1.
Org Lett
; 3(23): 3807-10, 2001 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11700144
RESUMO
[reaction--see text] A one-step catalytic asymmetric access to alpha,beta unsaturated delta-lactones is described, using a vinylogous Mukaiyama-aldol reaction between a gamma-substituted dienolate and various aldehydes in the presence of Carreira catalyst CuF.(S)-tolBinap. This methodology has been further applied to a straightforward access to the Prelog-Djerassi lactone.