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2.
Cardiol Young ; 30(7): 919-922, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32498738

RESUMO

Idiopathic dilatation of the right atrium is an isolated enlargement of the right atrium in the absence of other cardiac lesions. This rare anomaly has a clinical spectrum ranging from asymptomatic to heart failure or even sudden death. It can be associated with atrial arrhythmias and thrombus formation. Antiplatelet therapy is prescribed in most cases reported in the literature, and reduction plasty is indicated when there is rapid growth of the right atrium, compression of adjacent structures, or refractory arrhythmias. We report four cases of idiopathic dilatation of the right atrium diagnosed during prenatal screening. We describe the intrauterine course and management in postnatal life until early childhood.


Assuntos
Aneurisma , Átrios do Coração , Arritmias Cardíacas , Pré-Escolar , Dilatação , Dilatação Patológica , Feminino , Átrios do Coração/diagnóstico por imagem , Humanos , Gravidez
3.
Pediatr Cardiol ; 41(4): 687-694, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31919591

RESUMO

To improve the understanding of the pathophysiology of transposition of the great arteries with intact ventricular septum (TGA/IVS) and the cardiac remodeling occurring from fetal to neonatal life, we performed a morphometric and functional echocardiographic assessment in fetuses and newborns. This was a prospective case-control study performed in a tertiary referral center, which included fetuses and newborns with a diagnosis of TGA/IVS between 2011 and 2018. Morphometry and systolic and diastolic function parameters were compared with age and body surface-matched healthy controls. Twenty-one TGA/IVS patients were included during the study period and morphometric and functional echocardiographic data were recorded. TGA/IVS patients showed morphometric and functional changes of increased overall volume and output, predominantly in the aortic component from fetus to newborn, probably due to compensatory mechanisms secondary to brain hypoxia.


Assuntos
Ecocardiografia/métodos , Transposição dos Grandes Vasos/diagnóstico por imagem , Septo Interventricular/diagnóstico por imagem , Estudos de Casos e Controles , Feminino , Coração Fetal/diagnóstico por imagem , Idade Gestacional , Humanos , Recém-Nascido , Masculino , Estudos Prospectivos , Transposição dos Grandes Vasos/fisiopatologia
4.
Cardiol Young ; 28(2): 284-291, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29081323

RESUMO

Introduction The adaptive changes of the foetal heart in intrauterine growth restriction can persist postnatally. Data regarding its consequences for early circulatory adaptation to extrauterine life are scarce. The aim of this study was to assess cardiac morphometry and function in newborns with late-onset intrauterine growth restriction to test the hypothesis that intrauterine growth restriction causes cardiac shape and functional changes at birth. METHODS: A comprehensive echocardiographic study was performed in 25 neonates with intrauterine growth restriction and 25 adequate-for-gestational-age neonates. RESULTS: Compared with controls, neonates with intrauterine growth restriction had more globular ventricles, lower longitudinal tricuspid annular motion, and higher left stroke volume without differences in the heart rate. Neonates with intrauterine growth restriction also showed subclinical signs of diastolic dysfunction in the tissue Doppler imaging with lower values of early (e') diastolic annular peak velocities in the septal annulus. Finally, the Tei index in the tricuspid annulus was higher in the intrauterine growth restriction group. CONCLUSION: Neonates with history of intrauterine growth restriction showed cardiac remodelling and signs of systolic and diastolic dysfunction. Overall, there was a significant tendency to worse cardiac function results in the right heart. The adaptation to extrauterine life occurred with more globular hearts, higher stroke volumes but a similar heart rate compared to adequate-for-gestational-age neonates.


Assuntos
Ecocardiografia Doppler/métodos , Retardo do Crescimento Fetal/diagnóstico , Coração Fetal/diagnóstico por imagem , Ventrículos do Coração/diagnóstico por imagem , Complicações Cardiovasculares na Gravidez/diagnóstico , Ultrassonografia Pré-Natal/métodos , Função Ventricular Esquerda/fisiologia , Adulto , Feminino , Retardo do Crescimento Fetal/fisiopatologia , Coração Fetal/fisiopatologia , Seguimentos , Idade Gestacional , Ventrículos do Coração/embriologia , Ventrículos do Coração/fisiopatologia , Humanos , Recém-Nascido , Masculino , Gravidez , Estudos Prospectivos , Volume Sistólico , Sístole
5.
Fetal Diagn Ther ; 39(2): 90-9, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26113195

