High-power Raman lasing and efficient anti-Stokes generation in mm-sized crystalline disk resonators.

We have previously experimentally observed high-power Stokes and second-order Stokes output from a mm-sized CaF2 disk using stimulated Raman scattering. A pump laser at a wavelength of 1.06 µm was coupled via a tapered fiber to the whispering gallery modes (WGM) of the disk. In this Letter, we extend this work and demonstrate the production of the first anti-Stokes sideband at power levels as high as 60 µW in near continuous-wave (CW) operation. The result is a four-component Raman comb at the output, with a wavelength range covering from 1.023 to 1.14 µm. We discuss the threshold dependence of the observed Raman lines on the crystal orientation and provide experimental validation. These advances enable the use of such mm-sized resonators as compact, efficient sources for terahertz-level frequency modulation.

Phencyclidine intoxication: insights into a growing problem of drug abuse.

Phencyclidine (PCP) is a dissociative anesthetic whose abuse is a growing problem. Historically, its effects have been considered remarkably like those of the schizophrenic state, but in vitro and in vivo neuropharmacologic data are somewhat inconsistent with the dopaminergic hypothesis of schizophrenia. The physiologic and psychiatric manifestations of PCP intoxication are diverse and somewhat dose dependent. Urine acidification may hasten drug excretion.