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1.
Int J Pediatr Otorhinolaryngol ; 87: 148-53, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27368464

RESUMO

UNLABELLED: Balance disorders are common in adult patients but less usual in the pediatric population. When this symptomatology appears in children it is a cause for concern, both for parents and health-care professionals. OBJECTIVES: To explain the balance disorders in children describing a case series and to discuss the main etiologies found according to age. STUDY DESIGN: A retrospective, observational, descriptive, and cross-sectional study was conducted. POPULATION: Patients aged 1-18 years who consulted because of balance disorders at the otolaryngology department of a pediatric tertiary-care hospital between March 2012 and July 2015. RESULTS: Two hundred and six patients were included in the study. Median age was 10 years. The most common diagnoses were vestibular migraine in 21.8% of the children, ataxia in 9.22%, benign paroxysmal vertigo of childhood in 7.77%, and post-traumatic vertigo in 6.31%.Overall, 61 videonystagmographies- of which 46 were normal - and 55 video head impulse tests - which were normal in 45 and showed abnormalities in the vestibulo-ocular reflex gain in 10 - were performed. CONCLUSIONS: In a child with balance disorders, the medical history and neurotological examination are essential. Vestibular migraine is the most commonly found disorder in every age group, and most of the patients have a family history of migraine. Ancillary studies, especially the video head-impulse test, provide important data to confirm the diagnosis.


Assuntos
Ataxia/fisiopatologia , Vertigem Posicional Paroxística Benigna/fisiopatologia , Neoplasias do Sistema Nervoso Central/fisiopatologia , Labirintite/fisiopatologia , Transtornos de Enxaqueca/fisiopatologia , Otite Média com Derrame/fisiopatologia , Equilíbrio Postural , Transtornos de Sensação/fisiopatologia , Adolescente , Ataxia/complicações , Vertigem Posicional Paroxística Benigna/complicações , Neoplasias do Sistema Nervoso Central/complicações , Criança , Pré-Escolar , Estudos Transversais , Feminino , Teste do Impulso da Cabeça , Humanos , Lactente , Labirintite/complicações , Masculino , Transtornos de Enxaqueca/complicações , Otite Média com Derrame/complicações , Reflexo Vestíbulo-Ocular , Estudos Retrospectivos , Transtornos de Sensação/etiologia , Vertigem/complicações , Vertigem/fisiopatologia , Doenças Vestibulares , Testes de Função Vestibular
2.
Rev. argent. microbiol ; 45(4): 262-6, dic. 2013.
Artigo em Espanhol | LILACS, BINACIS | ID: biblio-1171795

RESUMO

Macrolide-resistant Streptococcus pneumoniae emerged in Argentina in 1995, representing 26


of invasive infection isolates in children under 5 years old. The objectives of this study were to describe the prevalence of ermB and mefA genes in macrolide-resistant S. pneumoniae isolates from acute otitis media (AOM) and to determine their genetic relatedness. Between May 2009 and August 2010, 126 S. pneumoniae isolates from 324 otherwise healthy children with a first episode of AOM were included. Twenty six of these isolates (20.6


) were resistant to erythromycin. Most frequent serotypes were: 14 (46.2


) and 9V (7.7


) carried the mefA gene, 5 (19.2


) have the ermB gene, and 1 (3.9


) both ermB + mefA. Ten clonal types were identified, mostly related to Sweden(15A)-25/ST782 (SLV63), CloneB(6A)/ST473 and England(14)-9/ ST9. This is the first study assessing the mechanisms of macrolide resistance in pneumococci isolates from pediatric AOM in Argentina and their genetic relatedness.


Assuntos
Macrolídeos/farmacologia , Otite Média/microbiologia , Streptococcus pneumoniae/efeitos dos fármacos , Antibacterianos , Argentina , Criança , Farmacorresistência Bacteriana , Humanos , Lactente , Pré-Escolar , Streptococcus pneumoniae/genética , Streptococcus pneumoniae/isolamento & purificação , Testes de Sensibilidade Microbiana
3.
Rev Argent Microbiol ; 45(1): 27-33, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23560785

