RESUMO
Metastatic tumors in the breast are quite rare and constitute 0,5 to 6% of all breast malignancies. They often occur in a polymetastatic context. Gastrointestinal lesions rarely metastasize to the breast. The first case of a metastasis deposit to the breast and ovary from gastric signet-ring cell carcinoma was reported in the literature in 1999. Since this report, only 5 cases have been reported. We present a case report of a 37-year-old woman who complained of a lump in the left breast. Two months earlier, the woman underwent a subtotal gastrectomy and a total hysterectomy with double anexectomy, which histologically was diagnosed of gastric signet-ring carcinoma, disseminated with Krukenberg's tumor. In those days, the patient was following a chemotherapy treatment. A core needle biopsy of the lesion in left breast revealed cells with signet-ring features, with probably gastric origin.
RESUMO
La mejora en el manejo hematológico, la introducción de la terapia quelante y el avance en las técnicas de reproducción ha hecho que el embarazo en pacientes con betatalasemia mayor sea una realidad y que suponga un reto para los profesionales de la salud, por su enfoque multidisciplinar. Presentamos el caso de una paciente diagnosticada de betatalasemia mayor, con gestación espontánea y buen resultado tanto perinatal como materno, realizando un examen crítico y exhaustivo de la conducta seguida hasta el parto y el puerperio inmediato
Due to improvements in haematological care, the introduction of chelation therapy and the advances in reproductive techniques, pregnancy among patients with Beta-thalassaemia major is not only a reality but also a challenge for health professionals on account of its multidisciplinary approach. We report the case of a patient with Beta-thalassaemia major, with spontaneous pregnancy and a correct maternal and perinatal result, by presenting a comprehensive and critical examination of the procedures followed throughout pregnancy, delivery and the immediate puerperium
