Antimicrobial Activity Developed by Scorpion Venoms and Its Peptide Component.

Microbial infections represent a problem of great importance at the public health level, with a high rate of morbidity-mortality worldwide. However, treating the different diseases generated by microorganisms requires a gradual increase in acquired resistance when applying or using them against various antibiotic therapies. Resistance is caused by various molecular mechanisms of microorganisms, thus reducing their effectiveness. Consequently, there is a need to search for new opportunities through natural sources with antimicrobial activity. One alternative is using peptides present in different scorpion venoms, specifically from the Buthidae family. Different peptides with biological activity in microorganisms have been characterized as preventing their growth or inhibiting their replication. Therefore, they represent an alternative to be used in the design and development of new-generation antimicrobial drugs in different types of microorganisms, such as bacteria, fungi, viruses, and parasites. Essential aspects for its disclosure, as shown in this review, are the studies carried out on different types of peptides in scorpion venoms with activity against pathogenic microorganisms, highlighting their high therapeutic potential.

Helicobacter Pylori: vías de transmisión / Helicobacter Pylori: Transmission Routes

La importancia de Helicobacter pylori como agente etiológico en diversas patologías se asocia con una alta tasa de morbimortalidad y genera un fuerte impacto en nuestra sociedad y en los sistemas de salud. En ese sentido, la presente revisión de literatura pretende analizar y comprender la ruta de transmisión de este patógeno con el objeto de prevenir su propagación. El conocimiento de la epidemiología y el modo de transmisión permite prevenir la propagación e identificar poblaciones de alto riesgo, especialmente en áreas que tienen altas tasas de linfoma gástrico, cáncer gástrico y úlcera gástrica.

The importance of Helicobacter pylori as an etiological agent in several pathologies is associated with a high rate of morbi mortality, which generates a strong impact in our society and in the health systems. The present literature review sought to analize and understand the route of transmission of this pathogen to prevent its spread. Knowledge of the epidemiology and mode of transmission of this pathogen is important to prevent its spread and be useful in identifying high-risk populations, especially in areas with high rates of gastric lymphoma, gastric cancer, and gastric ulcer.

Condiciones microbiológicas para el cultivo de Helicobacter pylori / Microbiological conditions for culturing Helicobacter Pylori

El diagnóstico oportuno y de cultivo de Helicobacter pylori es de gran importancia para estudiar las características de su crecimiento, así como para contribuir al conocimiento de la epidemiología clásica y molecular,la diversidad genética y la susceptibilidad frente a los antibióticos. La ubicuidad e importancia como patógenode este microorganismo a nivel mundial nos obliga a considerar y a proponer alternativas efectivas paraaislarlo e identificarlo de rutina en los laboratorios de microbiología. La presente revisión estuvo orientadaa describir la literatura referente a las condiciones requeridas para el cultivo de este microorganismo en ellaboratorio

Early diagnosis and culturing of Helicobacter pylori are of great importance for the study of the growth characteristicsof these bacteria which can contribute to knowledge of classical and molecular epidemiology, geneticdiversity and susceptibility to antibiotics. The ubiquity and importance of this pathogen throughout the worldhas forced us to consider and propose effective routine alternatives for isolating and identifying these bacteriain microbiology laboratories. This review was conducted to describe the literature concerning the conditionsfor cultivation of this organism in the laboratory