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Egypt J Immunol ; 12(2): 137-42, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-17977218

RESUMO

Human T cell lymphotropic virus I and II (HTLV I/II) has been recommended to be screened for blood donors since 1988, and it become a mandatory test to get college of american Pathologists (CAP) accreditation. The present study aimed at investigating the prevalence rate of HTLV I/II among Arab blood donors, to revise whether is its screening mandatory? Thirty-thousand (30,000) Arab donors along two years attending two central hospital blood banks in Jeddah. Antibodies to HTLV I/II have been screened using enzyme immunoassay (E.I.A) and immunoblotting assay (Western blot). Results revealed zero prevalence rate. Based upon this finding, no potential risk of HTLV I/II transmission among blood donors population exist. As screening for HTLV I/II is still mandatory, it could be done on pools of sera rather than on individual serum samples, after standardization of a pooling protocol, to fulfill coast-effectiveness and reduce the coasts by 90-95%.


Assuntos
Doadores de Sangue/estatística & dados numéricos , Infecções por HTLV-I/epidemiologia , Infecções por HTLV-II/epidemiologia , Immunoblotting , Técnicas Imunoenzimáticas , Anticorpos Antivirais/sangue , Bancos de Sangue , Anticorpos Anti-HTLV-I/sangue , Infecções por HTLV-I/imunologia , Anticorpos Anti-HTLV-II/sangue , Infecções por HTLV-II/imunologia , Humanos , Masculino , Programas de Rastreamento/estatística & dados numéricos , Prevalência , Arábia Saudita/epidemiologia
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