RESUMO
Brachytelephalangic chondrodysplasia punctata is a rare congenital skeletal dysplasia. Within the heterogeneous group of chondrodysplasia punctata, the brachytelephalangic type is noteworthy because it has a better prognosis than do the other types. We report a case of brachytelephalangic chondrodysplasia punctata diagnosed by ultrasound imaging at 30 weeks' gestation; it was associated with polyhydramnios and a normal cervical spinal canal. Imaging features are described and differential diagnosis with other forms of chondrodysplasia punctata is discussed.
Assuntos
Condrodisplasia Punctata/diagnóstico por imagem , Poli-Hidrâmnios/diagnóstico por imagem , Adulto , Condrodisplasia Punctata/genética , Feminino , Idade Gestacional , Humanos , Recém-Nascido , Masculino , Poli-Hidrâmnios/genética , Gravidez , Resultado da Gravidez , Ultrassonografia Pré-NatalRESUMO
A fraction of the dialyzed patients remains hypertensive despite achievement of the "dry weight" and will eventually require a pharmacological antihypertensive treatment. There is only scarce randomized intervention trials available in those patients so it is difficult to estimate whether the cardiovascular benefit of the treatment is related to blood pressure lowering per se or to class or drug specific properties. This paper reviews the different class of antihypertensive drugs focusing on their advantages and disadvantages in dialysis patients. On a practical ground, prescription will be driven by pharmacokinetics considerations and mostly according to specific indications pertinent to cardiovascular complications associated with hypertension.