RESUMO

OBJECTIVES: To report on the accuracy of fetal echocardiography in the distinction between truncus arteriosus communis (CAT) and pulmonary atresia with ventricular septal defect (PA-VSD) and to describe the association with extracardiac and chromosomal anomalies. METHODS: This was a retrospective study on 31 fetuses with a single arterial trunk overriding a VSD with a nonidentifiable right ventricle outflow tract with anterograde flow. Data on the type of cardiac defect, gestational age, characteristics of the arterial trunk valve, presence of additional vascular, chromosomal and extracardiac abnormalities and postnatal outcome were obtained. Misdiagnosed cases were reevaluated by four-dimensional spatiotemporal image correlation (4D-STIC) echocardiography. RESULTS: The overall diagnostic accuracy was 81% and increased to 93.5% with 4D-STIC. Chromosomal and extracardiac anomalies were detected in 40 and 27%, respectively. In the PA-VSD group, patent ductus arteriosus and major aortopulmonary collateral arteries (MAPCAs) were present in 70 and 50% of the cases, respectively, coexisting in 1 of 5 cases. MAPCAs were significantly associated with a right aortic arch and with a 22q11 microdeletion in 50% of cases. CONCLUSIONS: A prenatal distinction between CAT and PA-VSD can currently be achieved in most cases. MAPCAs should be actively searched for when PA-VSD is suspected, as they are associated with a higher risk of 22q11 microdeletion and potentially complicate postnatal treatment.


Assuntos
Ecocardiografia , Comunicação Interventricular/diagnóstico por imagem , Diagnóstico Pré-Natal/métodos , Atresia Pulmonar/diagnóstico por imagem , Tronco Arterial/diagnóstico por imagem , Diagnóstico Diferencial , Humanos , Prognóstico , Estudos Retrospectivos
6.
Circulation ; 128(13): 1442-50, 2013 Sep 24.
Artigo em Inglês | MEDLINE | ID: mdl-23985787

RESUMO

BACKGROUND: Assisted reproductive technologies (ARTs) have been shown to be associated with general vascular dysfunction in late childhood. However, it is unknown whether cardiac remodeling is also present and if these changes already manifest in prenatal life. Our aim was to assess fetal and infant (6 months of age) cardiovascular function in ART pregnancies. METHODS AND RESULTS: This prospective cohort study included 100 fetuses conceived by ART and 100 control pregnancies. ART fetuses showed signs of cardiovascular remodeling, including a more globular heart with thicker myocardial walls, decreased longitudinal function (tricuspid ring displacement in controls: median, 6.5 mm [interquartile range, 6.1-7.1 mm]; tricuspid ring displacement in ART: 5.5 mm [interquartile range, 5.1-6.1]; P<0.001), impaired relaxation, and dilated atria (atrial area in controls, 1.46 cm(2) [interquartile range, 1.2-1.5 cm(2)]; atrial area in ART, 1.6 cm(2) [interquartile range, 1.3-1.8 cm(2)]; P<0.001). Additionally, ART infants showed persistence of most cardiac changes and a significant increase in blood pressure and aortic intima-media thickness (systolic blood pressure in controls, 74 mm Hg [interquartile range, 67-83 mm Hg]; systolic blood pressure in ART, 83 mm Hg [interquartile range, 75-94 mm Hg]; P<0.001; aortic intima-media thickness in controls, 0.52 mm [interquartile range, 0.45-0.56 mm]; aortic intima-media thickness in ART, 0.64 mm [interquartile range, 0.62-0.67]; P<0.001). We could not demonstrate that our findings were directly caused by ART because of their association with various confounding factors, including intrauterine growth restriction or factors related to the cause of infertility. CONCLUSIONS: Children conceived by ART manifest cardiac and vascular remodeling that is present in fetal life and persists in postnatal life, suggesting opportunities for early detection and potential intervention. The underlying mechanisms and the effect of potential confounders such as growth restriction or prematurity remain to be elucidated.


