What advice should we give our patients to preserve their fertility and avoid needing oocyte donation in the future? - A Social Fertility Preservation program.

OBJECTIVE: To describe our fertility preservation program focusing on the number of oocytes vitrified by age. METHODS: From January 2015 to December 2016, 686 oocyte vitrification cycles were performed in our units for the social fertility preservation program. In total, 288 were donors who donated their oocytes for our oocyte-banking program, and 398 were patients who underwent elective fertility preservation. RESULTS: The mean numbers of COCs retrieved and vitrified oocytes were similar among the donor cycles (women under 30 years). In those patients over 36 years of age the mean numbers of COCs retrieved and vitrified oocytes were significantly lower. We also estimated the association between age and cancelation rates. Odd ratios (OR) for total cancelation was calculated between patients of 31-35 years and 41-45 years; the OR was 5.17 (95% CI 1.89 - 14.17) and increased up to 25.67 (95% CI 5.01 - 131.42) between patients 31-35 y and those older than 45 years. No differences were found between patients of 31-35 years and 36-40 years. The OR for total cancellation increased 3.83 (95% CI 2.06 - 7.11) and 19.00 (95% CI 4.56 - 79.11) between women 36-40 years and 41-45 years, and those older than 45 years, respectively. Finally, the oocyte survival rate in patients under 36 years of age was similar to that of our donor program (94% vs. 95%). CONCLUSIONS: Based on this study, we encouraged our patients under than 36 years of age to preserve their fertility for the future.

Corticoides en el tratamiento de la hiperemesis gravídica / Corticosteroids for treatment of hyperemesis gradvidarum

Se presenta diez casos de hiperemesis gravídica tratadas con corticoides, en gestantes dentro del primer trimestre del embarazo, cuyas edades oscilaron entre los 23 y 35 años. Como antecedentes estas pacientes habían presentado crisis anteriores de esta sintomatología, siendo tratadas con antieméticos (dimenhidrinato, metoclorpramida y domperidona), antihistamínicos e hidratación; de acuerdo a las normas clásica s, con resultados variables. Nosotros hemos utilizado corticoides asociándolos al tratamiento hídrico, tanto por vía oral como endovenosa, habiendo conseguido resultados entre muy buenos a excelentes en el 90 por ciento de los casos, dentro de las 72 horas de iniciado el tratamiento.