RESUMO
Background: The proliferating and malignant proliferating trichilemmal cysts (MPTC) are rare adnexal tumors. We report 3 cases through which we will detail the anatomo-clinical characteristics of these tumors. Cases: Two patients, 60 and 56 years old, consulted for multiple scalp nodules, one of which had changed with the appearance of a central ulceration. The removal of the remaining scalp nodules was in favor of PTCs. The third patient presented with an ulcerative lesion occupying the vertex. Skin biopsy found trichilemmal-type keratinization associated with areas of necrosis concluding with a MPTC. Discussion: The PTC is a transitional form between the trichilemmal cyst (TC) and the MPTC. The increase in the size of a TC and ulceration are sufficient signals to suspect this evolution.
RESUMO
BACKGROUND: Surface abnormalities of the nail may be due to nail diseases or chemical abuse. So, every nail plate change does not require medical treatment. The aim of our study was to support the benefit of glycolic acid (GA) in both pathological conditions and dry, discolored nails due to cosmetics. METHODS: A prospective single open label uncontrolled study is conducted in our department from January until April 2017. We divided our cases into 2 groups: G1 (consequences of cosmetics) and G2 (pathological conditions). In G1, we used 1-2 coat of GA 50% in 1-2 sitting at weekly intervals, but we needed multiple sittings (6-12 weeks) in G2 with 2-4 coats. RESULTS: We have collected 20 cases: 12 in G1 and 8 in G2. In G1, 8 patients had good response. In G2, 6 had good response. Adverse effects were tolerable. CONCLUSION: Good response in G1 was also noted in the Indian report. The improvement in the chemotherapy side effect led us to widen the sample in order to have more credible results. GA 50% peels can offer aesthetically better looking nails. However, larger studies with a longer follow-up are required to validate the results.
