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1.
Pathol Biol (Paris) ; 61(6): 245-9, 2013 Dec.
Artigo em Francês | MEDLINE | ID: mdl-22627011

RESUMO

STUDY OBJECTIVE: To estimate the prevalence of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Mycoplasma genitalium (MG) in patients under 31 years of age admitted to the emergency department of the University Hospital of Montpellier, for which a urinalysis was performed. PATIENTS AND METHODS: CT, NG and MG specific real-time PCRs were performed in the urine samples from 301 patients between July 2010 and January 2011. RESULTS: CT DNA was detected in 11% of patients, NG DNA in 3.7% of patients and MG DNA in one patient. Seventy-five percent of male patients and only 13% of women were diagnosed with sexually transmitted infection (STI). No patient with leucocyturia below 10(4)/mL had a positive PCR result for one of the three bacteria. Of the patients with leucocyturia greater or equal to 10(4)/mL, CT was detected in 23.4% of men and 11% of women, NG in 19.2% of men and 1% of women, and MG in 2.1% of men. CONCLUSION: The prevalence of NG and CT detection in our population was high while that of MG was low. The diagnosis was facilitated by the use of PCR on the urine sample although this sample is not recommended for the molecular detection of bacterial agents of STIs and may explain the low detection of MG. The study allowed diagnosing STIs in 14.3% of our patient population.


Assuntos
Infecções por Chlamydia/epidemiologia , Chlamydia trachomatis , Gonorreia/epidemiologia , Infecções por Mycoplasma/epidemiologia , Mycoplasma genitalium , Neisseria gonorrhoeae , Adolescente , Adulto , Chlamydia trachomatis/isolamento & purificação , Serviço Hospitalar de Emergência/estatística & dados numéricos , Feminino , França/epidemiologia , Humanos , Masculino , Mycoplasma genitalium/isolamento & purificação , Neisseria gonorrhoeae/isolamento & purificação , Admissão do Paciente/estatística & dados numéricos , Prevalência , Adulto Jovem
2.
Antimicrob Agents Chemother ; 56(8): 4504-7, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22644030

RESUMO

We report retrospective analysis of the clinical and antimicrobial susceptibility data of 140 Streptococcus pseudopneumoniae isolates. Strains were isolated mostly from respiratory tract samples from patients with underlying diseases. In the case of infection, pneumonia, mainly aspiration pneumonia, was the most frequent (27.1% of the patients). We documented high rates of decreased susceptibilities and resistance to erythromycin and tetracycline (57% and 43% of the isolates, respectively), as well as reduced susceptibility to penicillin in 21% of the isolates.


Assuntos
Antibacterianos/farmacologia , Infecções Respiratórias/microbiologia , Infecções Estreptocócicas/microbiologia , Streptococcus/efeitos dos fármacos , Adulto , Idoso , Idoso de 80 Anos ou mais , Líquido da Lavagem Broncoalveolar/microbiologia , Criança , Eritromicina/farmacologia , Feminino , França , Humanos , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Penicilinas/farmacologia , Pneumonia Bacteriana/microbiologia , Estudos Retrospectivos , Escarro/microbiologia , Streptococcus/isolamento & purificação , Tetraciclina/farmacologia , Adulto Jovem
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