RESUMO

A 16-month prospective, descriptive study was conducted on pneumococcal serotype distribution isolated from children with acute otitis media (AOM) and invasive infections (INV). Eighty-nine children with pneumococcal INV and 324 with a first episode of AOM were included. Bacterial pathogens (N = 326) were isolated from the middle-ear fluid of 250 patients. A total of 30 pneumococcal serotypes were identified. Prevalent serotypes were 14, 19A, 9V, 3, 19F, 6A, 23F, and 18C in AOM and 14, 1, 19A, 5, 12F, 6B, and 18C in INV. Potential coverage with PCV10 vaccine would be 46.5 % and 60.7 % for pneumococci involved in AOM and INV, respectively; it would be 71.7 % and 73 % with PCV13. PCV10, conjugated with a Haemophilus protein, would have an immunologic coverage of 39.9 % for AOM vs. 18.5 % with PCV13. However, differences in the prevention of INV were crucial for the decision to include the 13-valent vaccine in the national calendar for children less than two years old in Argentina.


Assuntos
Bacteriemia/microbiologia , Otite Média/microbiologia , Infecções Pneumocócicas/microbiologia , Vacinas Pneumocócicas , Streptococcus pneumoniae/classificação , Doença Aguda , Argentina/epidemiologia , Bacteriemia/epidemiologia , Criança , Pré-Escolar , Coinfecção , Feminino , Infecções por Haemophilus/epidemiologia , Haemophilus influenzae , Humanos , Lactente , Recém-Nascido , Masculino , Meningite Pneumocócica/epidemiologia , Meningite Pneumocócica/microbiologia , Otite Média/epidemiologia , Infecções Pneumocócicas/epidemiologia , Estudos Prospectivos , Sorotipagem , Streptococcus pneumoniae/isolamento & purificação , Vacinação/estatística & dados numéricos , Vacinas Conjugadas
4.
Int J Pediatr Otorhinolaryngol ; 77(6): 976-80, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23601926

RESUMO

UNLABELLED: The true incidence of acute otitis media (AOM) in neonates and infants younger than three months is unknown. In this population organisms causing AOM may disseminate leading to bacteremia, sepsis, and meningitis [1]. OBJECTIVES: To describe the clinical presentation, associated severe infections, bacteriologic etiology, and antibiotic resistance patterns of organisms isolated from the middle ear of infants younger than three months that were not vaccinated against Streptococcus pneumoniae. METHODS: Otomicroscopy was performed in all children to confirm the suspected diagnosis of AOM. When purulent effusion retained in the middle ear was diagnosed, tympanocentesis and culture of middle-ear fluid was performed by conventional methods. Serotyping was done using the Quellung technique. RESULTS: From May 2, 2009 to February 28, 2010, 52 infants met the inclusion criteria. Thirty-six were male (69.2%) and 16 were female (30.8%). From these 52 patients, 76 samples were obtained for culture. Bilateral acute suppurative otitis media was diagnosed in 24 (46.2%) infants. Of all infants, 18 (34.6%) had been treated with antibiotics before tympanocentesis. Eight patients (44.4%) had negative middle-ear fluid cultures. Sixty bacterial pathogens were isolated from the middle-ear fluid of 43 patients. Mixed infections were recorded in 14/52 patients (26.9%). Nine cultures were negative (17.3%), of which eight were from patients that had previously been treated with antibiotics. S. pneumoniae was isolated from middle-ear aspirates of 26/52 (50%) patients with acute suppurative otitis media. Twenty-two out of the 26 isolates were susceptible (84.7%) and four were intermediately susceptible to penicillin (15.3%). Streptococcus pyogenes was isolated in 3/52 (5.8%) and Haemophilus influenzae in 18/52 patients (34.6%). Five (27.8%) of these were beta-lactamase producers. Blood cultures, cerebrospinal fluid, and urine cultures were negative. Parenteral antimicrobial treatment was indicated in 29/52 (56%). CONCLUSIONS: S. pneumoniae is the most frequent pathogen to cause AOM in this age group. Empirical treatment with amoxicillin or ceftriaxone should be considered depending on clinical suspicion of severe invasive infection.


