Factores asociados al reingreso hospitalario en pacientes con trastorno bipolar en Valle del Cauca, Colombia / Factors related with hospital readmission in patients with bipolar disorder in Valle del Cauca, Colombia

RESUMEN Objetivo Identificar factores asociados con el reingreso hospitalario en pacientes con trastorno bipolar (TB) en un hospital psiquiátrico y desarrollar un modelo explicativo del riesgo de reingreso. Método Estudio observacional longitudinal retrospectivo a partir de base de datos secundaria aportada por el Hospital Psiquiátrico Departamental Universitario del Valle. Estadística: análisis de supervivencia utilizando un modelo de regresión Cox. Se definió como variable dependiente el riesgo de reingreso y como variables independientes algunas sociodemográficas y clínicas. Resultados Se obtuvo una asociación estadísticamente significativa entre el riesgo de reingreso y las variables: falta de red de apoyo al no tener acudiente HR=1,33 [IC 95% 1,02-1,72; (p=0,034)] y falta de adherencia al tratamiento HR=2,33 [IC 95% 1,87-2,90; (p=0,000)]. Conclusión Para disminuir el reingreso hospitalario por TB, se deben priorizar las intervenciones en los casos de pacientes que no tengan acudiente y haya inadecuada adherencia al tratamiento; esta última, a partir de la percepción por parte del médico especialista. Enfocarse sobre estos dos factores puede incidir sobre los reingresos.

ABSTRACT Objective To identify the factors associated with hospital readmission in patients with bipolar disorder between 2011 and 2017 in a psychiatric hospital in order to develop an explanatory model of the risk of rehospitalization. Method Retrospective longitudinal observational study based on a secondary database provided by the Hospital Psiquiátrico Departamental Universitario del Valle. Statistics: Survival analysis using a Cox regression model. The risk of readmission was defined as a dependent variable and some sociodemographic and clinical variables were defined as independent variables. Results From the multivariate model of Cox Regression, a statistically significant association was obtained between the risk of readmission and the variables: lack of support network due to lack of retentive HR=1.33 [95% CI 1.02-1.72; (p=0.034)] and not having adherence to the treatment HR=2.33 [95% CI 1.87-2.90; (p=0.000)]. Conclusion In order to reduce hospital readmission due to bipolar disorder, interven-tions should be prioritized in cases where patients do not have a guardian and there is inadequate adherence to the treatment; the latter perceived by the specialist doctor. Focusing on these two factors can influence readmissions.

Antibiotic susceptibility profile and prevalence of mecA and lukS-PV/lukF-PV genes in Staphylococcus aureus isolated from nasal and pharyngeal sources of medical students in Ecuador.

BACKGROUND: Staphylococcus aureus is a common nasal colonizer in 20-30% of the general population. When mucosal and cutaneous barriers are disrupted, S. aureus can cause severe infections. While MRSA nasal carriers have an increased risk of infections when compared to non-carriers, prolonged exposure to the hospital environment may cause an increase in carriage of MRSA. MATERIALS AND METHODS: A survey questionnaire was filled for analyzing risk factors of colonization. Swab isolates were identified as S. aureus by traditional microbiological assays. Antibiotic susceptibility profiles were performed following the CLSI standard guidelines. Multiplex PCR was conducted to determine the presence of genes mecA and lukS-PV/lukF-PV. Chi-squared, univariate, and multivariate logistic regressions were applied to find statistically significant associations between risk factors and the presence of S. aureus and MRSA. RESULTS: One hundred and eighty-six isolates were identified as S. aureus. The strains showed high resistance to penicillin, oxacillin, azithromycin, erythromycin, clindamycin (inducible), and tetracycline. The overall prevalence of MRSA in medical students was 45.9% [40.4-51.6] 95% CI. PCR showed a prevalence of mecA gene in MRSA isolates of 6.1% while lukS-PV/lukF-PV gene was present in 3.2% [1.2-6.9] 95% CI of the S. aureus samples. The risk factors frequency of antibiotic intake and repeated visits to hospitals demonstrated statistical significance. CONCLUSION: S. aureus and MRSA isolates have a high prevalence of colonization, and antibiotic resistance in the population studied. MRSA resistance was not related to the presence of the mecA gene. The prevalence of PVL genes was low, but it could represent a risk because they are circulating in the community.

