RESUMO
Psoralen therapy followed by exposure to long-wave ultraviolet (UV-A) light, a combination called PUVA therapy, stimulates pigmentation of the skin. PUVA therapy is effective in the treatment of vitiligo and hypopigmented scars. Because psoralens sensitize skin to UV-A light, phototoxic reactions are frequent. Patients with such reactions can present to the plastic surgeon because they clinically mimic thermal burns. We report a patient with vitiligo who treated herself with oral and topical psoralens and then exposed herself to sunlight. She developed an intense, burnlike reaction, with erythema, edema, and bullae. "Sunburn" may be a major injury in the psoralen user.
Assuntos
Metoxaleno/efeitos adversos , Transtornos de Fotossensibilidade/induzido quimicamente , Transtornos Relacionados ao Uso de Substâncias/complicações , Adulto , Feminino , Humanos , Metoxaleno/uso terapêutico , Terapia PUVA , Luz Solar/efeitos adversos , Vitiligo/tratamento farmacológicoRESUMO
In standard skin flaps in the rat, the effect of a delay was undetectable for the first 3 weeks and the maximum benefit was not apparent until the sixth week. At all time intervals the delay phenomenon was not as pronounced in the rat as in other species. The delay phenomenon in the rat lasts at least 30 weeks. The rat does not appear to be an ideal model for the study of skin flaps.
Assuntos
Transplante de Pele , Cirurgia Plástica/métodos , Animais , Dorso , Feminino , Sobrevivência de Enxerto , Humanos , Necrose , Coelhos , Ratos , Pele/patologia , Fatores de TempoRESUMO
An experimental technique is presented for the repair of very small veins using a biodegradable collagen tubule as an internal splint. The technique is simple and the long-term results are excellent. Variable patency rates in the first two weeks are being investigated.