Assuntos
Otite Média/diagnóstico , Otite Média/epidemiologia , Infecções Pneumocócicas/diagnóstico , Streptococcus pneumoniae/isolamento & purificação , Doença Aguda , Fatores Etários , Argentina/epidemiologia , Estudos de Coortes , Feminino , Seguimentos , Humanos , Incidência , Lactente , Recém-Nascido , Masculino , Otite Média/microbiologia , Otite Média com Derrame/diagnóstico , Otite Média com Derrame/epidemiologia , Otite Média com Derrame/microbiologia , Otoscopia/métodos , Infecções Pneumocócicas/prevenção & controle , Vacinas Pneumocócicas/administração & dosagem , Medição de Risco , Índice de Gravidade de Doença , Streptococcus pneumoniae/imunologia , Vacinação
5.
Rev. argent. microbiol ; 45(1): 27-33, mar. 2013. tab
Artigo em Inglês | LILACS | ID: lil-672050

RESUMO

A 16-month prospective, descriptive study was conducted on pneumococcal serotype distribution isolated from children with acute otitis media (AÜM) and invasive infections (INV). Eighty-nine children with pneumococcal INV and 324 with a first episode of AOM were included. Bacterial pathogens (N = 326) were isolated from the middle-ear fluid of 250 patients. A total of 30 pneumococcal serotypes were identified. Prevalent serotypes were 14, 19A, 9V, 3, 19F, 6A, 23F, and 18C in AOM and 14, 1, 19A, 5, 12F, 6B, and 18C in INV. Potential coverage with PCV10 vaccine would be 46.5 % and 60.7 % for pneumococci involved in AOM and INV, respectively; it would be 71.7 % and 73 % with PCV13. PCV10, conjugated with a Haemophilus protein, would have an immunologic coverage of 39.9 % for AOM vs. 18.5 % with PCV13. However, differences in the prevention of INV were crucial for the decision to include the 13-valent vaccine in the national calendar for children less than two years old in Argentina.


Se realizó un estudio prospectivo descriptivo sobre la distribución de serotipos de neumococos aislados de niños con otitis media aguda (OMA) y con infecciones invasivas (INV) en un período de 16 meses. Se incluyeron 89 niños con INV neumocócicas y 324 con un primer episodio de OMA. Trescientos cuarenta y seis patógenos se aislaron de las secreciones de oído medio obtenidas de 250 pacientes. Se identificaron 30 serotipos y los más prevalentes fueron el 14, 19A, 9V, 3, 19F, 6A, 23F y 18C en OMA y el 14, 1, 19A, 5, 12F, 6B y 18C en INV. La cobertura potencial con la vacuna PCV10 sería de 46,5 % y 60,7 % para neumococos involucrados en OMA y en INV, respectivamente; con la PCV13, esta sería de 71,7 % y 73 %. La PCV10 conjugada con una proteína de Haemophilus tendría una cobertura inmunológica del 39,9 % para OMA, contra una cobertura del 18,5 % de la PCV13. Sin embargo, las diferencias en la prevención de INV fueron determinantes a la hora de considerar incorporarla al calendario nacional de vacunación para niños menores de 2 años en la Argentina.


Assuntos
Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Bacteriemia/microbiologia , Otite Média/microbiologia , Vacinas Pneumocócicas , Infecções Pneumocócicas/microbiologia , Streptococcus pneumoniae/classificação , Doença Aguda , Argentina/epidemiologia , Bacteriemia/epidemiologia , Coinfecção , Haemophilus influenzae , Infecções por Haemophilus/epidemiologia , Meningite Pneumocócica/epidemiologia , Meningite Pneumocócica/microbiologia , Otite Média/epidemiologia , Estudos Prospectivos , Infecções Pneumocócicas/epidemiologia , Sorotipagem , Streptococcus pneumoniae/isolamento & purificação , Vacinas Conjugadas , Vacinação
6.
Rev. argent. microbiol ; 45(1): 27-33, Mar. 2013. tab
Artigo em Inglês | BINACIS | ID: bin-131104

RESUMO

A 16-month prospective, descriptive study was conducted on pneumococcal serotype distribution isolated from children with acute otitis media (AÜM) and invasive infections (INV). Eighty-nine children with pneumococcal INV and 324 with a first episode of AOM were included. Bacterial pathogens (N = 326) were isolated from the middle-ear fluid of 250 patients. A total of 30 pneumococcal serotypes were identified. Prevalent serotypes were 14, 19A, 9V, 3, 19F, 6A, 23F, and 18C in AOM and 14, 1, 19A, 5, 12F, 6B, and 18C in INV. Potential coverage with PCV10 vaccine would be 46.5 % and 60.7 % for pneumococci involved in AOM and INV, respectively; it would be 71.7 % and 73 % with PCV13. PCV10, conjugated with a Haemophilus protein, would have an immunologic coverage of 39.9 % for AOM vs. 18.5 % with PCV13. However, differences in the prevention of INV were crucial for the decision to include the 13-valent vaccine in the national calendar for children less than two years old in Argentina.(AU)


