RESUMO
A simplified Plasmodium falciparum in vivo test was carried out in Brazzaville (Congo) in April 1996. Chloroquine was prescribed at 25 mg/kg for 3 days in asymptomatic Brazzavillian school children who presented parasitemia > 800 P. falciparum trophozoïtes and lived in a highly endemic district. A massive decrease of parasitemia was observed on day 2. The percentage of resistance (presence of P. falciparum trophozoïte on day 7 in a thick blood film) was 43.5, 28 and 21 respectively (IC: 95%: 29-57, 15-41 & 10-34) at the threshold of 6, 50 and 100 parasites/microliter. In positive children on day 7 the reduction of parasitemia was > 95% and no case of R3 resistance was detected. A comparison with previous studies carried out in 1985, 1986, 1990 and 1993 in the same school using the same methodology proves the long-lasting stabilization of chloroquino-resistance for this semi-immune indigenous population.
Assuntos
Cloroquina/uso terapêutico , Resistência a Medicamentos , Malária Falciparum/tratamento farmacológico , Criança , Congo , Humanos , Imunidade Inata , Malária Falciparum/imunologiaRESUMO
Afin de repondre aux recommandations du Plan National de Developpement Sanitaire; le Programme National de Lutte contre l'Onchocercose du Congo propose une distribution de masse de l'ivermectine integree aux soins de sante primaires. Les differentes etapes necessaires a cette integration sont decrites ici
Assuntos
Ivermectina , Oncocercose/tratamento farmacológicoRESUMO
Deux strategies de distribution de masse de l'ivermectine ont ete successivement testees dans un district du Congo: equipe mobile puis postes fixes a une periode donnee. La population qui a pu etre traitee a ete la meme dans les deux cas mais une reduction de 49 pour cent des couts a pu etre obtenue avec la seconde strategie
Assuntos
Ivermectina , Oncocercose/tratamento farmacológicoRESUMO
A ce jour; aucun foyer de Schistosoma intercalatum n'a jamais ete signale au Congo; en dehors de quelques cas sporadiques depistes chez les etrangers. A ce titre le Congo restait donc le seul pays de la sous-region de l'Afrique Centrale ou ce parasite n'etait pas decrit. Mais depuis quelques mois; des cas de Schistosoma intercalatum etaient regulierement declares par le secteur operationnel No6 de la Sangha a Ouesso (Nord Congo); dans le cadre de la surveillance epidemiologique
Assuntos
Congo , Schistosoma mansoni/epidemiologia , Esquistossomose UrináriaRESUMO
A national prevalence survey of leprosy was made in june 1989 in Popular Republic of Congo: authors report results. The prevalence rate is 5.8% +/- 2.6% among people more than 15 years of age, and 10.5% of all forms are multibacillary. All patients are under DDS monotherapy. One overwhelming risk factor is leprosy antecedents in the family history; active case-finding and surveillance of contacts are recommended.
Assuntos
Hanseníase/epidemiologia , Adolescente , Adulto , Idoso , Biomarcadores/química , Congo/epidemiologia , Dapsona/uso terapêutico , Feminino , Humanos , Hanseníase/tratamento farmacológico , Hanseníase/patologia , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores de RiscoRESUMO
The authors report the results of a national prevalence survey of leprosy made in 1989 in Popular Republic of Congo. Leprosy is essentially found in rural areas and frequently causes disabilities. The prevalence rate is 5.8 +/- 2.6% among people more than 15 years of age, and 10.5% of all forms are multibacillary. All patients are under DDS monotherapy. One overwhelming risk factor is leprosy cases in the family history; active case-finding and surveillance of contact cases are recommended. Generally, leprosy is poorly understood by the general population; an educational effort is necessary.
Assuntos
Hanseníase/epidemiologia , Adolescente , Adulto , Idoso , Estudos de Casos e Controles , Congo/epidemiologia , Estudos Transversais , Cultura , Dapsona/uso terapêutico , Feminino , Educação em Saúde , Humanos , Hanseníase/psicologia , Hanseníase/terapia , Hanseníase/transmissão , Masculino , Medicina Tradicional , Pessoa de Meia-Idade , Fatores de Risco , População Rural , Fatores SocioeconômicosRESUMO
The authors give the results of a global and rapid study, using a simple methodology, of a suburban onchocerciasis focus located in the vicinity of Brazzaville. It follows, from the entomological, parasitological and clinical data, that the transmission is high inside this focus and therefore, it seems necessary to take, all measures in order to eradicate the focus.
