RESUMO
Ovine contagious foot rot may cause lameness in sheep, resulting in decreased wool growth and low weight gain. Affected neonatal lambs are difficult to treat, and treatment is labor intensive; thus, a method of prevention is warranted. Vaccination of ewes with a multivalent vaccine in an oil adjuvant induced development of antibody to the somatic O antigen of Bacteroides nodosus, and this antibody was detected in serum of newborn lambs after consumption of colostrum from the vaccinated ewes. Antibody titers were determined in 48 unvaccinated ewe/lamb pairs, and in 50 once-vaccinated and 78 twice-vaccinated pairs. Serum and colostrum O-agglutinin titers to B nodosus were determined by a microtitration agglutination test. Lambs from vaccinated ewes had significantly (P less than 0.05) higher O-agglutinin titers than those from unvaccinated ewes, and double vaccination of ewes resulted in the highest potentially protective titers (greater than 1:2,400) in ewes and lambs.
Assuntos
Vacinas Bacterianas , Bacteroides/imunologia , Pododermatite Necrótica dos Ovinos/imunologia , Imunidade Materno-Adquirida , Doenças dos Ovinos/imunologia , Testes de Aglutinação , Animais , Animais Recém-Nascidos , Anticorpos Antibacterianos/análise , Anticorpos Antibacterianos/sangue , Colostro/imunologia , Feminino , Pododermatite Necrótica dos Ovinos/prevenção & controle , Imunoglobulinas/análise , Imunoglobulinas/sangue , Gravidez , Análise de Regressão , Ovinos , Doenças dos Ovinos/prevenção & controle , Vacinação/métodos , Vacinação/veterináriaRESUMO
Bacterial endocarditis of the tricuspid valve was diagnosed in a cow with weight loss, reduced milk production, and intermittent fever. Clinical signs of disease included jugular and mammary vein pulses, tachycardia, large cardiac silhouette, and grade-III/V holosystolic murmur. The diagnosis was also supported by echocardiographic findings and isolation of Streptococcus viridans from blood samples. The cow was treated with penicillin, furosemide, acetylsalicylic acid, heparin, and potassium chloride and survived 14 months after the diagnosis, producing 1 live calf and 4 viable embryos. The cow's heart rate exceeded an upper normal limit of 80 beats/min during most of the initial 4 months of treatment. Additional clinical signs of disease that were observed during treatment included diarrhea, ventral edema, and coughing. General medicine and cardiology textbooks have previously minimized the potential benefits of anticoagulant use in cases of septic endocarditis. The advent of routinely performed embryo transfer procedures may make treatment of endocarditis feasible in cattle with exceptional genetic merit.
Assuntos
Doenças dos Bovinos/diagnóstico , Endocardite Bacteriana/veterinária , Complicações Infecciosas na Gravidez/veterinária , Infecções Estreptocócicas/veterinária , Animais , Temperatura Corporal , Bovinos , Doenças dos Bovinos/tratamento farmacológico , Transferência Embrionária/veterinária , Endocardite Bacteriana/diagnóstico , Endocardite Bacteriana/tratamento farmacológico , Feminino , Penicilina G Procaína/uso terapêutico , Gravidez , Complicações Infecciosas na Gravidez/diagnóstico , Complicações Infecciosas na Gravidez/tratamento farmacológico , Infecções Estreptocócicas/diagnóstico , Infecções Estreptocócicas/tratamento farmacológicoRESUMO
Combined immunodeficiency was documented in a 6-week-old Angus calf. The calf had lymphopenia, undetectable serum IgM or IgA, and low concentrations of serum IgG (420 mg/dl). The calf was treated for diarrhea, pneumonia, and shock, and was given antimicrobial drugs, fluids, and plasma. The calf died of systemic candidiasis and Escherichia coli bacteremia. Aggregated lymphatic folliculi (Peyer patches), lymph nodes, and thymic and splenic lymphoid tissue could not be identified at necropsy.