Se realizó un estudio prospectivo descriptivo sobre la distribución de serotipos de neumococos aislados de niños con otitis media aguda (OMA) y con infecciones invasivas (INV) en un período de 16 meses. Se incluyeron 89 niños con INV neumocócicas y 324 con un primer episodio de OMA. Trescientos cuarenta y seis patógenos se aislaron de las secreciones de oído medio obtenidas de 250 pacientes. Se identificaron 30 serotipos y los más prevalentes fueron el 14, 19A, 9V, 3, 19F, 6A, 23F y 18C en OMA y el 14, 1, 19A, 5, 12F, 6B y 18C en INV. La cobertura potencial con la vacuna PCV10 sería de 46,5 % y 60,7 % para neumococos involucrados en OMA y en INV, respectivamente; con la PCV13, esta sería de 71,7 % y 73 %. La PCV10 conjugada con una proteína de Haemophilus tendría una cobertura inmunológica del 39,9 % para OMA, contra una cobertura del 18,5 % de la PCV13. Sin embargo, las diferencias en la prevención de INV fueron determinantes a la hora de considerar incorporarla al calendario nacional de vacunación para niños menores de 2 años en la Argentina.(AU)


Assuntos
Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Bacteriemia/microbiologia , Otite Média/microbiologia , Infecções Pneumocócicas/microbiologia , Vacinas Pneumocócicas , Streptococcus pneumoniae/classificação , Doença Aguda , Argentina/epidemiologia , Bacteriemia/epidemiologia , Coinfecção , Infecções por Haemophilus/epidemiologia , Haemophilus influenzae , Meningite Pneumocócica/epidemiologia , Meningite Pneumocócica/microbiologia , Otite Média/epidemiologia , Infecções Pneumocócicas/epidemiologia , Estudos Prospectivos , Sorotipagem , Streptococcus pneumoniae/isolamento & purificação , Vacinação/estatística & dados numéricos , Vacinas Conjugadas
7.
Acta otorrinolaringol. esp ; 64(1): 12-16, ene.-feb. 2013. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-109477

RESUMO

Introducción y objetivo: La otitis media aguda (OMA) es una de las afecciones más frecuentes en la infancia y es la causa más común de prescripción de antibióticos en pediatría. El método indicado para identificar el germen responsable en OMA es la obtención de material del oído medio para cultivo mediante timpanocentesis. El objetivo de este estudio es describir la prevalencia de gérmenes causantes de OMA en pacientes eutróficos de 1 a 120 meses, que consultaron en un hospital público pediátrico. Método: Se incluyeron pacientes eutróficos con OMA con retención de contenido purulento en oído medio y OMA supurada con drenaje insuficiente de exudado que consultaron al Servicio de Otorrinolaringología de un hospital pediátrico desde mayo del 2009 hasta agosto del 2010. Resultados: Se incluyeron en el estudio 324 pacientes de los cuales 180 (55,6%) eran varones. Mediana de edad: 8 meses (rango intercuartílico: 4-15 meses). OMA bilateral se registró en 109/324 (33,6%) pacientes (se obtuvieron 433 muestras para cultivo).Al momento del diagnóstico 37% (120/324) de los niños recibían antibioticoterapia. De estos, el 59% (71/120) presentaron desarrollo bacteriano en los cultivos. La antibioticoterapia era adecuada en el 71,8% de los casos; en el 28,2% restante no se cubría el espectro del germen aislado. Conclusión: Los microorganismos más frecuentemente aislados fueron Streptococcus pneumoniae (39,5%), Haemophilus influenzae (37,4%), Moraxella catarrhalis (6,1%) y Streptococcus pyogenes (3,0%) (AU)