Assuntos
Coração Fetal/diagnóstico por imagem , Coração Fetal/fisiologia , Recém-Nascido/fisiologia , Técnicas de Reprodução Assistida/efeitos adversos , Remodelação Ventricular/fisiologia , Adulto , Estudos de Coortes , Feminino , Seguimentos , Humanos , Lactente , Masculino , Gravidez , Estudos Prospectivos , Técnicas de Reprodução Assistida/tendências , Ultrassonografia
7.
Am J Obstet Gynecol ; 207(2): 121.e1-9, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22717268

RESUMO

OBJECTIVE: The objective of the study was to evaluate cardiovascular function in children who were small-for-gestational-age (SGA) fetuses. STUDY DESIGN: This was a prospective study including 100 controls and 50 children diagnosed in utero as SGA after 34 weeks subdivided into the following categories: SGA and intrauterine growth restriction (IUGR) according to the absence or presence, respectively, of weight centile less than 3 or abnormal cerebroplacental Doppler. Postnatal cardiovascular outcome was evaluated at 3-6 years of age by echocardiography, blood pressure, and carotid ultrasound. RESULTS: Both SGA and IUGR presented in childhood more globular hearts, reduced longitudinal motion, and impaired relaxation with an increase in radial function. Both groups showed increased blood pressure and carotid intima-media thickness. There was a linear tendency to worse cardiovascular results in IUGR as compared with SGA. CONCLUSION: Fetal cardiovascular programming occurs in SGA, regardless of Doppler and weight centile. These findings challenge the concept of constitutionally small and warrant further investigation to identify predictors of cardiovascular outcome in SGA.


Assuntos
Pressão Sanguínea , Artérias Carótidas/diagnóstico por imagem , Ecocardiografia , Retardo do Crescimento Fetal/diagnóstico por imagem , Recém-Nascido Pequeno para a Idade Gestacional , Túnica Média/diagnóstico por imagem , Débito Cardíaco , Estudos de Casos e Controles , Criança , Pré-Escolar , Feminino , Frequência Cardíaca , Ventrículos do Coração/diagnóstico por imagem , Humanos , Recém-Nascido , Masculino , Gravidez , Estudos Prospectivos , Índice de Gravidade de Doença , Volume Sistólico , Ultrassonografia Doppler , Ultrassonografia Pré-Natal
8.
Circulation ; 124(18): 1919-26, 2011 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-21986286

RESUMO

BACKGROUND: Isolated complete atrioventricular block in the fetus is a rare but potentially lethal condition in which the effect of steroid treatment on outcome is unclear. The objective of this work was to study risk factors associated with death and the influence of steroid treatment on outcome. METHODS AND RESULTS: We studied 175 fetuses diagnosed with second- or third-degree atrioventricular block (2000-2007) retrospectively in a multinational, multicenter setting. In 80% of 162 pregnancies with documented antibody status, atrioventricular block was associated with maternal anti-Ro/SSA antibodies. Sixty-seven cases (38%) were treated with fluorinated corticosteroids for a median of 10 weeks (1-21 weeks). Ninety-one percent were alive at birth, and survival in the neonatal period was 93%, similar in steroid-treated and untreated fetuses, regardless of degree of block and/or presence of anti-Ro/SSA. Variables associated with death were gestational age < 20 weeks, ventricular rate ≤ 50 bpm, fetal hydrops, and impaired left ventricular function at diagnosis. The presence of ≥ 1 of these variables was associated with a 10-fold increase in mortality before birth and a 6-fold increase in the neonatal period independently of treatment. Except for a lower gestational age at diagnosis in treated than untreated (23.4 ± 2.9 versus 24.9 ± 4.9 weeks; P=0.02), risk factors were distributed equally between treatment groups. Two-thirds of survivors had a pacemaker by 1 year of age; 8 children developed cardiomyopathy. CONCLUSIONS: Risk factors associated with a poor outcome were gestation < 20 weeks, ventricular rate ≤ 50 bpm, hydrops, and impaired left ventricular function. No significant effect of treatment with fluorinated corticosteroids was seen.


