Assuntos
Doença de Crohn/complicações , Doença de Crohn/tratamento farmacológico , Infecções por Citomegalovirus/complicações , Adulto , Anticorpos Monoclonais/uso terapêutico , Antivirais/uso terapêutico , Azatioprina/uso terapêutico , Infecções por Citomegalovirus/tratamento farmacológico , Ganciclovir/uso terapêutico , Fármacos Gastrointestinais/uso terapêutico , Humanos , Imunossupressores/uso terapêutico , Infliximab , Masculino , Fator de Necrose Tumoral alfa/antagonistas & inibidoresRESUMO
INTRODUCTION: Crohn's disease of the stomach is rare. There is nearly always concomitant disease in the small bowel or colon. Gastric involvement occurs rarely as an isolated entity. Upper endoscopy is sensitive for detecting subtle disease but more extended lesions can mimic neoplasms such us linitis. Exégèse: A 74-year old female was admitted to hospital with abdominal pain, vomiting and weight loss. Upper endoscopy and radiology aspects was suspicious of gastric linitis. Multiple endoscopic biopsies of the stomach showed one granuloma, chronic inflammation and Helicobacter Pylori. Because of the importance of obstructive syndrome, the patient underwent surgery. The resected stomach concluded to a Crohn's disease. CONCLUSION: Through this observation, we review clinical characteristics, diagnostic difficulties and treatment options of Crohn's disease of the stomach.
Assuntos
Doença de Crohn/diagnóstico , Gastrite/diagnóstico , Idoso , Doença de Crohn/cirurgia , Diagnóstico Diferencial , Feminino , Gastrite/cirurgia , Humanos , Linite Plástica/diagnóstico , Neoplasias Gástricas/diagnósticoRESUMO
Alpha heavy chain disease is a rare affection in the West and reported mainly in developing countries with the improvement of hygienic conditions, the disease become rare in Tunisia, the last case was reported in 1991. The aim of the study is to report a new Tunisian case and to describe clinical, endoscopical and histological characteristics of the disease. The patient in a 37 years old male, presented with chronic diarrhoea associated with malabsorption syndrome. The diagnosis of alpha heavy chain disease was confirmed by histological examination of the resected intestine after surgery for intestinal obstruction. The patient received chemotherapy. The follow up is of two months.