[Comparative characterization of life quality in patients with pulmonary tuberculosis after surgical treatment]. / Sravnitel'naia kharakteristika kachestva zhizni bol'nykh tuberkulezom legkikh posle khirurgicheskogo lecheniia.

The parameters of life quality were comparatively analyzed in 59 patients aged 18 to 63 years, operated on for tuberculomas and cavitary masses of the lung in 1995 to 2002. Each patient underwent atypical pneumonectomy in the volume of not more than 2 segments via anterolateral access. Life quality was assessed, by using the Medical Outcomes Study Shirt Form (SF-36) developed by John E. Ware (Health Institute, New England Medical Center, Boston, Massachusetts). This study demonstrates that timely surgery in combination with chemotherapy can significantly improve all the constituents of life quality in patients with pulmonary tuberculosis. The assessment of the trend of life quality parameters helps to optimize a management policy and individualize further physical, psychoemotional, social, and working rehabilitation.

[Prognosis of the course of complicated ulcer disease and mortality in aged and senile patients]. / Prognoz techeniia oslozhnennoi iazvennoibolezni i letal'nosti u bol'nykh pozhilogo i starcheskogo vozrasta.

The developed system for forecasting the course of the disease in elderly and senile patients made it possible to distinguish two variants of the ulcer course: favorable and unfavorable. Its application confirmed that it is possible to use the forecast evaluation system in studies of remote results. In case of an unfavorable forecast, this provides the ground for urgent recommendations for surgical treatment in this group of patients without waiting for life-threatening complications to develop.

[Therapeutic and diagnostic tactics in complication of ulcer disease in elderly and aged]. / Lechebno-diagnosticheskaia taktika pri oslozhneniiakh iazvennoi bolezni v pozhilom i starcheskom vozraste.

In 78% of cases the ulcerative disease in elderly age proceeds with complications and presents a serious surgical problem. The specificity of elderly patients is the combination of several pathologies, on background of which the ulcerative disease proceeds. The level of an expressiveness of accompanying pathology influences on the prognosis of disease course and on the choice of medical tactics. Therefore for objectivization of state heaviness of the patient group mark systems of an estimation MODS and APACHE III are used. The interventions in gastroduodenal bleedings for the patients of elderly age should be differentiated and depended on a risk degree of bleeding relapse and adequate estimation of MODS heaviness. In 55.4% of the elderly patients the ulcerative perforation occur without antecedent history. Therefore indications to sewing of ulcers, including little-invasive interventions, should be extended in this group of the patients. The size of radical surgical interventions in absence of manifestation of the polyorganic insufficiency for the elderly patients should be the same, as for the younger patients.

[Pathophysiological features of duodenal ulcers in elderly and senile patients]. / Patofiziologicheskie osobennosti izvennoi bolezni dvenadtsatiperstnoi kishki u bol'nykh pozhilogo i starcheskogo vozrasta.

The following conclusions can be drawn on the basis of the research results: 1. There is no reliable distinction between central hemodynamics and gastric blood flow indices in patients from different age groups. 2. The blood flow in the stomach wall is in a distinct direct proportion to acid production. 3. The gastric blood flow is doubled in most patients with acid peptic ulcers, as compared with the norm. 4. The role of the ischemic factor in the development of duodenal ulcers is not pronounced in elderly patients.

[Pancreatoduodenal resection in cancer of the head of the pancreas]. / Pankreatoduodenal'naia rezektsiia pri rake golovki podzheludochnoi zhelezy.

The nearest results of surgical treatment of 375 patients with carcinoma of the pancreatic head and of 104 patients with cancer of other organs of the pancreatoduodenal area are described. Radical operations were made on 62 of them. Resectability was 16.5%, lethality--9.7%, postoperative complications were noted in 35.5% of the patients.

[Temporary perfusion substitution of liver and spleen functions in patients with peritonitis]. / Vremennoe perfuzionnoe zameshchenie funktsii pecheni i selezenki u bol'nykh peritonitom.

Thirty-one patients with generalized purulent peritonitis of various etiology were examined; a new perfusion method with the use of isolated live hepatocytes and xenospleen fragments was applied in the intensive therapy complex in the early period after a cavitary operation in 16 patients. It is shown that the suggested method has significant advantages over the traditional methods in that it causes effective detoxification, improves microcirculation, and reduces the indicators of the cytologic syndrome. Application of the hybrid system of detoxification in patients with peritonitis made it possible to reduce the lethality among the most serious patients with infectious-toxic shock and polyorganic insufficiency.