Prevalencia de trastornos mentales en menores de edad atendidos en un hospital psiquiátrico departamental / Prevalence of mental disorders in children treated in a public psychiatric hospital

RESUMEN Objetivo Determinar la prevalencia de los trastornos mentales presentados en menores de edad en un hospital psiquiátrico departamental. Método Estudio de prevalencia de periodo. Se empleó una base de datos secundaria suministrada por el Hospital Psiquiátrico Universitario del Valle (HPUV) de Santiago de Cali, proveniente del registro de la historia clínica sistematizada correspondiente al año 2014. La población estuvo conformada por los pacientes menores de edad que consultaron durante el periodo, se utilizó la totalidad de los registros disponibles en la base de datos. Resultados Del total de consultas atendidas se encontró que el 35,7% (755) correspondía al sexo femenino y el 64,3% al masculino (1 361). El principal diagnostico psiquiátrico atendido en esta población fue el episodio depresivo con 11,6% seguido por los trastornos mixtos de la conducta y de las emociones con un 8,5%. Conclusiones La evolución en el tiempo de la salud mental no ha cambiado significativamente. La pasada encuesta nacional de salud mental 2015 presenta resultados similares al encontrado en el presente estudio, particularmente en la región pacífica, donde la depresión y trastornos de conducta son más prevalentes.(AU)

ABSTRACT Objective To determine the prevalence of mental disorders in children treated at a regional psychiatric hospital. Materials and Methods Period prevalence study. A secondary database was supplied by the Hospital Psiquiátrico Universitario del Valle (HPUV) of Santiago de Cali. This database came from the systematized clinical history of the year 2014. The population consisted of underage patients who consulted during the period. All the records available in the database were used. Results Of the total number of children who visited the clinic, 35.7% (755) were females and 64.3% were males (1 361). The main psychiatric diagnosis observed in this population was depressive episode (11.6%), followed by mixed behavioral and emotional disorder (8.5%). Conclusions The evolution of mental health over time has not changed significantly. The 2015 National Mental Health Survey presents similar results to those found in this study, particularly in the Pacific region, where depression and behavioral disorders are more prevalent.(AU)

[Prevalence of mental disorders in children treated in a public psychiatric hospital]. / Prevalencia de trastornos mentales en menores de edad atendidos en un hospital psiquiátrico departamental.

OBJECTIVE: To determine the prevalence of mental disorders in children treated at a regional psychiatric hospital. MATERIALS AND METHODS: Period prevalence study. A secondary database was supplied by the Hospital Psiquiátrico Universitario del Valle (HPUV) of Santiago de Cali. This database came from the systematized clinical history of the year 2014. The population consisted of underage patients who consulted during the period. All the records available in the database were used. RESULTS: Of the total number of children who visited the clinic, 35.7% (755) were females and 64.3% were males (1 361). The main psychiatric diagnosis observed in this population was depressive episode (11.6%), followed by mixed behavioral and emotional disorder (8.5%). CONCLUSIONS: The evolution of mental health over time has not changed significantly. The 2015 National Mental Health Survey presents similar results to those found in this study, particularly in the Pacific region, where depression and behavioral disorders are more prevalent.

OBJETIVO: Determinar la prevalencia de los trastornos mentales presentados en menores de edad en un hospital psiquiátrico departamental. MÉTODO: Estudio de prevalencia de periodo. Se empleó una base de datos secundaria suministrada por el Hospital Psiquiátrico Universitario del Valle (HPUV) de Santiago de Cali, proveniente del registro de la historia clínica sistematizada correspondiente al año 2014. La población estuvo conformada por los pacientes menores de edad que consultaron durante el periodo, se utilizó la totalidad de los registros disponibles en la base de datos. RESULTADOS: Del total de consultas atendidas se encontró que el 35,7% (755) correspondía al sexo femenino y el 64,3% al masculino (1 361). El principal diagnostico psiquiátrico atendido en esta población fue el episodio depresivo con 11,6% seguido por los trastornos mixtos de la conducta y de las emociones con un 8,5%. CONCLUSIONES: La evolución en el tiempo de la salud mental no ha cambiado significativamente. La pasada encuesta nacional de salud mental 2015 presenta resultados similares al encontrado en el presente estudio, particularmente en la región pacífica, donde la depresión y trastornos de conducta son más prevalentes.