Brain tumor segmentation based on optimized convolutional neural network and improved chimp optimization algorithm.

Reliable and accurate brain tumor segmentation is a challenging task even with the appropriate acquisition of brain images. Tumor grading and segmentation utilizing Magnetic Resonance Imaging (MRI) are necessary steps for correct diagnosis and treatment planning. There are different MRI sequence images (T1, Flair, T1ce, T2, etc.) for identifying different parts of the tumor. Due to the diversity in the illumination of each brain imaging modality, different information and details can be obtained from each input modality. Therefore, by using various MRI modalities, the diagnosis system is capable of finding more unique details that lead to a better segmentation result, especially in fuzzy borders. In this study, to achieve an automatic and robust brain tumor segmentation framework using four MRI sequence images, an optimized Convolutional Neural Network (CNN) is proposed. All weight and bias values of the CNN model are adjusted using an Improved Chimp Optimization Algorithm (IChOA). In the first step, all four input images are normalized to find some potential areas of the existing tumor. Next, by employing the IChOA, the best features are selected using a Support Vector Machine (SVM) classifier. Finally, the best-extracted features are fed to the optimized CNN model to classify each object for brain tumor segmentation. Accordingly, the proposed IChOA is utilized for feature selection and optimizing Hyperparameters in the CNN model. The experimental outcomes conducted on the BRATS 2018 dataset demonstrate superior performance (Precision of 97.41 %, Recall of 95.78 %, and Dice Score of 97.04 %) compared to the existing frameworks.

Brain tumor segmentation of MRI images: A comprehensive review on the application of artificial intelligence tools.

BACKGROUND: Brain cancer is a destructive and life-threatening disease that imposes immense negative effects on patients' lives. Therefore, the detection of brain tumors at an early stage improves the impact of treatments and increases the patients survival rates. However, detecting brain tumors in their initial stages is a demanding task and an unmet need. METHODS: The present study presents a comprehensive review of the recent Artificial Intelligence (AI) methods of diagnosing brain tumors using MRI images. These AI techniques can be divided into Supervised, Unsupervised, and Deep Learning (DL) methods. RESULTS: Diagnosing and segmenting brain tumors usually begin with Magnetic Resonance Imaging (MRI) on the brain since MRI is a noninvasive imaging technique. Another existing challenge is that the growth of technology is faster than the rate of increase in the number of medical staff who can employ these technologies. It has resulted in an increased risk of diagnostic misinterpretation. Therefore, developing robust automated brain tumor detection techniques has been studied widely over the past years. CONCLUSION: The current review provides an analysis of the performance of modern methods in this area. Moreover, various image segmentation methods in addition to the recent efforts of researchers are summarized. Finally, the paper discusses open questions and suggests directions for future research.

Breast tumor localization and segmentation using machine learning techniques: Overview of datasets, findings, and methods.

The Global Cancer Statistics 2020 reported breast cancer (BC) as the most common diagnosis of cancer type. Therefore, early detection of such type of cancer would reduce the risk of death from it. Breast imaging techniques are one of the most frequently used techniques to detect the position of cancerous cells or suspicious lesions. Computer-aided diagnosis (CAD) is a particular generation of computer systems that assist experts in detecting medical image abnormalities. In the last decades, CAD has applied deep learning (DL) and machine learning approaches to perform complex medical tasks in the computer vision area and improve the ability to make decisions for doctors and radiologists. The most popular and widely used technique of image processing in CAD systems is segmentation which consists of extracting the region of interest (ROI) through various techniques. This research provides a detailed description of the main categories of segmentation procedures which are classified into three classes: supervised, unsupervised, and DL. The main aim of this work is to provide an overview of each of these techniques and discuss their pros and cons. This will help researchers better understand these techniques and assist them in choosing the appropriate method for a given use case.

Investigation of Effectiveness of Shuffled Frog-Leaping Optimizer in Training a Convolution Neural Network.

One of the leading algorithms and architectures in deep learning is Convolution Neural Network (CNN). It represents a unique method for image processing, object detection, and classification. CNN has shown to be an efficient approach in the machine learning and computer vision fields. CNN is composed of several filters accompanied by nonlinear functions and pooling layers. It enforces limitations on the weights and interconnections of the neural network to create a good structure for processing spatial and temporal distributed data. A CNN can restrain the numbering of free parameters of the network through its weight-sharing property. However, the training of CNNs is a challenging approach. Some optimization techniques have been recently employed to optimize CNN's weight and biases such as Ant Colony Optimization, Genetic, Harmony Search, and Simulated Annealing. This paper employs the well-known nature-inspired algorithm called Shuffled Frog-Leaping Algorithm (SFLA) for training a classical CNN structure (LeNet-5), which has not been experienced before. The training method is investigated by employing four different datasets. To verify the study, the results are compared with some of the most famous evolutionary trainers: Whale Optimization Algorithm (WO), Bacteria Swarm Foraging Optimization (BFSO), and Ant Colony Optimization (ACO). The outcomes demonstrate that the SFL technique considerably improves the performance of the original LeNet-5 although using this algorithm slightly increases the training computation time. The results also demonstrate that the suggested algorithm presents high accuracy in classification and approximation in its mechanism.

Osteolysis: A Literature Review of Basic Science and Potential Computer-Based Image Processing Detection Methods.

