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1.
IDCases ; 34: e01912, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37886696

RESUMO

Hydatid disease is caused by the larvae of the parasite Echinococcus granulosus and, less commonly, Echinococcus multilocularis in the endemic regions. A hydatid cyst of Echinococcus granulosus commonly develops in the liver and lungs of the affected individual and rarely occurs in the brain, bones, and heart. The spinal hydatidosis comprises 50% of the cases affecting the bones, which usually leads to severe morbidities. We present a case of a 52-year-old Afghan woman presented to the hospital with Gibbus deformity, complaining of lower back pain and flaccid paraplegia for one year. Findings of Magnetic Resonance Imaging of the lumbosacral spine were suggestive of a hydatid cyst involving the vertebrae with extension to the paravertebral soft tissue, leading to acute kyphosis, severe canal stenosis, and cord compression. Treatment included complete cyst removal. The diagnosis was confirmed by gross and microscopic evaluation of the cyst contents. The patient was discharged after significant pain relief and deformity correction. Vertebral hydatidosis is notorious for its recurrence despite vigorous surgical and medical treatment. The hydatid cyst grows rapidly and can cause irreversible damage to the spinal cord in neglected cases. Currently, the best treatment approach is complete surgical removal of the cyst, irrigation with a scolicidal agent, and postoperative follow-up with a long-term course of albendazole. Spinal hydatidosis is a rare, severe disease with significant morbidity. Despite significant scientific advances in understanding of disease pathogenesis, the parasite's predilection for the spine and the influence of host-specific factors on anatomical manifestations remain a mystery.

2.
Ann Med Surg (Lond) ; 85(4): 1088-1091, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37113935

RESUMO

Fibroadenoma (FA) in ectopic male breast tissue is extremely rare. The ectopic breast tissue (EBT) is mostly appearing along the milk line; however, uncommon locations are also seen, such as the present case. Case Presentation: The authors report a 19-year-old male presenting with intestinal obstruction. The patient underwent laparoscopic surgery, and an excisional biopsy of the lesion was done. The histopathologic result confirms FA arising from EBT. This case is reported for its rarity. It indicates that FA should always be considered when there is an intra-abdominal suspicious mass. Discussion: EBT presenting as FA is also reported in the face, posterior neck, chest, middle back, buttocks, vulvar, and thighs. In this case, the authors present a EBT presented as a FA in the intra-abdomen of a young male patient, causing intestinal obstruction. FA in the male breast is rare; however, benign breast parenchyma showing FA in the intra-abdomen of a male patient is extremely rare. Conclusion: When a tumor is palpated in the milk line, the existence of FA should be taken into consideration. FA of the male EBT in the intra-abdomen is extremely rare. However, a close follow-up of the patient is strongly recommended, as the carcinoma arising from FA has a very poor prognosis.

3.
Int J Surg Case Rep ; 105: 108098, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37018950

RESUMO

INTRODUCTION: Pseudomyxoma pleurii is a rare disease that is defined by the pleural extension of pseudomyxoma peritonei, usually secondary to a mucinous neoplasm of the appendix or ovary. It is characterized by diffuse mucinous deposits on the pleural surface. CASE PRESENTATION: A 31-year-old woman presented to the hospital with dyspnea, an increased respiratory rate, and decreased oxygen saturation. Following an appendectomy for a perforated mucinous appendiceal tumor eight years ago, the patient underwent multiple surgeries for the resection of mass deposits in the peritoneal cavity. At presentation, her chest computed tomography with contrast revealed cystic mass deposits on the right-side pleura with a massive multi-locular pleural effusion mimicking hydatid cyst. Upon histopathologic examination, multiple small cystic structures lined by tall columnar epithelium with basally placed bland nuclei floating in the mucin pools were noted. CLINICAL DISCUSSION: Pseudomyxoma peritonei often leads to abdominal distention, intestinal blockage, anorexia, cachexia, and eventually death. It rarely spreads outside the abdomen, and its extension to the pleura is extremely unusual, with only a small number of cases documented in the literature to date. Radiologically, pseudomyxoma pleurii may resemble hydatid cyst of the lung and pleura. CONCLUSION: Pseudomyxoma pleurii is a rare entity with a poor prognosis that usually arises secondary to Pseudomyxoma peritonei. The risk of morbidity and mortality is reduced by early diagnosis and treatment. The present case places emphasis on the inclusion of pseudomyxoma pleurii in the differential diagnosis of pleural lesions in patients with the history of appendiceal or ovarian mucinous tumors.

