El pasado, el presente y el futuro de las matronas / No disponible

No disponible

Los antecedentes a la colegiación obligatoria de las matronas en Madrid / O plano de fundo para a concessão de licenças obrigatórias de parteiras em Madrid / The background to the mandatory professional assotiation of midwives in Madrid

El presente trabajo pretende aclarar, de manera definitiva, las fechas de constitución y los fines de las diversas asociaciones corporativas que surgieron con anterioridad a la colegiación obligatoria del año 1930 y valorar la hipótesis, tan manida, de que, antes de esa fecha, no existía entre el colectivo matronal interés por la asociación profesional (AU)

Este trabalho tem como objetivo esclarecer definitivamente, as datas da Constituição e efeitos de diversas parcerias corporativas que surgiram antes do licenciamento compulsório do ano 1930 e avaliar a hipótese, tão banal que, antes dessa data, nao existía entre o colectivo de parteiras interesse pela associação profissional (AU)

This work aims to clarify definitively, the dates of constitution and the purposes of various corporate partnerships that arose prior to the mandatory professional association in 1930 and assess the so hackneyed hypothesis that, prior to that date, did not exist between the midwives collective interest by the professional association (AU)

Critical role of ribavirin for the achievement of early virological response to HCV therapy in HCV/HIV-coinfected patients.

The response to hepatitis C virus (HCV) therapy seems to be lower in HCV/HIV-coinfected patients than in HCV-monoinfected individuals. Given that most pivotal trials conducted in coinfected patients have used the combination of pegylated interferon (pegIFN) along with fixed low doses (800 mg/day) of ribavirin (RBV), it is unclear whether HIV itself and/or suboptimal RBV exposure could explain this poorer outcome. Two well-defined end points of early virological response were evaluated in Peginterferon Ribavirina España Coinfección (PRESCO), a multicentre trial in which the combination of pegIFN plus RBV (1000 mg if body weight <75 kg and 1200 mg if >75 kg) was prescribed to coinfected patients. For comparisons, we used unpublished data from early kinetics in two other large trials, one performed in HIV-negative patients [Pegasys International Study Group (PISG)] in which RBV 1000-1200 mg/day was used and another [AIDS Pegasys Ribavirin Coinfection Trial (APRICOT)] in which HIV-positive patients received fixed low RBV doses (800 mg/day). A total of 348 HCV/HIV-coinfected patients from the PRESCO trial were analysed as well as all patients treated with pegIFN plus RBV, who completed 12 weeks of therapy in the comparative studies (435 in PISG and 268 in APRICOT). Negative serum HCV-RNA at week 4 (which has the highest positive predictive value of sustained virological response, SVR) was attained in 33.3%, 31.2% and 13% of treated patients with HCV genotype 1, respectively, in PRESCO, PISG and APRICOT. For HCV genotypes 2/3, responses were 83.7%, 84.2% and 37%, respectively. A decline lower than 2 log(10) at week 12 (which has the highest negative predictive value of SVR) was seen in 25.5%, 19.5% and 37% of HCV genotype-1-infected patients, and in 2.1%, 2.9% and 12% of genotypes-2/3-infected patients, respectively. Prescription of high RBV doses enhances the early virological response to HCV therapy in HCV/HIV-coinfected patients, with results approaching those seen in HCV-monoinfected patients.

[Does goiter constitute basically a surgical process?]. / Constituye el bocio un proceso fundamentalmente quirúrgico?

Goiter is usually a clinical manifestation present almost in all the thyroid processes. The over-simple idea of a thyroid tumoration demanding surgical resection is, unfortunately, deeply implanted in many medical and, above all, surgical environments. We tried to estimate the incidence of goiter in a series of thyroid processes and how many of them required surgery. We reviewed the surgical indications in several thyroid entities. In a series of 377 thyroidopathies, goiter was present in 345 (91.5%), 50 of which underwent surgery (12.26% of the total and 14.49 of goiters). Some of the patients were operated in other hospitals without adjusting to the aforementioned criteria and, in theory, just 36 of then should had undergone surgery (9.54% of the total and 10.43% of goiters). In conclusion, surgery has a very secondary role in the treatment of goiter.

Peritonitis meconial. / Meconium peritonitis

Hijo de madre multipara con antecedentes obstetricos de fetos macrosomicos y un obito fetal, con amenorrea incierta, polihidramnios y un parto normal. Recien nacido de 37 semanas de edad gestacional por examen fisico, con peso al nacer de 2.850 grs. Apgar 6/9, que presenta al examen gran distension abdominal, petequias, equimosis y matidez, asociada a ictericia verdinica progresiva, con ausencia de expulsion de meconio que presento una evolucion rapidamente progresiva a la peoria y muerte a las 16 hs. de vida. Radiologia que muestra calcificaciones abdominales generalizadas, comprobandose en la necropsia peritonitis meconial a gran cavidad quistica secundaria a una estenosis ileal con perforacion proximal a la misma