Assuntos
Bloqueio Atrioventricular/mortalidade , Morte Fetal/epidemiologia , Doenças Fetais/mortalidade , Adulto , Anticorpos Antinucleares/sangue , Bloqueio Atrioventricular/tratamento farmacológico , Bloqueio Atrioventricular/imunologia , Feminino , Doenças Fetais/tratamento farmacológico , Doenças Fetais/imunologia , Idade Gestacional , Humanos , Recém-Nascido , Plasmaferese , Gravidez , Resultado da Gravidez/epidemiologia , Estudos Retrospectivos , Fatores de Risco , Esteroides/uso terapêutico , Adulto Jovem
9.
Rev. esp. cardiol. (Ed. impr.) ; 64(9): 780-787, sept. 2011. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-90867

RESUMO

Introducción y objetivos. El objetivo es analizar la utilidad de la prueba de esfuerzo con determinación de gases espirados en niños operados de cardiopatía congénita en edad escolar, para valorar la recomendación de ejercicio físico en relación con la cardiopatía de base, el tipo de cirugía realizada, la situación hemodinámica actual y el nivel de ejercicio habitual. Métodos. Estudio prospectivo de 108 niños que realizaron una prueba de esfuerzo con análisis de gases, monitorizando electrocardiograma y presión arterial. Se recogieron por cuestionario variables sobre cardiopatía de base, cirugía practicada, estado funcional actual y nivel de ejercicio habitual. Se emitió una recomendación de ejercicio después de la ergometría, y al año se controló por cuestionario a 35 de los pacientes. Resultados. Se observaron diferencias significativas entre la gravedad actual de la lesión y la frecuencia cardiaca de reposo y esfuerzo, la presión arterial sistólica en reposo y en esfuerzo, el consumo de oxígeno, el pulso de oxígeno, la producción de dióxido de carbono y la duración de la prueba. Se detectó relación entre el nivel de ejercicio semanal y mayores consumo de oxígeno y duración de la ergometría, pero no con la cardiopatía subyacente. En los 59 niños con lesiones cianóticas, se observó que la mejor capacidad funcional se correspondía con reparación de la lesión más precoz y mejor. Se pudo recomendar un incremento del nivel de ejercicio a 48 niños. Conclusiones. La prueba ergoespirométrica permite explorar la capacidad funcional de los niños operados de cardiopatía congénita y aporta datos importantes para una mejor planificación del ejercicio físico aconsejable (AU)


Introduction and objectives. To analyze and discover if stress testing with exhaled gases in children who have had congenital heart surgery is useful so we could make physical exercise recommendations according to heart disease, type of surgery performed, present hemodynamic state and level of exercise practiced. Methods. Prospective study of 108 children, who performed stress testing with exhaled gases, electrocardiogram monitoring and blood pressure. A questionnaire was used to obtain variables concerning heart disease, surgery, present functional condition and level of exercise practiced. Exercise recommendations were given after stress testing, and after a year 35 patients answered a questionnaire. Results. There were significant differences between lesion severity and heart rate at rest and during effort, systolic pressure at rest and during effort, oxygen uptake, oxygen pulse, carbon dioxide production and test duration. A relationship was observed between level of weekly exercise and greater oxygen uptake and test duration, but this was not observed with the underlying heart disease. We observed that best performance occurred with fast repairing for 59 children with cyanotic heart disease. Increased exercise level was recommended for 48 children. Conclusions. The cardiopulmonary function study allows us to examine the physical performance of children who have had congenital heart surgery and provides us with important data so that we can recommend better physical exercise planning (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Teste de Esforço/métodos , Cardiopatias Congênitas/fisiopatologia , Cardiopatias Congênitas/reabilitação , Cardiopatias Congênitas/cirurgia , Exercício Físico , Teste de Esforço/tendências , Teste de Esforço , Estudos Prospectivos , Inquéritos e Questionários , Ergometria , Frequência Cardíaca/fisiologia , Análise Multivariada
10.
Rev Esp Cardiol ; 64(9): 780-7, 2011 Sep.
Artigo em Espanhol | MEDLINE | ID: mdl-21775042

RESUMO

INTRODUCTION AND OBJECTIVES: To analyze and discover if stress testing with exhaled gases in children who have had congenital heart surgery is useful so we could make physical exercise recommendations according to heart disease, type of surgery performed, present hemodynamic state and level of exercise practiced. METHODS: Prospective study of 108 children, who performed stress testing with exhaled gases, electrocardiogram monitoring and blood pressure. A questionnaire was used to obtain variables concerning heart disease, surgery, present functional condition and level of exercise practiced. Exercise recommendations were given after stress testing, and after a year 35 patients answered a questionnaire. RESULTS: There were significant differences between lesion severity and heart rate at rest and during effort, systolic pressure at rest and during effort, oxygen uptake, oxygen pulse, carbon dioxide production and test duration. A relationship was observed between level of weekly exercise and greater oxygen uptake and test duration, but this was not observed with the underlying heart disease. We observed that best performance occurred with fast repairing for 59 children with cyanotic heart disease. Increased exercise level was recommended for 48 children. CONCLUSIONS: The cardiopulmonary function study allows us to examine the physical performance of children who have had congenital heart surgery and provides us with important data so that we can recommend better physical exercise planning.


