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Drug News Perspect ; 22(1): 7-29, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19209296

RESUMO

This annual article presents new drugs and biologics that were launched or approved for the first time during the previous year. In 2008, 31 new medicines-this figure includes both drugs and biologics for therapeutic use as well as new diagnostic agents-reached their first markets. Line extensions (new indications, new formulations and new combinations of previously marketed products) accounted for more than one-third of the new medicines launched in 2008. In addition to providing an overview of all drugs and biologics launched or approved for the first time ever in the previous year, this article will also review in further depth the first-in-class drugs launched for the first time last year, providing a better understanding of their novel mechanisms of action; an analysis of the discovery and development periods for the year's new products; and a comprehensive overview of drug repositioning as a strategy for extending the life spans of medicines. We also provide a brief glimpse at selected drugs and biologics which could reach their first markets in the foreseeable future.


Assuntos
Produtos Biológicos , Aprovação de Drogas , Preparações Farmacêuticas , Desenho de Fármacos , Indústria Farmacêutica/tendências , Humanos
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