[Intestine microbiocenosis in mechanical jaundice caused by obturation of biliary ducts].

AIM: Study the composition of bile and feces microflora in patients with mechanical jaundice of various geneses. MATERIALS AND METHODS: 66 feces and 25 bile samples during nasobiliary decompression were studied bacteriologically. RESULTS: In all patients disorders of normal intestine microflora were detected. Patient bile in 84% of cases was infected by bacteria among which enterococci and urease positive enterobacteria predominated. In 30% of cases in patients identical species of bacteria were simultaneously detected in bile samples and in high titers (6.0 - 6.5 lg CFU/ml) in feces. CONCLUSION: In mechanical jaundice caused by biliary duct obturation in all the patients dysbiotic events of digestive tract are registered, that defines the necessity to improve bacteriological examination of patients with mechanical jaundice and reasonability of disrupted normal intestine microflora correction.

[The role of biliary decompression and correction of dysbiosis in the treatment of obstructive jaundice].

The article providing in-depth analysis of pathogenesis of obstructive jaundice shows that this disease is manifest not only as changes at the hepatic level (cholestasis, cholehemia, cholangitis, cholangio- and lymphovenous shunts, hepatic encephalopathy) but also as marked dysbiotic disturbances due to anacholia and toxic metabolites that cause bacterial translocation and endotoxemia complicating liver insufficiency. Based on the literary data and original observations, a new scheme for the treatment of obstructive jaundice is proposed including simultaneous correction of both components of hepatoenteric turnover, also, it permits to improve the outcome of the postoperative period.