Assuntos
Procedimentos Cirúrgicos Cardíacos , Teste de Esforço/métodos , Exercício Físico , Cardiopatias Congênitas/fisiopatologia , Cardiopatias Congênitas/cirurgia , Análise de Variância , Pressão Sanguínea , Dióxido de Carbono/metabolismo , Criança , Cianose/fisiopatologia , Eletrocardiografia , Feminino , Frequência Cardíaca , Hemodinâmica , Humanos , Masculino , Consumo de Oxigênio , Estudos Prospectivos , Inquéritos e Questionários
11.
Rev. esp. cardiol. (Ed. impr.) ; 64(4): 338-341, abr. 2011. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-86339

RESUMO

Presentamos nuestra experiencia en el tratamiento quirúrgico del origen anómalo de la arteria pulmonar izquierda en 8 niños, intervenidos entre 2004 y 2009. La cardiopatía asociada más frecuentemente fue la persistencia del conducto arterioso. A 5 se realizó cirugía con circulación extracorpórea y a 3, sin ella. Se realizó división de la arteria pulmonar anómala y translocación al tronco de la arteria pulmonar. Hubo un fallecimiento de forma temprana por inestabilidad hemodinámica y una muerte más tardía por complicaciones respiratorias. La evolución de los pacientes en seguimiento ha sido satisfactoria con permeabilidad de la arteria reimplantada en todos los casos y mejoría de la clínica respiratoria; uno de ellos precisó de técnicas endoscópicas (AU)


We report our experience with the surgical treatment of anomalous origin of the left pulmonary artery in eight children between 2004 and 2009. The congenital heart disease most frequently associated with this condition was patent ductus arteriosus. Surgery was carried out with extracorporeal circulation in five children, and without, in three. The anomalous pulmonary artery was divided and translocated to the main pulmonary artery. One patient died soon after surgery because of hemodynamic instability and another died later because of respiratory complications. The other patients progressed satisfactorily during follow-up: the reimplanted artery remained patent in all cases and respiratory symptoms improved. However, one patient required endoscopic treatment (AU)


Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Artéria Pulmonar/anormalidades , Artéria Pulmonar/cirurgia , Cardiopatias Congênitas/cirurgia , Circulação Extracorpórea/métodos , Circulação Extracorpórea , Cateterismo , Ecocardiografia , Toracotomia/métodos , Cardiopatias Congênitas/diagnóstico , Estenose Traqueal/complicações , Estenose Traqueal/cirurgia , Atresia Pulmonar/complicações , Artéria Pulmonar , Stents Farmacológicos , Endoscopia
12.
Rev Esp Cardiol ; 64(4): 338-41, 2011 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-21377261

RESUMO

We report our experience with the surgical treatment of anomalous origin of the left pulmonary artery in eight children between 2004 and 2009. The congenital heart disease most frequently associated with this condition was patent ductus arteriosus. Surgery was carried out with extracorporeal circulation in five children, and without, in three. The anomalous pulmonary artery was divided and translocated to the main pulmonary artery. One patient died soon after surgery because of hemodynamic instability and another died later because of respiratory complications. The other patients progressed satisfactorily during follow-up: the reimplanted artery remained patent in all cases and respiratory symptoms improved. However, one patient required endoscopic treatment.


