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1.
Phys Med Biol ; 50(5): 1011-7, 2005 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-15798273

RESUMO

This paper describes the application of the SRNA Monte Carlo package for proton transport simulations in complex geometry and different material compositions. The SRNA package was developed for 3D dose distribution calculation in proton therapy and dosimetry and it was based on the theory of multiple scattering. The decay of proton induced compound nuclei was simulated by the Russian MSDM model and our own using ICRU 63 data. The developed package consists of two codes: the SRNA-2KG, which simulates proton transport in combinatorial geometry and the SRNA-VOX, which uses the voxelized geometry using the CT data and conversion of the Hounsfield's data to tissue elemental composition. Transition probabilities for both codes are prepared by the SRNADAT code. The simulation of the proton beam characterization by multi-layer Faraday cup, spatial distribution of positron emitters obtained by the SRNA-2KG code and intercomparison of computational codes in radiation dosimetry, indicate immediate application of the Monte Carlo techniques in clinical practice. In this paper, we briefly present the physical model implemented in the SRNA package, the ISTAR proton dose planning software, as well as the results of the numerical experiments with proton beams to obtain 3D dose distribution in the eye and breast tumour.


Assuntos
Prótons , Planejamento da Radioterapia Assistida por Computador/métodos , Tomografia Computadorizada por Raios X/métodos , Algoritmos , Mama/efeitos da radiação , Neoplasias da Mama/radioterapia , Elétrons , Olho/efeitos da radiação , Neoplasias Oculares/radioterapia , Humanos , Modelos Teóricos , Método de Monte Carlo , Distribuição Normal , Imagens de Fantasmas , Intensificação de Imagem Radiográfica , Interpretação de Imagem Radiográfica Assistida por Computador , Radiometria , Radioterapia Conformacional , Espalhamento de Radiação , Software , Fatores de Tempo
2.
IEEE Trans Inf Technol Biomed ; 8(4): 428-38, 2004 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15615033

RESUMO

The problem of synthesizing the standard 12-lead electrocardiogram (ECG) from the signals recorded using three special ECG leads is studied in detail. The implementation of that concept into the design of a new mobile ECG transtelephonic system is presented. The system has two separate units: a stationary diagnostic-calibration center and a mobile ECG device with integrated electrodes. The patient records by himself three special leads with the mobile ECG recorder and sends data via cellular phone to the personal computer in the diagnostic center where standard 12-lead ECG is numerically reconstructed on the base of the patient transformation matrix previously calculated into the calibration process. The experimental study shows high accuracy of the reconstructed ECG.


Assuntos
Diagnóstico por Computador/instrumentação , Eletrocardiografia Ambulatorial/instrumentação , Armazenamento e Recuperação da Informação/métodos , Sistemas Computadorizados de Registros Médicos , Isquemia Miocárdica/diagnóstico , Telecomunicações/instrumentação , Telemedicina/instrumentação , Atividades Cotidianas , Algoritmos , Diagnóstico por Computador/métodos , Eletrocardiografia Ambulatorial/métodos , Desenho de Equipamento , Análise de Falha de Equipamento , Humanos , Miniaturização , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Telemedicina/métodos , Telemetria/instrumentação , Telemetria/métodos
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