring about shifts in the carbohydrate and lipids metabolism. Some mechanisms behind the action produced potassium chloride and hydrocarbonate are discussed.


Assuntos
Cloreto de Potássio/toxicidade , Potássio/toxicidade , Animais , Comportamento Animal/efeitos dos fármacos , Peso Corporal/efeitos dos fármacos , Carbonatos/toxicidade , Relação Dose-Resposta a Droga , Interações Medicamentosas , Eletrocardiografia , Coração/efeitos dos fármacos , Ratos , Sódio/farmacologia
15.
Farmakol Toksikol ; 38(6): 734-7, 1975.
Artigo em Russo | MEDLINE | ID: mdl-1227926

RESUMO

The toxicity of potassium hydrocarbonate and chloride was compared in tests on 113 albino rats. It was noted that following introduction of maximal amounts of potassium chloride death occurred earlier in these animals than in the ones which received equivalent doses of potassium hydrocarbonate. Simultaneous administration of sodium hydrocarbonate reduced the toxicity of potassium hydrocarbonate and potassium chloride. Morphological investigations brought out that toxic doses of potassium hydrocarbonate led to shifts of the carbohydrate and lipids metabolism. Some mechanisms underlying the action of potassium chloride and potassium hydrocarbonate are discussed.


Assuntos
Carbonatos/toxicidade , Cloreto de Potássio/toxicidade , Potássio/toxicidade , Animais , Comportamento Animal/efeitos dos fármacos , Peso Corporal , Tolerância a Medicamentos , Eletrocardiografia , Masculino , Ratos , Sódio/toxicidade , Cloreto de Sódio/toxicidade , Soluções
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