Assuntos
Artéria Pulmonar/cirurgia , Procedimentos Cirúrgicos Vasculares , Permeabilidade do Canal Arterial/complicações , Permeabilidade do Canal Arterial/cirurgia , Ecocardiografia , Feminino , Cardiopatias Congênitas/cirurgia , Humanos , Lactente , Recém-Nascido , Imageamento por Ressonância Magnética , Masculino , Artéria Pulmonar/anormalidades , Tomografia Computadorizada por Raios X , Resultado do Tratamento
13.
Rev Esp Cardiol ; 63(11): 1367-70, 2010 Nov.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-21070732

RESUMO

In PHACE syndrome, the acronym PHACE stands for the association of posterior fossa malformations, cervicofacial hemangiomas, arterial anomalies, coarctation and eye anomalies. We report our findings in four patients with this syndrome, in whom it was characterized by complex aortic coarctation that required not only preoperative echocardiographic investigation, but also the use of techniques such as magnetic resonance imaging and angiography. Surgical treatment was also complex. Prognosis in this condition depends primarily on cardiovascular and cerebral artery complications associated with the syndrome.


Assuntos
Coartação Aórtica/etiologia , Coartação Aórtica/complicações , Coartação Aórtica/diagnóstico , Anormalidades do Olho/complicações , Anormalidades do Olho/diagnóstico , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Síndromes Neurocutâneas/complicações , Síndromes Neurocutâneas/diagnóstico , Estudos Retrospectivos
14.
Rev. esp. cardiol. (Ed. impr.) ; 63(11): 1367-1370, nov. 2010. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-82366

RESUMO

La asociación de malformaciones de la fosa posterior, hemangiomas cervicofaciales y vasculares, coartación y alteraciones oculares es conocida con el acrónimo PHACE. Presentamos un análisis de 4 casos de este síndrome, caracterizados por coartación aórtica compleja que necesita no sólo estudio ecocardiográfico preoperatorio, sino además técnicas como resonancia magnética y angiografía. El tratamiento quirúrgico es también complejo. El pronóstico está dado por las complicaciones cardiovasculares y arteriales cerebrales propias del síndrome (AU)


In PHACE syndrome, the acronym PHACE stands for the association of posterior fossa malformations, cervicofacial hemangiomas, arterial anomalies, coarctation and eye anomalies. We report our findings in four patients with this syndrome, in whom it was characterized by complex aortic coarctation that required not only preoperative echocardiographic investigation, but also the use of techniques such as magnetic resonance imaging and angiography. Surgical treatment was also complex. Prognosis in this condition depends primarily on cardiovascular and cerebral artery complications associated with the syndrome (AU)


Assuntos
Humanos , Masculino , Feminino , Lactente , Coartação Aórtica/complicações , Coartação Aórtica/genética , Coartação Aórtica/terapia , Prognóstico , Hemangioma/complicações , Hemangioma/diagnóstico , Insuficiência Cardíaca/congênito , Insuficiência Cardíaca/complicações , Coartação Aórtica/fisiopatologia , Imageamento por Ressonância Magnética/métodos , Estudos Retrospectivos , Sinais e Sintomas , Aorta Torácica/anormalidades , Aorta/anormalidades
15.
Europace ; 12(11): 1649-51, 2010 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-20543197

RESUMO

Despite advances in implantable cardioverter-defibrillator (ICD) technology, the optimal ICD implantation technique for pediatric patients has not yet been established. One increasingly used option is totally extracardiac implantation. However, concern exists about the high defibrillation threshold (DFT) at the moment of implantation or during follow-up. We report the case of a 3-year-old boy with repetitive syncopal idiopathic ventricular tachycardia episodes treated with ICD implantation using the extracardiac technique. Changing device position from abdominal to a supradiaphragmatic, solved unsafe elevated discharge impedance and DFT during follow-up.


Assuntos
Desfibriladores Implantáveis , Síncope/terapia , Taquicardia Ventricular/terapia , Pré-Escolar , Impedância Elétrica , Frequência Cardíaca/fisiologia , Humanos , Masculino , Implantação de Prótese/métodos , Radiografia , Síncope/diagnóstico por imagem , Taquicardia Ventricular/diagnóstico por imagem , Resultado do Tratamento
16.
Circulation ; 121(22): 2427-36, 2010 Jun 08.
Artigo em Inglês | MEDLINE | ID: mdl-20497977

