RESUMO
A prospective epidemiological study of the incidence of simple febrile convulsions (FC) was performed in a northern Swedish county. The yearly incidence was 700/100 000. The children with FC were re-examined three years later. The pre- and perinatal complications were significantly more common in the group of children with FC than in a randomly collected group of controls. The value of an extensive investigation program is discussed. Between six months and five years of age the children with FC can be separated from those with other cerebral diseases causing epileptic seizures by recording a thorough history followed by a somatic and neurological physical examination and a determination of acute blood glucose. In children less than six months of age and in children in which meningitis or encephalitis cannot be ruled out, a lumbar puncture and a blood culture should be performed. If the onset of the convulsion has been after five years of age, if the seizures are partial or have a duration of more than 30 minutes, or if signs of cerebral disease are found, the examination should be supplemented with EEG and relevant investigations. There is no need for an extensive routine program of investigations in the care of children with FC.
Assuntos
Convulsões Febris/epidemiologia , Convulsões/epidemiologia , Adolescente , Criança , Pré-Escolar , Humanos , Lactente , Meningite/complicações , Meningite/diagnóstico , Estudos Prospectivos , Convulsões Febris/complicações , Convulsões Febris/diagnóstico , SuéciaRESUMO
There are many difficulties in creating a simple and useful dosage schedule for co-trimazine treatment in children. However, it has been possible to propose a schedule based on age. No advantage can be seen in choosing doses according to weight or other measures of body size. The schedule referred to as schedule B leads to levels of both sulphadiazine and trimethoprim that are as near the optimal as possible with respect to efficacy and side-effects.
Assuntos
Infecções Bacterianas/tratamento farmacológico , Sulfadiazina/administração & dosagem , Trimetoprima/administração & dosagem , Adulto , Fatores Etários , Criança , Pré-Escolar , Esquema de Medicação , Combinação de Medicamentos , Feminino , Humanos , Lactente , Cinética , Masculino , Sulfadiazina/farmacologia , Sulfadiazina/uso terapêutico , Trimetoprima/farmacologia , Trimetoprima/uso terapêuticoRESUMO
A study of co-trimazine tablets in 52 cases of urinary tract infection in children has shown that co-trimazine is at least as effective as co-trimoxazole, in which both the sulphonamide and the trimethoprim dose is higher than with co-trimazine. The frequency of side-effects (gastro-intestinal intolerance and allergic manifestations) was low. A sucrose-free suspension of cotrimazine for use in younger children was tested and found to have very good properties, as judged by a high acceptability rate among the young patients. Only one of 44 children refused to take the medicine during the prescribed fourteen days of therapy.
Assuntos
Sulfadiazina/uso terapêutico , Trimetoprima/uso terapêutico , Infecções Urinárias/tratamento farmacológico , Adolescente , Fatores Etários , Criança , Pré-Escolar , Ensaios Clínicos como Assunto , Combinação de Medicamentos , Feminino , Humanos , Lactente , Masculino , Aceitação pelo Paciente de Cuidados de Saúde , Recidiva , Sulfadiazina/efeitos adversos , Trimetoprima/efeitos adversos , Infecções Urinárias/microbiologiaAssuntos
Epilepsia/epidemiologia , Adolescente , Fatores Etários , Criança , Pré-Escolar , Anormalidades Congênitas/complicações , Epilepsias Parciais/epidemiologia , Epilepsia/tratamento farmacológico , Epilepsia/etiologia , Epilepsia/genética , Epilepsia Tipo Ausência/epidemiologia , Feminino , Seguimentos , Humanos , Lactente , Masculino , Complicações do Trabalho de Parto , Gravidez , Complicações na Gravidez , Prognóstico , Transtornos Psicomotores/complicações , Convulsões/epidemiologia , Convulsões/genética , SuéciaRESUMO
The incidence rates of epileptic seizures and epileptic seizures with centrotemporal (Rolandic) discharges were found to be 134/100,000 and 21/100,000, respectively. These were determined in an epidemiological study in a population consisting of 52,252 children aged 0-15 years in a county in the northern part of Sweden. Epileptic seizures with Rolandic discharges represented about 16% of all the epileptic seizures (febrile convulsions not included). They were four times more common than classic petit mal with 3/sec spike-and-wave activity.