Osteolysis is one of the most prominent reasons of revision surgeries in total joint arthroplasty. This biological phenomenon is induced by wear particles and corrosion products that stimulate inflammatory biological response of surrounding tissues. The eventual responses of osteolysis are the activation of macrophages leading to bone resorption and prosthesis failure. Various factors are involved in the initiation of osteolysis from biological issues, design, material specifications, and model of the prosthesis to the health condition of the patient. Nevertheless, the factors leading to osteolysis are sometimes preventable. Changes in implant design and polyethylene manufacturing are striving to improve overall wear. Osteolysis is clinically asymptomatic and can be diagnosed and analyzed during follow-up sessions through various imaging modalities and methods, such as serial radiographic, CT scan, MRI, and image processing-based methods, especially with the use of artificial neural network algorithms. Deep learning algorithms with a variety of neural network structures such as CNN, U-Net, and Seg-UNet have proved to be efficient algorithms for medical image processing specifically in the field of orthopedics for the detection and segmentation of tumors. These deep learning algorithms can effectively detect and analyze osteolytic lesions well in advance during follow-up sessions in order to administer proper treatments before reaching a critical point. Osteolysis can be treated surgically or nonsurgically with medications. However, revision surgeries are the only solution for the progressive osteolysis. In this literature review, the underlying causes, mechanisms, and treatments of osteolysis are discussed with the main focus on the possible computer-based methods and algorithms that can be effectively employed for the detection of osteolysis.

An Extended Approach to Predict Retinopathy in Diabetic Patients Using the Genetic Algorithm and Fuzzy C-Means.

The present study is developed a new approach using a computer diagnostic method to diagnosing diabetic diseases with the use of fluorescein images. In doing so, this study presented the growth region algorithm for the aim of diagnosing diabetes, considering the angiography images of the patients' eyes. In addition, this study integrated two methods, including fuzzy C-means (FCM) and genetic algorithm (GA) to predict the retinopathy in diabetic patients from angiography images. The developed algorithm was applied to a total of 224 images of patients' retinopathy eyes. As clearly confirmed by the obtained results, the GA-FCM method outperformed the hand method regarding the selection of initial points. The proposed method showed 0.78 sensitivity. The comparison of the fuzzy fitness function in GA with other techniques revealed that the approach introduced in this study is more applicable to the Jaccard index since it could offer the lowest Jaccard distance and, at the same time, the highest Jaccard values. The results of the analysis demonstrated that the proposed method was efficient and effective to predict the retinopathy in diabetic patients from angiography images.

Lung Infection Segmentation for COVID-19 Pneumonia Based on a Cascade Convolutional Network from CT Images.

The COVID-19 pandemic is a global, national, and local public health concern which has caused a significant outbreak in all countries and regions for both males and females around the world. Automated detection of lung infections and their boundaries from medical images offers a great potential to augment the patient treatment healthcare strategies for tackling COVID-19 and its impacts. Detecting this disease from lung CT scan images is perhaps one of the fastest ways to diagnose patients. However, finding the presence of infected tissues and segment them from CT slices faces numerous challenges, including similar adjacent tissues, vague boundary, and erratic infections. To eliminate these obstacles, we propose a two-route convolutional neural network (CNN) by extracting global and local features for detecting and classifying COVID-19 infection from CT images. Each pixel from the image is classified into the normal and infected tissues. For improving the classification accuracy, we used two different strategies including fuzzy c-means clustering and local directional pattern (LDN) encoding methods to represent the input image differently. This allows us to find more complex pattern from the image. To overcome the overfitting problems due to small samples, an augmentation approach is utilized. The results demonstrated that the proposed framework achieved precision 96%, recall 97%, F score, average surface distance (ASD) of 2.8 ± 0.3 mm, and volume overlap error (VOE) of 5.6 ± 1.2%.

Brain tumor segmentation based on deep learning and an attention mechanism using MRI multi-modalities brain images.

Brain tumor localization and segmentation from magnetic resonance imaging (MRI) are hard and important tasks for several applications in the field of medical analysis. As each brain imaging modality gives unique and key details related to each part of the tumor, many recent approaches used four modalities T1, T1c, T2, and FLAIR. Although many of them obtained a promising segmentation result on the BRATS 2018 dataset, they suffer from a complex structure that needs more time to train and test. So, in this paper, to obtain a flexible and effective brain tumor segmentation system, first, we propose a preprocessing approach to work only on a small part of the image rather than the whole part of the image. This method leads to a decrease in computing time and overcomes the overfitting problems in a Cascade Deep Learning model. In the second step, as we are dealing with a smaller part of brain images in each slice, a simple and efficient Cascade Convolutional Neural Network (C-ConvNet/C-CNN) is proposed. This C-CNN model mines both local and global features in two different routes. Also, to improve the brain tumor segmentation accuracy compared with the state-of-the-art models, a novel Distance-Wise Attention (DWA) mechanism is introduced. The DWA mechanism considers the effect of the center location of the tumor and the brain inside the model. Comprehensive experiments are conducted on the BRATS 2018 dataset and show that the proposed model obtains competitive results: the proposed method achieves a mean whole tumor, enhancing tumor, and tumor core dice scores of 0.9203, 0.9113 and 0.8726 respectively. Other quantitative and qualitative assessments are presented and discussed.