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1.
Radiats Biol Radioecol ; 56(4): 405-413, 2016 Jul.
Artigo em Inglês, Russo | MEDLINE | ID: mdl-30703300

RESUMO

Regularities of changes in the content of (137)Cs in green fodder during the remote period after the CNPP accident depending on application of agro-technical and agrochemical activities are analyzed. It is revealed that the use of mineral fertilizers reduces receipt of (137)Cs from the soil to forage and further to a food chain. It is also established that agrochemical activities are more effective than agro-technical ones.


Assuntos
Acidente Nuclear de Chernobyl , Contaminação Radioativa de Alimentos/prevenção & controle , Monitoramento de Radiação , Poluentes Radioativos do Solo/efeitos da radiação , Ração Animal/efeitos da radiação , Animais , Bovinos , Radioisótopos de Césio/isolamento & purificação , Radioisótopos de Césio/toxicidade , Humanos , Carne/efeitos da radiação , Leite/efeitos da radiação , República de Belarus , Federação Russa , Poluentes Radioativos do Solo/química , Ucrânia
3.
Probl Endokrinol (Mosk) ; 26(5): 70-2, 1980.
Artigo em Russo | MEDLINE | ID: mdl-7191999

RESUMO

The blood level of sugar, serum level of cholesterol and triglyceride were not changed in female rats aged between 3 to 14-16 months, whereas insulin and somatomedin levels were increased. In 24-month-old persistent estrous rats the increased insulin, cholesterol and trigliceride levels were found. The oral glucose tolerance test revealed a decrease in glucose utilization, delay of reactive insulinemia and abolishment of an increase in glucose-induced somatomedinemia.


Assuntos
Envelhecimento , Carboidratos/sangue , Lipídeos/sangue , Animais , Glicemia/análise , Colesterol/sangue , Estro , Jejum , Feminino , Anticorpos Anti-Insulina/análise , Gravidez , Ratos , Somatomedinas/sangue , Triglicerídeos/sangue
4.
Biull Eksp Biol Med ; 89(7): 88-90, 1980 Jul.
Artigo em Russo | MEDLINE | ID: mdl-6996759

RESUMO

N-nitrosomethylurea (NMU, 20 mg/kg) was administered to rats intraperitoneally on the 21st day of pregnancy. F1 progeny aged 3 months showed a decrease in glucose utilization and in somatomerin content as measured by the glucose tolerance test. The insulin serum level did not differ from control. The cholesterol blood level was higher in the offspring of NMU-treated rats. The ability of diethylstilbestrol to inhibit the compensatory ovarian hypertrophy was decreased in 3-month-old female hemicastrated rats whose mothers had been exposed to NMU. Administration of the antidiabetic drug buformin decreased 3.5-fold the malignant neurogenic tumor incidence in rats transplacentally treated with NMU.


Assuntos
Antineoplásicos , Biguanidas/uso terapêutico , Buformina/uso terapêutico , Troca Materno-Fetal , Metilnitrosoureia/antagonistas & inibidores , Neoplasias Experimentais/prevenção & controle , Compostos de Nitrosoureia/antagonistas & inibidores , Animais , Glicemia/análise , Castração , Colesterol/sangue , Feminino , Insulina/sangue , Neoplasias Experimentais/induzido quimicamente , Gravidez , Ratos , Somatomedinas/sangue , Triglicerídeos/sangue
5.
Carcinogenesis ; 1(12): 975-8, 1980.
Artigo em Inglês | MEDLINE | ID: mdl-11272113

RESUMO

N-Nitrosomethylurea (NMU) (20 mg/kg) was i.p. administered to rats on the 21st day of pregnancy. A decrease of glucose utilisation in the oral glucose tolerance test was found in 3 month old female progeny of NMU-treated rats. The serum insulin level did not differ from control, but serum cholesterol level was higher in offspring of NMU-treated rats. The ability of diethylstilboestrol to inhibit compensatory ovarian hypertrophy was decreased in female hemicastrated 3 month old rats whose mothers were treated with NMU. Postnatal administration of the antidiabetic drug buformin decreased the malignant neurogenic tumor incidence 3.5 times (to rats transplacentally treated with NMU).


Assuntos
Buformina/uso terapêutico , Dietilestilbestrol/análogos & derivados , Hipoglicemiantes/uso terapêutico , Metilnitrosoureia/toxicidade , Neoplasias Experimentais/prevenção & controle , Animais , Buformina/administração & dosagem , Buformina/farmacologia , Colesterol/sangue , Carboidratos da Dieta/farmacocinética , Dietilestilbestrol/farmacologia , Metabolismo Energético/efeitos dos fármacos , Feminino , Teste de Tolerância a Glucose , Hipertrofia , Hipoglicemiantes/administração & dosagem , Hipoglicemiantes/farmacologia , Sistema Hipotálamo-Hipofisário/fisiopatologia , Insulina/sangue , Neoplasias Renais/induzido quimicamente , Neoplasias Renais/embriologia , Neoplasias Renais/prevenção & controle , Masculino , Troca Materno-Fetal , Neoplasias Experimentais/induzido quimicamente , Neoplasias Experimentais/embriologia , Neoplasias de Tecido Nervoso/induzido quimicamente , Neoplasias de Tecido Nervoso/embriologia , Neoplasias de Tecido Nervoso/prevenção & controle , Neoplasias do Sistema Nervoso/induzido quimicamente , Neoplasias do Sistema Nervoso/embriologia , Neoplasias do Sistema Nervoso/prevenção & controle , Ovariectomia , Ovário/efeitos dos fármacos , Ovário/patologia , Gravidez , Efeitos Tardios da Exposição Pré-Natal , Ratos , Somatomedinas/deficiência
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