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1.
Proc Soc Exp Biol Med ; 152(1): 116-21, 1976 May.
Artigo em Inglês | MEDLINE | ID: mdl-57624

RESUMO

The non-oncogenic rat C-type virus WF-1, isolated from a Wistar-Furth rat embryo cell line, was characterized biochemically. The purified virus has a buoyant density of 1.15 to 1.16 g/cm3 in sucrose, RNA-dependent DNA polymerase (reverse transcriptase) activity, and RNA with a sedimentation coefficient of 62 to 68 S. The viral RNA is single-stranded, and, upon treatment with heat, yields components with sedimentation coefficients of 36 S, 18 to 20 S, and 4 to 12 S.


Assuntos
Ratos/microbiologia , Retroviridae/análise , Animais , Centrifugação com Gradiente de Concentração , Dimetil Sulfóxido/farmacologia , Temperatura Alta , Peso Molecular , RNA Viral/análise , DNA Polimerase Dirigida por RNA/metabolismo , Retroviridae/enzimologia
8.
Science ; 158(3799): 377-8, 1967 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-6061888

RESUMO

Inoculation of newborn Fischer, W/Fu, or Lewis rats with the 9H virus recently isolated from leukemic rat tissues resulted in the development of peliosis hepatis. The virus was recoverable from the peliotic livers. The cystic lesions were of the parenchymal peliosis type and appeared to be the result of focal hepatic necrosis followed by hemorrhage.


Assuntos
Vírus de DNA , Hepatite A/patologia , Vírus de Hepatite , Fígado/patologia , Retroviridae , Animais , Animais Recém-Nascidos , Hemaglutinação , Hemorragia , Hepatite A/etiologia , Leucemia Experimental , Necrose , Ratos , Retroviridae/isolamento & purificação
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