1.
Pol J Pharmacol Pharm
; 32(6): 889-91, 1980.
Artigo
em Inglês
| MEDLINE
| ID: mdl-7243685
RESUMO
The studies of chronic toxicity of the preparation M-71 (Craviten) were carried out on rats and mice. The body weight, absolute and relative weight or organs, haematocrit, the number of erythrocytes and leukocytes, the proportional content of leukocytes, OB value, activity of aminotransferases (AspAT and AlAT), the level of glucose in the blood serum and the histopathology of some organs were investigated. Moreover, in rats receiving M-71 intraperitoneally, the amount of electrolytes and the daily excretion of urine was studied. The results suggest that M-71 did not change the investigated parameters.
Assuntos
Antiarrítmicos/toxicidade , Etilenodiaminas/toxicidade , Administração Oral , Animais , Contagem de Células Sanguíneas , Glicemia/análise , Peso Corporal/efeitos dos fármacos , Feminino , Hematócrito , Injeções Intraperitoneais , Masculino , Camundongos , Camundongos Endogâmicos BALB C , Tamanho do Órgão/efeitos dos fármacos , Ratos , Transaminases/análise
2.
Folia Med Cracov
; 20(4): 487-92, 1978.
Artigo
em Polonês
| MEDLINE
| ID: mdl-756855