4.
Int J Surg Case Rep ; 105: 107979, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36933408

RESUMO

INTRODUCTION AND IMPORTANCE: Teratoma is a germ cell tumor originating from pluripotent germ cells and embryonal cells that commonly occurs in the gonads with only 15 % of it arising in extragonadal sites. In infants and children, teratomas of the head and neck are uncommon that comprise 0.47 %-6 % of all teratomas, and their occurrence in parotid gland is extremely rare. It is considered a diagnostic pitfall preoperatively, and their definite diagnosis can only be made upon surgery followed by histopathological examination. CASE PRESENTATION: We present a unique case of parotid gland teratoma in a 9-month-old girl who was brought to the hospital by her parents with right side parotid region swelling since birth. The ultrasonographic findings were suggestive of cystic hygroma. Upon surgery, the mass was completely excised with a part of parotid gland. The diagnosis of mature teratoma was made based on the histopathologic examination. No tumor recurrence was noted during the 4-month postoperative follow-up. CLINICAL DISCUSSION: Teratoma of the parotid gland is an extremely rare entity that may mimic diverse benign and malignant tumors of the salivary gland. Patients often present to the health care facility with a parotid gland swelling leading to defacement. Complete surgical resection of the tumor is considered the best treatment approach with careful preservation of facial nerve. CONCLUSION: Due to the scarcity of information available regarding the behavior and clinical management of parotid gland teratoma in the literature, a good follow-up of patient is required to exclude potential recurrency and neurological deficit.

5.
Urol Case Rep ; 46: 102296, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36506796

RESUMO

Hydatid cyst of Echinococcus granulosus usually develops in liver and lungs of the affected individual and is considered a common health problem in endemic regions. Although, the cyst can be found in less common locations, such as brain, heart, and bones, the urinary bladder is extremely rare that may mimic malignancy radiologically and creates a diagnostic dilemma for clinicians and radiologists. Here we present a unique case of hydatid cyst in the urinary bladder with associated eosinophilic cystitis.

6.
BMC Cancer ; 21(1): 71, 2021 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-33446123

RESUMO

BACKGROUND: Breast cancer is the second most common causes of women's death, worldwide. Data on risk factors associated with female breast cancer in the Afghan population is very limited. The aim of our study was to identifying risk factor associated with female breast cancer in Afghanistan. METHODS: A retrospective case-control study was conducted with inclusion of 201 cases and 201 controls. Patient information was collected by interviewing the patient through a structured questionnaire. Histopathological information was collected from the hospital integrated laboratory management system. The data was analyzed by using logistic regression with univariate and multivariable analyses to determine the association between breast cancer and predictors. RESULTS: The results of the current study showed that factors such as: age (OR = 1.02; 95%CI: 0.99-1.04; p-0.148); age at menarche (OR = 0.83; 95%CI: 0.72-0.92; p-0.008); age at first baby (OR = 1.14; 95%CI: 1.07-1.20; p- < 0.001); illiteracy (OR = 1.93; 95%CI: 1.16-3.22; p-0.011); smoking (OR = 2.01; 95%CI: 1.01-3.99; p-0.04) and family history of cancer (OR = 1.98; 95%CI: 1.18-3.32; p-0.009) were significantly associated with breast cancer. However, our study did not demonstrate any statistically significant correlation between breast cancer and some of the predictors that were previously highlighted in literature, such as: marital status, Body Mass Index (BMI), use of hormonal contraceptive, breastfeeding and exercise. CONCLUSION: Our study demonstrated that age at menarche, and age at first baby birth, illiteracy, smoking and family history of cancer were significant risk factors associated with development of breast cancer among women in Afghanistan. Health education of women regarding aforementioned predisposing factors are therefore, expected to be valuable in decreasing the burden of breast cancer with reduction of its burden on the healthcare system in Afghanistan.


Assuntos
Índice de Massa Corporal , Neoplasias da Mama/epidemiologia , Carcinoma Ductal de Mama/epidemiologia , Carcinoma Lobular/epidemiologia , Centros de Atenção Terciária/estatística & dados numéricos , Adulto , Afeganistão/epidemiologia , Fatores Etários , Neoplasias da Mama/patologia , Carcinoma Ductal de Mama/patologia , Carcinoma Lobular/patologia , Estudos de Casos e Controles , Feminino , Seguimentos , Humanos , Menarca , Pessoa de Meia-Idade , Prognóstico , Estudos Retrospectivos , Fatores de Risco , Adulto Jovem
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