Background and objective: Acute otitis media (AOM) is one of the most common diseases in childhood and is the most common cause of antibiotic prescriptions in children. The gold standard for identifying the pathogens causing AOM is tympanocentesis. This is only possible in the stage of AOM when exudate is retained in the middle ear. The aim of this study was to describe the prevalence of organisms causing AOM in eutrophic patients at a public paediatric hospital. Material and methods: We included all patients with AOM diagnosed by otomicroscopy with purulent exudate retained in middle ear and suppurative AOM with inadequate drainage consulting at the Otorhinolaryngology Department in a paediatric tertiary care centre from 2 May 2009 to 31 August 2010. Results: There were 324 patients included in the study, with 180/324 (55.6%) being male. The median age was 8 months (interquartile range: 4 to 15 months). Bilateral AOM was recorded in 109/324 (33.6%) patients (433 samples for culture were obtained by tympanocentesis in 324 patients). At diagnosis, 37% (120/324) of the children had been receiving antimicrobial treatment. Of the patients who had received antibiotics, 71/120 (59.1%) had bacterial growth in middle ear fluid (MEF) cultures, with 51/71 (71.8%) being susceptible to the antibiotic they received; 20/71 (28.2%) patients were receiving an antibiotic that did not cover the spectrum of organisms isolated. Conclusion: The pathogens most frequently isolated are Streptococcus pneumoniae (39.5%), Haemophilus influenzae (37.4%), Moraxella catarrhalis (6.1%) and Streptococcus pyogenes (3.0%) (AU)


Assuntos
Humanos , Masculino , Feminino , Lactente , Orelha Média/microbiologia , Otite Média/microbiologia , Antibacterianos/uso terapêutico , Técnicas Bacteriológicas/métodos , Doença Aguda , Hospitais Públicos , Estudos Prospectivos , Estudos Transversais
8.
Acta Otorrinolaringol Esp ; 64(1): 12-6, 2013.
Artigo em Espanhol | MEDLINE | ID: mdl-22858160

RESUMO

BACKGROUND AND OBJECTIVE: Acute otitis media (AOM) is one of the most common diseases in childhood and is the most common cause of antibiotic prescriptions in children. The gold standard for identifying the pathogens causing AOM is tympanocentesis. This is only possible in the stage of AOM when exudate is retained in the middle ear. The aim of this study was to describe the prevalence of organisms causing AOM in eutrophic patients at a public paediatric hospital. MATERIAL AND METHODS: We included all patients with AOM diagnosed by otomicroscopy with purulent exudate retained in middle ear and suppurative AOM with inadequate drainage consulting at the Otorhinolaryngology Department in a paediatric tertiary care centre from 2 May 2009 to 31 August 2010. RESULTS: There were 324 patients included in the study, with 180/324 (55.6%) being male. The median age was 8 months (interquartile range: 4 to 15 months). Bilateral AOM was recorded in 109/324 (33.6%) patients (433 samples for culture were obtained by tympanocentesis in 324 patients). At diagnosis, 37% (120/324) of the children had been receiving antimicrobial treatment. Of the patients who had received antibiotics, 71/120 (59.1%) had bacterial growth in middle ear fluid (MEF) cultures, with 51/71 (71.8%) being susceptible to the antibiotic they received; 20/71 (28.2%) patients were receiving an antibiotic that did not cover the spectrum of organisms isolated. CONCLUSION: The pathogens most frequently isolated are Streptococcus pneumoniae (39.5%), Haemophilus influenzae (37.4%), Moraxella catarrhalis (6.1%) and Streptococcus pyogenes (3.0%).


Assuntos
Orelha Média/microbiologia , Otite Média/microbiologia , Doença Aguda , Estudos Transversais , Feminino , Hospitais Públicos , Humanos , Lactente , Masculino , Estudos Prospectivos
9.
Rev Argent Microbiol ; 45(4): 262-6, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24401781

RESUMO

Macrolide-resistant Streptococcus pneumoniae emerged in Argentina in 1995, representing 26% of invasive infection isolates in children under 5 years old. The objectives of this study were to describe the prevalence of ermB and mefA genes in macrolide-resistant S. pneumoniae isolates from acute otitis media (AOM) and to determine their genetic relatedness. Between May 2009 and August 2010, 126 S. pneumoniae isolates from 324 otherwise healthy children with a first episode of AOM were included. Twenty six of these isolates (20.6%) were resistant to erythromycin. Most frequent serotypes were: 14 (46.2%), 6A (23.1%), 19F (7.7%) and 9V (7.7%). Twenty (76.9%) carried the mefA gene, 5 (19.2%) have the ermB gene, and 1 (3.9%) both ermB + mefA. Ten clonal types were identified, mostly related to Sweden(15A)-25/ST782 (SLV63), CloneB(6A)/ST473 and England(14)-9/ ST9. This is the first study assessing the mechanisms of macrolide resistance in pneumococci isolates from pediatric AOM in Argentina and their genetic relatedness.


