Differential effects of experimental hyperlipidemia on various types of rabbit peripheral blood lymphocyte receptors.

Rabbits fed a high-cholesterol diet for 3 months showed an increase in peripheral blood lymphocytes with membrane receptors for the Fc portion of immunoglobulin G and a decrease in lymphocytes with receptors for the Fc portion of immunoglobulin M and also with receptors for the third component of the complement. Thus our results indicate changes in lymphocyte membrane receptor expression in experimental hyperlipidemia that may supposedly influence some lymphocyte functions.