Neumomediastino espontáneo / Spontaneous pneumomediastinum

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Tuberculosis pancreática primaria en un paciente inmunocompetente: primer caso comunicado en España / Primary pancreatic tuberculosis in an immunocompetent patient: first case report in Spain

La tuberculosis pancreática primaria (TBPP) es una entidad excepcional definida por una lesión aislada del páncreas con confirmación microbiológica, en ausencia de TB conocida y sin afectación a ningún otro nivel. Se presenta el caso de un varón de 47 años con dolor abdominal y síndrome constitucional, diagnosticado mediante técnicas de imagen de masa sólida localmente avanzada en la cabeza del páncreas. La PAAF detectó granulomas necróticos. La prueba de la tuberculina intradérmica fue positiva. La tinción para bacilos ácido-alcohol resistentes del material de la 2.a PAAF fue negativa. No se encuentra TB tras un exhaustivo estudio diagnóstico. Se plantea laparotomía exploradora, pero a los 50 días crece Mycobacterium tuberculosis en el cultivo. La lesión pancreática desapareció tras 4 meses de tratamiento antituberculostático. Este es el primer caso descrito en España de TBPP en inmunocompetentes. Su diagnóstico exige una elevada sospecha y muestras óptimas microbiológicas para evitar cirugías innecesarias (AU)

Primary pancreatic tuberculosis (PPTB) is an extremely rare entity defined by an isolated pancreatic lesion with microbiological confirmation, in the absence of previously identified tuberculosis (TB) and involvement of any other organ. We report the case of a 47-year-old man referred for abdominal pain and weight loss, in whom several imaging techniques revealed a solid mass in the head of the pancreas. CT-guided fine-needle aspiration cytology was consistent with necrotic granuloma. Intradermic tuberculin reaction was positive, but acid fast bacilli staining was negative in repeat cytology. No additional evidence of TB was found after exhaustive diagnostic work-up. Exploratory laparotomy was proposed for a definitive diagnosis, but cultures grew Mycobacterium tuberculosis at 50 days. The pancreatic lesion disappeared after 4 months of antitubercular therapy. This is the first case report of PPTB in an immunocompetent person in Spain. A high index of suspicion and accurate samples for microbiology are mandatory to avoid unnecessary surgical procedures (AU)

[Primary pancreatic tuberculosis in an immunocompetent patient: first case report in Spain]. / Tuberculosis pancreática primaria en un paciente inmunocompetente: primer caso comunicado en España.

Primary pancreatic tuberculosis (PPTB) is an extremely rare entity defined by an isolated pancreatic lesion with microbiological confirmation, in the absence of previously identified tuberculosis (TB) and involvement of any other organ. We report the case of a 47-year-old man referred for abdominal pain and weight loss, in whom several imaging techniques revealed a solid mass in the head of the pancreas. CT-guided fine-needle aspiration cytology was consistent with necrotic granuloma. Intradermic tuberculin reaction was positive, but acid fast bacilli staining was negative in repeat cytology. No additional evidence of TB was found after exhaustive diagnostic work-up. Exploratory laparotomy was proposed for a definitive diagnosis, but cultures grew Mycobacterium tuberculosis at 50 days. The pancreatic lesion disappeared after 4 months of antitubercular therapy. This is the first case report of PPTB in an immunocompetent person in Spain. A high index of suspicion and accurate samples for microbiology are mandatory to avoid unnecessary surgical procedures.