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1.
Arch Ital Urol Androl ; 84(4): 276-8, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23427763

RESUMO

Pancake kidney is a very rare fusion abnormality, characterised by the presence of a renal parenchymal mass located in pelvic site, generally with two pelvies and two ureters and without an intervening fibrous septum. The case here reported describes a condition of "pancake kidney", eventually associated with polycystic disease and abnormous vascular supply. Hypertension and microscopic hematuria were the only clinical signs.


Assuntos
Rim/anormalidades , Doenças Renais Policísticas/complicações , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Renais Policísticas/diagnóstico
2.
Nephrol Dial Transplant ; 24(10): 3103-7, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19549691

RESUMO

INTRODUCTION: Intravenous administration of saline and non-ionic isosmolar contrast media significantly reduces the incidence of contrast-induced nephropathy, one of the most common causes of acute renal failure. Results with oral N-acetylcysteine are conflicting. The aim of our study was to evaluate the prophylactic role of N-acetylcysteine in patients with stable chronic renal failure undergoing coronary and/or peripheral angiography and/or angioplasty. METHODS: We randomized 200 elective, consecutive patients (mean age 74.9 +/- 7.3 years; 65% male, 25% diabetics) with basal creatinine clearance 0.5 mg/dl or >25% within 3 days after the procedure. Serum creatinine was measured at baseline, 24, 48 and 72 h after the procedure. RESULTS: Contrast-induced nephropathy was 8/99 (8.1%) in the N-acetylcysteine group versus 6/101 (5.9%) in the placebo group, P = 0.6. No difference was noted in high-risk subgroups such as diabetics (4/25 versus 2/25 P = 0.4) and those with serum creatinine clearance <42.3 ml/min (5/54 versus 4/48; P = 0.9). CONCLUSION: In our experience, N-acetylcysteine did not prevent contrast-induced nephropathy in patients receiving isosmolar (iodixanol) contrast media and adequate hydration.


Assuntos
Acetilcisteína/uso terapêutico , Meios de Contraste/efeitos adversos , Sequestradores de Radicais Livres/uso terapêutico , Nefropatias/induzido quimicamente , Nefropatias/prevenção & controle , Falência Renal Crônica , Idoso , Feminino , Humanos , Masculino , Concentração Osmolar , Estudos Prospectivos
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