Perforation of the sigmoid colon following ingestion of a dental plate.

The authors report on the perforation of the sigmoid colon in a 48-year-old male following the accidental ingestion of a partial dental plate. Sharp, pointed objects may perforate the bowel and surgery should be considered. A review of the literature revealed no previously reported cases.

Case report: benign chondrolipoma of the female breast.

The authors describe a benign cartilage-containing mesenchymal tumor of the female breast. The tumor arose behind the nipple, deep within the breast, and was detected by routine mammography. The authors discuss previously reported benign cartilage-containing tumors.

Phagocytosis of Candida parapsilosis by polymorphonuclear leukocytes.

The authors present a brief case report on an unusual entity. This rare phenomenon observed in a peripheral smear is worth noting. Neutrophils and rare eosinophils show intracellular fungal cells; the size, shape, and budding are consistent with Candida parapsilosis.

Pure squamous cell carcinoma of the breast.

The authors report a case of a pure squamous cell carcinoma of the breast with osteoclast-like stromal giant cells. These rare tumors should be diagnosed only after complete sampling has excluded an adenocarcinoma with squamous metaplasia or origin in the overlying skin.

Idiopathic hypereosinophilic syndrome with polymyositis.

We have reported a case of idiopathic hypereosinophilic syndrome (HES) with polymyositis, in which there was marked eosinophilic leukocytic infiltration of the myocardium and striated skeletal muscles, particularly of the diaphragm, with foci of necrosis and areas of fibrosis. We believe this to be the first detailed report of the involvement of the diaphragm in HES.

Traumatic neuroma of the cystic duct in the absence of previous surgery.

An amputation neuroma of the cystic duct was found in the markedly fibrotic gallbladder of an 88-year-old man. Since most visceral amputation neuromas follow surgery and this patient had never undergone surgery, it is postulated that the stimulus for the neural and fibrous proliferation was leakage of bile and/or cholesterol.

Multicentric basal cell carcinoma of penile skin.

A multicentric basal cell carcinoma of the penile skin is reported. The skin adjacent to the tumor showed changes similar to those observed in sun-damaged skin. Inasmuch as the patient denied sunbathing in the nude, causation is unclear, but sun may have played a role in the genesis of the tumor.

Paget's disease of the nipple simulating malignant melanoma in a black woman.

A lesion of Paget's disease arising in the skin of the nipple in a black woman is reported. The lesion simulated histologically a malignant melanoma because of the abundance of melanin within neoplastic cells in the epidermis as well as within the underlying ductal carcinoma of the breast. It was only after differential staining that the diagnosis of Paget's disease could be substantiated unequivocally.

Pre-elastofibroma and elastofibroma (the continuum of elastic-producing fibrous tumors). A light and ultrastructural study.

A fibroproliferative lesion arising anterior to the lower end of the scapula and containing polymorphic often fiberlike deposits of weakly elastinophilic fibrillary material is described. It is compared on the light and ultrastructural level to a typical elastofibroma. The fibrillary material seen in this tumor strongly resembles that which surrounds the strongly elastinophilic deposits in the typical elastofibroma and from which the elastin is thought to be derived. It is concluded that elastin-producing tumors form a continuum; at one end of which lies the tumor we have designated pre-elastofibroma and at the other, the typical elastofibroma.

Brunner's gland adenoma of the duodenal bulb.

A case of Brunner's gland adenoma arising in the duodenal bulb is reported. The symptomatology is nonspecific and the condition may erroneously be diagnosed as malignant. The surgical management of Brunner's gland adenoma should be conservative since the lesion is not premalignant.

Fibrous mesotheliomas (pseudofibroma) of the scrotal sac: a light and ultrastructural study.

Fibrous mesotheliomas of the scrotal sac are described. Similar tumors have been previously reported as fibromas and pseudofibromas and have been considered to be non-neoplastic, reactive, fibrous lesions. Ultrastructural evidence for a mesothelial origin for these tumors is presented. The value of ultrastructural study in the classification of tumors arising in or on mesothelial lined surfaces is stressed.

Primary extramedullary plasmacytoma of the omentum associated with recurrent adenocarcinoma of the colon: first case report.

Extramedullary plasmacytomas are rare tumors, with 272 cases reported in the literature in English. Less than 10 per cent of these are located in the gastrointestinal tract. This report documents the first primary plasmacytoma of the omentum in association with a recurrent colonic adenocarcinoma. Extramedullary plasmacytoma, a B cell neoplasm, characteristically arises in areas containing lymphoid tissue. In our case the tumor most likely arose in a lymph node or nodes in the omental fat, with subsequent replacement of the entire greater omentum and involvement of the colonic serosa by direct extension. Although the extent and nature of the association between myeloma and carcinoma remain obscure, a review of the literature suggests that such association may occur more frequently than has been supposed. Further investigation would appear to be warranted.

Malignant melanoma originating from intradermal nevi. A clinicopathologic entity.

Two cases of malignant melanoma arising in preexisting intradermal nevi without a junctional element are described. These cases and the two known to have been reported previously demonstrate similar clinical and morphologic findings. These include an innocuous gross appearance, a nodular growth pattern, and deep levels of invasion. It appears that the origin of the tumor in the dermis conceals malignant transformation. The consequent time lapse and the dermal position of the lesion favor deep penetration of the tumor prior to removal.