Smoke veil prior regularized surgical field desmoking without paired in-vivo data.

Though deep learning-based surgical smoke removal methods have shown significant improvements in effectiveness and efficiency, the lack of paired smoke and smoke-free images in real surgical scenarios limits the performance of these methods. Therefore, methods that can achieve good generalization performance without paired in-vivo data are in high demand. In this work, we propose a smoke veil prior regularized two-stage smoke removal framework based on the physical model of smoke image formation. More precisely, in the first stage, we leverage a reconstruction loss, a consistency loss and a smoke veil prior-based regularization term to perform fully supervised training on a synthetic paired image dataset. Then a self-supervised training stage is deployed on the real smoke images, where only the consistency loss and the smoke veil prior-based loss are minimized. Experiments show that the proposed method outperforms the state-of-the-art ones on synthetic dataset. The average PSNR, SSIM and RMSE values are 21.99±2.34, 0.9001±0.0252 and 0.2151±0.0643, respectively. The qualitative visual inspection on real dataset further demonstrates the effectiveness of the proposed method.

A neural network based framework for effective laparoscopic video quality assessment.

Video quality assessment is a challenging problem having a critical significance in the context of medical imaging. For instance, in laparoscopic surgery, the acquired video data suffers from different kinds of distortion that not only hinder surgery performance but also affect the execution of subsequent tasks in surgical navigation and robotic surgeries. For this reason, we propose in this paper neural network-based approaches for distortion classification as well as quality prediction. More precisely, a Residual Network (ResNet) based approach is firstly developed for simultaneous ranking and classification task. Then, this architecture is extended to make it appropriate for the quality prediction task by using an additional Fully Connected Neural Network (FCNN). To train the overall architecture (ResNet and FCNN models), transfer learning and end-to-end learning approaches are investigated. Experimental results, carried out on a new laparoscopic video quality database, have shown the efficiency of the proposed methods compared to recent conventional and deep learning based approaches.

Robust Brain Age Estimation Based on sMRI via Nonlinear Age-Adaptive Ensemble Learning.

Precise prediction on brain age is urgently needed by many biomedical areas including mental rehabilitation prognosis as well as various medicine or treatment trials. People began to realize that contrasting physical (real) age and predicted brain age can help to highlight brain issues and evaluate if patients' brains are healthy or not. Such age prediction is often challenging for single model-based prediction, while the conditions of brains vary drastically over age. In this work, we present an age-adaptive ensemble model that is based on the combination of four different machine learning algorithms, including a support vector machine (SVR), a convolutional neural network (CNN) model, and the popular GoogLeNet and ResNet deep networks. The ensemble model proposed here is nonlinearly adaptive, where age is taken as a key factor in the nonlinear combination of various single-algorithm-based independent models. In our age-adaptive ensemble method, the weights of each model are learned automatically as nonlinear functions over age instead of fixed values, while brain age estimation is based on such an age-adaptive integration of various single models. The quality of the model is quantified by the mean absolute errors (MAE) and spearman correlation between the predicted age and the actual age, with the least MAE and the highest Spearman correlation representing the highest accuracy in age prediction. By testing on the Predictive Analysis Challenge 2019 (PAC 2019) dataset, our novel ensemble model has achieved a MAE down to 3.19, which is a significantly increased accuracy in this brain age competition. If deployed in the real world, our novel ensemble model having an improved accuracy could potentially help doctors to identify the risk of brain diseases more accurately and quickly, thus helping pharmaceutical companies develop drugs or treatments precisely, and potential offer a new powerful tool for researchers in the field of brain science.

A Computer-Aided Method for Digestive System Abnormality Detection in WCE Images.

Wireless capsule endoscopy (WCE) is a powerful tool for the diagnosis of gastrointestinal diseases. The output of this tool is in video with a length of about eight hours, containing about 8000 frames. It is a difficult task for a physician to review all of the video frames. In this paper, a new abnormality detection system for WCE images is proposed. The proposed system has four main steps: (1) preprocessing, (2) region of interest (ROI) extraction, (3) feature extraction, and (4) classification. In ROI extraction, at first, distinct areas are highlighted and nondistinct areas are faded by using the joint normal distribution; then, distinct areas are extracted as an ROI segment by considering a threshold. The main idea is to extract abnormal areas in each frame. Therefore, it can be used to extract various lesions in WCE images. In the feature extraction step, three different types of features (color, texture, and shape) are employed. Finally, the features are classified using the support vector machine. The proposed system was tested on the Kvasir-Capsule dataset. The proposed system can detect multiple lesions from WCE frames with high accuracy.

Efficient Enhancement of Stereo Endoscopic Images Based on Joint Wavelet Decomposition and Binocular Combination.

