RESUMO
In this review of 35 patients who received repeat chymopapain injections, 41% had an excellent result, 37% had some improvement, and 22% showed no improvement. Of the 21 patients followed who had the same disc injected twice, 43% had an excellent result and 24% had no improvement. Of the three patients followed who had a different disc injected on the second occasion, one had an excellent result, and none showed no improvement. There was no significant difference between the two groups. Six patients (17%) had an anaphylactic reaction to the second injection. Five had a major reaction. Repeat chymopapain injection may be a valid treatment for a protruded disc but should not be performed until a definitive test for sensitivity is developed.
Assuntos
Anafilaxia/induzido quimicamente , Quimopapaína/administração & dosagem , Hipersensibilidade a Drogas/etiologia , Quimiólise do Disco Intervertebral/métodos , Quimopapaína/efeitos adversos , Edema/induzido quimicamente , Feminino , Humanos , Hipotensão/induzido quimicamente , Quimiólise do Disco Intervertebral/efeitos adversos , MasculinoRESUMO
The feasibility of using computer-based EEG spectral analysis to monitor the level of anaesthesia during nitrous oxide-alphaprodine anaesthesia has been established by this study. At present, this system is capable of estimating the level of anaesthesia correctly from 55 per cent to 80 per cent of the time. There are several possible clinical applications of such a monitoring system during anaesthesia. It provides a continuous estimation of the depth of anaesthesia, without requiring any special EEG training on the part of the anaesthetist. This system can also be of particular benefit during anaesthesia for critically ill patients, or in specific cases, as in neurosurgery and caesarian section when there may be periods of time when the gross clinical evaluation of depth of anaesthesia may not be precise or reliable and yet it is imperative not to deepen the anaesthesia unnecessarily. In such instances it appears that a monitoring system such as we have developed could provide valuable indication of the depth of anaesthesia. Other potential applications might be in the training of students in the clinical assessment of patients during anaesthesia and in the study of new anaesthetic agents.