Assuntos
Macrolídeos/farmacologia , Otite Média/microbiologia , Streptococcus pneumoniae/efeitos dos fármacos , Antibacterianos , Argentina , Criança , Pré-Escolar , Farmacorresistência Bacteriana , Humanos , Lactente , Testes de Sensibilidade Microbiana , Streptococcus pneumoniae/genética , Streptococcus pneumoniae/isolamento & purificação
10.
Rev. Argent. Microbiol. ; 45(4): 262-6, 2013 Oct-Dec.
Artigo em Espanhol | BINACIS | ID: bin-132751

RESUMO

Macrolide-resistant Streptococcus pneumoniae emerged in Argentina in 1995, representing 26


of invasive infection isolates in children under 5 years old. The objectives of this study were to describe the prevalence of ermB and mefA genes in macrolide-resistant S. pneumoniae isolates from acute otitis media (AOM) and to determine their genetic relatedness. Between May 2009 and August 2010, 126 S. pneumoniae isolates from 324 otherwise healthy children with a first episode of AOM were included. Twenty six of these isolates (20.6


) were resistant to erythromycin. Most frequent serotypes were: 14 (46.2


), 6A (23.1


), 19F (7.7


) and 9V (7.7


). Twenty (76.9


) carried the mefA gene, 5 (19.2


) have the ermB gene, and 1 (3.9


) both ermB + mefA. Ten clonal types were identified, mostly related to Sweden(15A)-25/ST782 (SLV63), CloneB(6A)/ST473 and England(14)-9/ ST9. This is the first study assessing the mechanisms of macrolide resistance in pneumococci isolates from pediatric AOM in Argentina and their genetic relatedness.


Assuntos
Macrolídeos/farmacologia , Otite Média/microbiologia , Streptococcus pneumoniae/efeitos dos fármacos , Antibacterianos , Argentina , Criança , Pré-Escolar , Farmacorresistência Bacteriana , Humanos , Lactente , Testes de Sensibilidade Microbiana , Streptococcus pneumoniae/genética , Streptococcus pneumoniae/isolamento & purificação
11.
Rev. Argent. Microbiol. ; 45(1): 27-33, 2013 Jan-Mar.
Artigo em Espanhol | BINACIS | ID: bin-133182

RESUMO

A 16-month prospective, descriptive study was conducted on pneumococcal serotype distribution isolated from children with acute otitis media (AOM) and invasive infections (INV). Eighty-nine children with pneumococcal INV and 324 with a first episode of AOM were included. Bacterial pathogens (N = 326) were isolated from the middle-ear fluid of 250 patients. A total of 30 pneumococcal serotypes were identified. Prevalent serotypes were 14, 19A, 9V, 3, 19F, 6A, 23F, and 18C in AOM and 14, 1, 19A, 5, 12F, 6B, and 18C in INV. Potential coverage with PCV10 vaccine would be 46.5


and 60.7


for pneumococci involved in AOM and INV, respectively; it would be 71.7


and 73


with PCV13. PCV10, conjugated with a Haemophilus protein, would have an immunologic coverage of 39.9


for AOM vs. 18.5


with PCV13. However, differences in the prevention of INV were crucial for the decision to include the 13-valent vaccine in the national calendar for children less than two years old in Argentina.


