[The alterations of indices of collagen-induced aggregation of thrombocytes in qualified sportsmen in the dynamics of annual macro-cycle.]

The physical load provokes reliable alterations in the blood coagulation system, specifically increasing of blood coagulability, including increasing of thrombus formation. However, the long-term alterations in the blood coagulation system in sportsmen are still unexplored. The article demonstrates that in sportsmen parameters за aggregation capacity of thrombocytes have significant long-term alterations during annual training competition macro-cycle. The maximal alterations have to do with value of lag-phase and area under the curve of aggregation of thrombocytes. The lag-phase no the curve of aggregation of thrombocytes under stimulation with collagen is significantly increased in termination of competition period; it decreases up to control values during resting time in transition period and significantly falls down below control group indices during preparatory period. The area under the curve of aggregation of thrombocytes under stimulation with collagen is reliably decreased as to control values at the termination of competition period. It exceeds the control level during transition period and it has no reliable differences against control values during preparatory period. The alterations of functional activities of thrombocytes significantly effect functioning of immune system that modulates course of processes of adaptation to sport activities in general.