The success of minimally invasive interventions and the remarkable technological and medical progress have made endoscopic image enhancement a very active research field. Due to the intrinsic endoscopic domain characteristics and the surgical exercise, stereo endoscopic images may suffer from different degradations which affect its quality. Therefore, in order to provide the surgeons with a better visual feedback and improve the outcomes of possible subsequent processing steps, namely, a 3-D organ reconstruction/registration, it would be interesting to improve the stereo endoscopic image quality. To this end, we propose, in this paper, two joint enhancement methods which operate in the wavelet transform domain. More precisely, by resorting to a joint wavelet decomposition, the wavelet subbands of the right and left views are simultaneously processed to exploit the binocular vision properties. While the first proposed technique combines only the approximation subbands of both views, the second method combines all the wavelet subbands yielding an inter-view processing fully adapted to the local features of the stereo endoscopic images. Experimental results, carried out on various stereo endoscopic datasets, have demonstrated the efficiency of the proposed enhancement methods in terms of perceived visual image quality.

Variational based smoke removal in laparoscopic images.

BACKGROUND: In laparoscopic surgery, image quality can be severely degraded by surgical smoke, which not only introduces errors for the image processing algorithms (used in image guided surgery), but also reduces the visibility of the observed organs and tissues. To overcome these drawbacks, this work aims to remove smoke in laparoscopic images using an image preprocessing method based on a variational approach. METHODS: In this paper, we present the physical smoke model where the degraded image is separated into two parts: direct attenuation and smoke veil and propose an efficient variational-based desmoking method for laparoscopic images. To estimate the smoke veil, the proposed method relies on the observation that smoke veil has low contrast and low inter-channel differences. A cost function is defined based on this prior knowledge and is solved using an augmented Lagrangian method. The obtained smoke veil is then subtracted from the original degraded image, resulting in the direct attenuation part. Finally, the smoke free image is computed using a linear intensity transformation of the direct attenuation part. RESULTS: The performance of the proposed method is evaluated quantitatively and qualitatively using three datasets: two public real smoked laparoscopic datasets and one generated synthetic dataset. No-reference and reduced-reference image quality assessment metrics are used with the two real datasets, and show that the proposed method outperforms the state-of-the-art ones. Besides, standard full-reference ones are employed with the synthetic dataset, and indicate also the good performance of the proposed method. Furthermore, the qualitative visual inspection of the results shows that our method removes smoke effectively from the laparoscopic images. CONCLUSION: All the obtained results show that the proposed approach reduces the smoke effectively while preserving the important perceptual information of the image. This allows to provide a better visualization of the operation field for surgeons and improve the image guided laparoscopic surgery procedure.

Automatic Detection and Classification of Audio Events for Road Surveillance Applications.

This work investigates the problem of detecting hazardous events on roads by designing an audio surveillance system that automatically detects perilous situations such as car crashes and tire skidding. In recent years, research has shown several visual surveillance systems that have been proposed for road monitoring to detect accidents with an aim to improve safety procedures in emergency cases. However, the visual information alone cannot detect certain events such as car crashes and tire skidding, especially under adverse and visually cluttered weather conditions such as snowfall, rain, and fog. Consequently, the incorporation of microphones and audio event detectors based on audio processing can significantly enhance the detection accuracy of such surveillance systems. This paper proposes to combine time-domain, frequency-domain, and joint time-frequency features extracted from a class of quadratic time-frequency distributions (QTFDs) to detect events on roads through audio analysis and processing. Experiments were carried out using a publicly available dataset. The experimental results conform the effectiveness of the proposed approach for detecting hazardous events on roads as demonstrated by 7% improvement of accuracy rate when compared against methods that use individual temporal and spectral features.

A novel method for planning liver resections using deformable Bézier surfaces and distance maps.

BACKGROUND AND OBJECTIVE: For more than a decade, computer-assisted surgical systems have been helping surgeons to plan liver resections. The most widespread strategies to plan liver resections are: drawing traces in individual 2D slices, and using a 3D deformable plane. In this work, we propose a novel method which requires low level of user interaction while keeping high flexibility to specify resections. METHODS: Our method is based on the use of Bézier surfaces, which can be deformed using a grid of control points, and distance maps as a base to compute and visualize resection margins (indicators of safety) in real-time. Projection of resections in 2D slices, as well as computation of resection volume statistics are also detailed. RESULTS: The method was evaluated and compared with state-of-the-art methods by a group of surgeons (n=5, 5-31 years of experience). Our results show that theproposed method presents planning times as low as state-of-the-art methods (174 s median time) with high reproducibility of results in terms of resected volume. In addition, our method not only leads to smooth virtual resections easier to perform surgically compared to other state-of-the-art methods, but also shows superior preservation of resection margins. CONCLUSIONS: Our method provides clinicians with a robust and easy-to-use method for planning liver resections with high reproducibility, smoothness of resection and preservation of resection margin. Our results indicate the ability of the method to represent any type of resection and being integrated in real clinical work-flows.

A new look to multichannel blind image deconvolution.

The aim of this paper is to propose a new look to MBID, examine some known approaches, and provide a new MC method for restoring blurred and noisy images. First, the direct image restoration problem is briefly revisited. Then a new method based on inverse filtering for perfect image restoration in the noiseless case is proposed. The noisy case is addressed by introducing a regularization term into the objective function in order to avoid noise amplification. Second, the filter identification problem is considered in the MC context. A new robust solution to estimate the degradation matrix filter is then derived and used in conjunction with a total variation approach to restore the original image. Simulation results and performance evaluations using recent image quality metrics are provided to assess the effectiveness of the proposed methods.