Assuntos
Bacteriemia/microbiologia , Otite Média/microbiologia , Infecções Pneumocócicas/microbiologia , Vacinas Pneumocócicas , Streptococcus pneumoniae/classificação , Doença Aguda , Argentina/epidemiologia , Bacteriemia/epidemiologia , Criança , Pré-Escolar , Coinfecção , Feminino , Infecções por Haemophilus/epidemiologia , Haemophilus influenzae , Humanos , Lactente , Recém-Nascido , Masculino , Meningite Pneumocócica/epidemiologia , Meningite Pneumocócica/microbiologia , Otite Média/epidemiologia , Infecções Pneumocócicas/epidemiologia , Estudos Prospectivos , Sorotipagem , Streptococcus pneumoniae/isolamento & purificação , Vacinação/estatística & dados numéricos , Vacinas Conjugadas
12.
Acta otorrinolaringol. esp ; 63(1): 21-25, ene.-feb. 2012.
Artigo em Espanhol | IBECS | ID: ibc-96268

RESUMO

Introducción: Para describir las características clínicas de los niños con complicaciones intratemporales de otitis media aguda (OMA), se realizó un trabajo retrospectivo y descriptivo durante dos años. Métodos: Se consideró mastoiditis al eritema y edema retroauricular, protrusión del pabellón auricular y caída de la pared posterior del conducto auditivo externo; laberintitis, al vértigo con o sin náuseas, vómitos y nistagmus, y parálisis facial periférica, a la ausencia o disminución de la movilidad en hemicara. Previa otomicroscopía para diagnóstico de enfermedad otológica aguda coexistente, se tomó material para estudio bacteriológico de oído medio, de absceso subperióstico o de cavidad mastoidea. Resultados: Edad media: 54,23 meses; 30% menores de 12 meses; 12/17 masculinos y 5/17 femeninos; 8/17 recibían antibioticoterapia; 7/17 presentaban fiebre; 9/17 (52,9%) con mastoiditis aguda; 7/17 (41,2%) con laberintitis y 1/17 (5,9%) con parálisis facial periférica. El 17,6% presentó complicaciones endocraneales. Todos requirieron antibioticoterapia parenteral. Se realizó miringotomía en 16/17 (94,1%); drenaje de absceso subperióstico en 3/17 (17,6%) y antromastoidectomía en 2/17 (11,8%). La bacteriología fue positiva en 9/17, aislándose Streptococcus pyogenes (S. pyogenes) en el 44% de los casos. Secuelas: una hipoacusia neurosensorial. Entre enero de 2008 y diciembre de 2009 fueron asistidos 17 pacientes con complicaciones intratemporales de OMA. Conclusión: La mastoiditis aguda es la complicación intratemporal más frecuente. S. pyogenes es prevalente en estas infecciones invasivas en nuestro medio. La resolución de la OMA complicada requiere procedimientos quirúrgicos en todos los casos (miringotomía, drenaje de absceso subperióstico o antromastoidectomía) y tratamiento antimicrobiano parenteral(AU)


Background: To describe the clinical features of intratemporal complications of acute otitis media (AOM) in children, a retrospective study was carried out for two years. Methods: We considered acute mastoiditis, presence of postauricular swelling, erythema and tenderness and anteroinferior displacement of the auricle; labyrinthitis, presence of vestibular symptoms (spontaneous nystagmus and ataxia with or without vomiting; and facial nerve palsy, absence or decreased motility in hemiface. All children underwent otomicroscopy for evidence of coexistent or recent AOM. Cultures were obtained by tympanocentesis and myringotomy, drainage of subperiosteal abscess or from granulation tissue during tympanomastoidectomy. Results: From January 2008 to December 2009, 17 patients fulfilled the entry criteria. Median age: 54.2 months. Of the 17 cases, 30% were infants younger than twelve months and most were boys (70.6%).8/17 were receiving antimicrobial treatment. Diagnoses included 9/17 (52.9%) acute mastoiditis, 7/17 (41.2%) labyrinthitis and 1/17 (5.9%) facial nerve palsy. Intracranial complications were present in 17.6%. All required intravenous antimicrobial treatment. Myringotomy was performed in 16/17, drainage of subperiosteal abscess in 3/17 and tympanomastoidectomy in 2/17. Bacteriology was positive in 9/17 cases, isolating Streptococcus pyogenes (S. pyogenes) in 44% of patients. Secuelaes: One unilateral sensorineural hearing loss. Conclusions: Acute mastoiditis is the most common complication. Labyrinthitis was diagnosed in 41.2% of cases. S. pyogenes was prevalent in these serious invasive infections in our area. Associated intracranial complications were present in 17.6% cases. Resolution of AOM complications required surgical procedures in all cases (myringotomy, drainage of subperiosteal abscess or tympanomastoidectomy) (AU)