RESUMO

BACKGROUND: Fetal growth restriction (FGR) affects 5% to 10% of newborns and is associated with increased cardiovascular mortality in adulthood. The most commonly accepted hypothesis is that fetal metabolic programming leads secondarily to diseases associated with cardiovascular disease, such as obesity, diabetes mellitus, and hypertension. Our main objective was to evaluate the alternative hypothesis that FGR induces primary cardiac changes that persist into childhood. METHODS AND RESULTS: Within a cohort of fetuses with growth restriction identified in fetal life and followed up into childhood, we randomly selected 80 subjects with FGR and compared them with 120 normally grown fetuses, matched for gender, birth date, and gestational age at birth. Cardiovascular assessment was performed in childhood (mean age of 5 years). Compared with control subjects, children with FGR had a different cardiac shape, with increased transversal diameters and more globular cardiac ventricles. Although left ejection fraction was similar among the study groups, stroke volume was reduced significantly, which was compensated for by an increased heart rate to maintain output in severe FGR. This was associated with subclinical longitudinal systolic dysfunction (decreased myocardial peak velocities) and diastolic changes (increased E/E' ratio and E deceleration time). Children with FGR also had higher blood pressure and increased intima-media thickness. For all parameters evaluated, there was a linear increase with the severity of growth restriction. CONCLUSIONS: These findings suggest that FGR induces primary cardiac and vascular changes that could explain the increased predisposition to cardiovascular disease in adult life. If these results are confirmed, the impact of strategies with beneficial effects on cardiac remodeling should be explored in children with FGR.


Assuntos
Retardo do Crescimento Fetal/diagnóstico por imagem , Cardiopatias Congênitas/diagnóstico por imagem , Remodelação Ventricular , Adulto , Criança , Pré-Escolar , Estudos de Coortes , Ecocardiografia , Feminino , Retardo do Crescimento Fetal/fisiopatologia , Seguimentos , Coração/embriologia , Cardiopatias Congênitas/fisiopatologia , Humanos , Recém-Nascido , Masculino , Estudos Prospectivos , Remodelação Ventricular/fisiologia
17.
Rev. esp. cardiol. (Ed. impr.) ; 62(9): 1050-1054, setp. 2009. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-72702

RESUMO

Los dispositivos Amplatzer se utilizan en el tratamiento percutáneo de la comunicación interauricular ostium secundum (CIA-OS), el ductus arterioso persistente (PDA) y la comunicación interventricular muscular (CIV-m). Hay muy poca experiencia con estos dispositivos en niños menores de 1 año. Entre enero de 2001 y enero de 2008 se trató a 22 niños menores de 1 año sintomáticos; 3 tenían CIA-OS; 15, PDA y 4, CIV-m. Todos los procedimientos fueron exitosos. No observamos complicaciones inmediatas o a mediano plazo. El cierre percutáneo de estos defectos con dispositivos Amplatzer es una técnica eficaz y segura en niños menores de 1 año sintomáticos que de otro modo requerirían cirugía (AU)


Amplatzer devices are used for the percutaneous closure of ostium secundum atrial septal defects, muscular ventricular septal defects, and patent ductus arteriosus. However, very little experience has been gained in using these devices in infants under 1 year of age. Between January 2001 and January 2008, 22 symptomatic infants aged under 1 year underwent percutaneous treatment: three had an ostium secundum atrial septal defect, 15 had patent ductus arteriosus, and 4 had a muscular ventricular septal defect. All the procedures were completed successfully. No immediate or medium-term complications were observed. Closure of these types of defect using an Amplatzer device in infants under 1 year of age, who would otherwise require surgery, is a safe and effective procedure (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Canal Arterial , Canal Arterial/fisiologia , Cateterismo Cardíaco/instrumentação , Cateterismo Cardíaco/métodos , Aortografia/métodos , Canal Arterial/fisiopatologia , Canal Arterial , Estudos Retrospectivos , Aortografia/instrumentação , Aortografia/tendências , Hemodinâmica/fisiologia
18.
Rev Esp Cardiol ; 62(9): 1050-4, 2009 Sep.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-19712627

RESUMO

Amplatzer devices are used for the percutaneous closure of ostium secundum atrial septal defects, muscular ventricular septal defects and patent ductus arteriosus. However, very little experience has been gained in using these devices in infants under 1 year of age. Between January 2001 and January 2008, 22 symptomatic infants aged under 1 year underwent percutaneous treatment: three had an ostium secundum atrial septal defect, 15 had patent ductus arteriosus, and four had a muscular ventricular septal defect. All the procedures were completed successfully. No immediate or medium-term complications were observed. Closure of these types of defect using an Amplatzer device in infants under 1 year of age, who would otherwise require surgery, is a safe and effective procedure.


