[Purine and pyrimidine metabolism in Francisella tularensis]. / Metabolizm purinov i pirimidinov u Francisella tularensis.

The assimilation and mutual transformation of exogenous purine and pyrimidine bases and their nucleosides in the known subspecies of F. tularensis have been studied by means of radio-labeled compounds. The possibility of using the specific features of the metabolism of these compounds in F. tularensis, established in this study, for taxonomy and differential diagnosis has been demonstrated.

[Culture properties of the causative agent of tularemia isolated in natural foci in Stavropol Territory, the Kalmyk ASSR and the Armenian SSR]. / Svoistva kul'tur vozbuditelia tuliaremii, vydelennykh v prirodnykh ochagakh Stavropol'skogo kraia, Kalmytskoi ASSR i Armianskoi SSR.

The strains isolated in natural foci of the Stavropol Territory and the Armenian SSR have been found to belong to the holarctic race of Francisella tularensis, biovar II. In natural foci of the Kalmyk ASSR the strains belonging to biovars I and II have been isolated. The study of the tularecinogenicity of the cultures has revealed the existence of strains which are not sensitive to their own tularecins. The phenomenon of tularecinogenicity in F. novocida has been established. Avirulent strain 319/38 belonging to the non-arctic race is recommended as an indicator strain for the determination of tularecinogenicity.

[Cytochemical changes in the peripheral blood leukocytes of guinea pigs inoculated against plague, tularemia and anthrax]. / Tsitokhimicheskie izmeneniia v leikotsitakh perifericheskoi krovi u morskikh svinok, privitykh protiv chumy, tuliaremii i sibirskoi iazvy.

The immunization of guinea pigs with trivaccine and monovaccines against plaque, tularemia and anthrax induces a decrease in the activity of acidic phosphatase in lymphocytes, as well as a decrease in the number of lymphocytes containing this enzyme. A decrease in the activity of alkaline phosphatase and peroxidase had been found to occur in neutrophil leukocytes. Besides, neutrophil leukocytes have shown an increase in the activity of acidic phosphatase and nonspecific esterases. The study based on the evaluation of the activity of the above-mentioned enzymes in lymphocytes and neutrophils has not revealed the predominant influence exercised by any of the antigens, different in their nature and used separately or in the form of a combined preparation, on immunogenesis.