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Int J Gynecol Cancer ; 31(2): 272-278, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33468564

RESUMO

The British Gynecological Cancer Society and the British Association of Gynecological Pathologists established a multidisciplinary consensus group comprising experts in surgical gynecological oncology, medical oncology, genetics, and laboratory science, and clinical nurse specialists to identify the optimal pathways to BRCA germline and tumor testing in patients with ovarian cancer in routine clinical practice. In particular, the group explored models of consent, quality standards identified at pathology laboratories, and experience and data from pioneering cancer centers. The group liaised with representatives from ovarian cancer charities to also identify patient perspectives that would be important to implementation. Recommendations from these consensus group deliberations are presented in this manuscript.


Assuntos
Proteína BRCA1 , Proteína BRCA2 , Carcinoma Epitelial do Ovário/genética , Neoplasias Ovarianas/genética , Consenso , Feminino , Predisposição Genética para Doença , Testes Genéticos/normas , Mutação em Linhagem Germinativa , Humanos , Reino Unido
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