Assuntos
Permeabilidade do Canal Arterial/cirurgia , Comunicação Interatrial/cirurgia , Comunicação Interventricular/cirurgia , Dispositivo para Oclusão Septal , Humanos , Lactente , Estudos Retrospectivos
19.
Pediatr. catalan ; 66(1): 14-17, ene.-feb. 2006. ilus
Artigo em Ca | IBECS | ID: ibc-046547

RESUMO

Introducción. El nacimiento anómalo de la arteria pulmonarizquierda (sling de la arteria pulmonar) es una malformacióncardiaca en la que la arteria pulmonar izquierdanace de la derecha y se sitúa entre tráquea y esófago. Provocasíntomas respiratorios como consecuencia de la compresióndel bronquio principal derecho y la tráquea. Caso clínico. Lactante de 7 meses de edad con episodios de dificultad respiratoria desde los 3 meses de vida catalogados de bronquitis. Diagnosticado de sling de la arteria pulmonar, se realizó cirugía correctora con desinserción de la API y anastomosis directa al lado izquierdo del tronco de la arteria pulmonar. Comentarios. El origen anómalo de la arteria pulmonar izquierda o sling de la arteria pulmonar es un raro anillo vascular que requiere un alto índice de sospecha en lactantes con sintomatología respiratoria recurrente. El diagnóstico precoz de esta enfermedad es crucial, porque puede conducir a un severo compromiso respiratorio que puede amenazar la vida e incluso producir la muerte antes del año de edad. Una adecuada evaluación de las anomalías asociadas del árbol traqueo-bronquial es importante para decidir la cirugía y mejorar el pronóstico. Revisamos la literatura de esta rara entidad, en sus aspectos epidemiológicos, fisiopatológicos, clínicos, diagnósticos y quirúrgicos


Introduction. The anomalous left pulmonary artery(pulmonary artery sling) is a congenital condition in whichthe left pulmonary artery arises from the right pulmonaryartery forming a sling between the trachea and the esophagusand leading to respiratory symptoms by compressionof the right main stem bronchus and trachea.Case Report. A 7 month old infant presented with respiratorydistress since 3 months of age, for which he hadbeen diagnosed with bronchitis. The diagnosis of pulmonaryartery sling was made and he underwent a surgicalrepair with detachment of the aberrant left pulmonary arteryand reimplantation to the left side of the main pulmonaryartery.Comments. The anomalous origin of the left pulmonaryartery known as pulmonary artery sling is a rare formof vascular ring that requires a high index of suspicion ininfants with recurrent respiratory symptomatology. Theearly recognition of this condition is crucial because thesepatients may experience life-threatening respiratory compromiseand early death. An adequate assessment of theanomalies of the tracheobronchial tree is very importantin order to improve surgical planning and prognosis. Theauthors review the literature and discuss the epidemiology,pathophysiology, clinical presentation and diagnosis,and surgical aspects of this anomaly


Assuntos
Masculino , Lactente , Humanos , Artéria Pulmonar/anormalidades , Anastomose Cirúrgica/métodos , Artéria Pulmonar/cirurgia , Doenças Respiratórias/etiologia
20.
Rev Esp Cardiol ; 58(5): 592-5, 2005 May.
Artigo em Espanhol | MEDLINE | ID: mdl-15899202

RESUMO

We report our experience with stenting of the ductus arteriosus in three neonates. Two patients had pulmonary atresia with an intact interventricular septum and one had critical pulmonary stenosis. Radiofrequency ablation was used to open the atretic pulmonary valve in two patients. In all three patients implanting a stent avoided the need for surgical creation of a Blalock-Taussig shunt. In two patients the procedure was scheduled as elective surgery, and in one it was done as an emergency procedure. Ductus arteriosus stenting is an alternative to palliative cardiac surgery.


Assuntos
Permeabilidade do Canal Arterial/complicações , Permeabilidade do Canal Arterial/cirurgia , Atresia Pulmonar/complicações , Estenose da Valva Pulmonar/complicações , Stents , Feminino , Humanos , Recém-Nascido , Masculino
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