RESUMO
The Mohr-Claussen syndrome or oro-facial-digital syndrome type II (OFD-II)] is characterised by tongue lobulation, midline cleft lip, high arched or cleft palate, broad nasal root with wide bifid nasal tip, hypertelorism, micrognathia, brachydactyly, syndactyly and polydactyly, bilateral reduplicated hallux, conductive hearing loss and normal intelligence. In view of the different modes of inheritance and the different prognoses of the two oro-facio-digital syndromes, type 1 and type 2, it is important to establish a correct diagnosis in these patients. A neonate with features of oro-facio-digital syndrome, type-II is being reported and the distinguishing clinicoradiological features with type-I are compared.
Assuntos
Fissura Palatina , Síndromes Orofaciodigitais , Humanos , HipertelorismoRESUMO
Herpes simplex encephalitis (HSE) is a leading cause of sporadic, nonepidemic viral encephalitis in children and adults. We report a very rare case of HSE with involvement of bilateral thalamus, putamen, upper pons and midbrain, with development of extrapyramidal symptoms which responded to corticosteroid therapy. A 15-mth-old female baby admitted with complaint of fever for 5 days and generalised tonic clonic seizure 10 hours before admission. On clinical examination patient was drowsy, temperature was 39.4 degrees C and vitals were stable with signs of increased intracranial tension. There were no signs of meningeal irritation. Patient gradually become unconscious in the next few hours and pupils were constricted bilaterally with development of atonia in all four limbs and neck muscles. Doll's eye phenomenon was absent.
Assuntos
Doenças dos Gânglios da Base/diagnóstico , Encefalite por Herpes Simples/diagnóstico , Encefalite por Herpes Simples/tratamento farmacológico , Antibacterianos/uso terapêutico , Antivirais/uso terapêutico , Doenças dos Gânglios da Base/tratamento farmacológico , Doenças dos Gânglios da Base/etiologia , Quimioterapia Combinada , Eletroencefalografia , Encefalite por Herpes Simples/líquido cefalorraquidiano , Encefalite por Herpes Simples/complicações , Feminino , Febre/diagnóstico , Febre/etiologia , Seguimentos , Humanos , Lactente , Imageamento por Ressonância Magnética , Manitol/uso terapêutico , Fenitoína/uso terapêutico , Medição de Risco , Convulsões/diagnóstico , Convulsões/etiologia , Índice de Gravidade de Doença , Resultado do TratamentoAssuntos
Quilotórax/microbiologia , Infecções por Escherichia coli/complicações , Imunocompetência , Amicacina/uso terapêutico , Antibacterianos/uso terapêutico , Pré-Escolar , Quilotórax/tratamento farmacológico , Infecções por Escherichia coli/tratamento farmacológico , Humanos , Masculino , Resultado do TratamentoRESUMO
Out of 6586 live born babies, 736 babies with jaundice were studied from 1st July 1996 to 30th June, 1997, in a city based medical college nursery. Physiological jaundice was present in 8.92% of all live born babies and accounted for 79.89% of babies with jaundice. Breast milk jaundice and prematurity were next common causes responsible for 5.29% each of all cases with neonatal jaundice. Septicaemia caused jaundice in 4.75% cases. Among the babies with jaundice appearing between day 4 and day 7 of life, breast milk jaundice was the commonest cause occurring in 49.25% cases. The last entity surfaced probably due to exclusive breastfeeding recently initiated in the baby friendly hospital nursery.
