[Changes in the flora of the oral cavity after oral topical antibiotics. Importance in antimicrobial prophylaxis in surgery of the neck and head]. / Análisis de las modificaciones en la flora de la cavidad bucal tras el uso de antibióticos tópicos orales. Importancia en la profilaxis antimicrobiana en cirugía de cabeza y cuello.

A pilot study using 5 healthy adults was performed to assess the influence of topical antibiotics and antiseptics on oral flora. Samples of saliva were cultured before and after rinsing the mouth with several solutions: clindamycin, amoxyciclin + clavulanic, povidone-iodine and placebo. The results of this study suggest that, by reducing concentrations of oral flora, topical oral antibiotic prophylaxis is justified for patients having a high risk of developing a surgical infectious complications.