Assuntos
Humanos , Masculino , Feminino , Lactente , Otite Média/complicações , Lobo Temporal/fisiopatologia , Otite Média/epidemiologia , Mastoidite/epidemiologia , Estudos Retrospectivos , Labirintite/epidemiologia , Paralisia Facial/epidemiologia , Microscopia
13.
Acta Otorrinolaringol Esp ; 63(1): 21-5, 2012.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-21982482

RESUMO

BACKGROUND: To describe the clinical features of intratemporal complications of acute otitis media (AOM) in children, a retrospective study was carried out for two years. METHODS: We considered acute mastoiditis, presence of postauricular swelling, erythema and tenderness and anteroinferior displacement of the auricle; labyrinthitis, presence of vestibular symptoms (spontaneous nystagmus and ataxia with or without vomiting; and facial nerve palsy, absence or decreased motility in hemiface. All children underwent otomicroscopy for evidence of coexistent or recent AOM. Cultures were obtained by tympanocentesis and myringotomy, drainage of subperiosteal abscess or from granulation tissue during tympanomastoidectomy. RESULTS: From January 2008 to December 2009, 17 patients fulfilled the entry criteria. Median age: 54.2 months. Of the 17 cases, 30% were infants younger than twelve months and most were boys (70.6%). 8/17 were receiving antimicrobial treatment. Diagnoses included 9/17 (52.9%) acute mastoiditis, 7/17 (41.2%) labyrinthitis and 1/17 (5.9%) facial nerve palsy. Intracranial complications were present in 17.6%. All required intravenous antimicrobial treatment. Myringotomy was performed in 16/17, drainage of subperiosteal abscess in 3/17 and tympanomastoidectomy in 2/17. Bacteriology was positive in 9/17 cases, isolating Streptococcus pyogenes (S. pyogenes) in 44% of patients. Secuelaes: One unilateral sensorineural hearing loss. CONCLUSIONS: Acute mastoiditis is the most common complication. Labyrinthitis was diagnosed in 41.2% of cases. S. pyogenes was prevalent in these serious invasive infections in our area. Associated intracranial complications were present in 17.6% cases. Resolution of AOM complications required surgical procedures in all cases (myringotomy, drainage of subperiosteal abscess or tympanomastoidectomy).


Assuntos
Paralisia Facial/etiologia , Labirintite/etiologia , Mastoidite/etiologia , Otite Média/complicações , Doença Aguda , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Estudos Retrospectivos , Fatores de Tempo
14.
Arch. argent. pediatr ; 102(3): 174-179, jun. 2004. tab, graf
Artigo em Espanhol | LILACS | ID: lil-472139

RESUMO

La otitis media crónica supurada es una enfermedad del oído medio caracterizada por inflamación crónica de la mucosa del oído medio y mastoides, perforación de la membrana timpánica y otorrea. Para determinar las características clínicas de la OMC en niños se realizó un estudio prospectivo, longitudinal y descriptivo durante 3 meses en el Servicio de Otorrinolaringología del Hospital Nacional de Pediatría “Prof. Dr. J. P. Garrahan”. Población, material y métodos. De los pacientes asistidos en el Servicio de ORL se seleccionaron los que cumplían con los criterios diagnósticos de otitis media crónica: otorrea (permanente o intermitente) de más de tres meses de evolución, a través de perforación timpánica documentada por otomicroscopia. Se excluyeron aquellos con sospecha de colesteatoma, enfermedades tumorales, inmunodeficiencias primarias y secundarias, anomalías craneofaciales, síndromes genéticos y los que no concurrieron a controles posteriores. A todos se les realizó otomicroscopia, toma de material para cultivo y tratamiento local inicial con alcohol 70 boricado a saturación. Resultados. De 115 niños con otitis media crónica se incluyeron 96 en el estudio (51 por ciento [n igual 49] masc menos 49 por ciento [n igual 47] fem). Edad media: 77 más o menos 43,78 meses. El tiempo medio de otorrea fue de 12 meses (rango 1 menos 175 m). Presentaban sinusopatía maxilar 48 (50 por ciento) pacientes. La otitis crónica era bilateral en 33,3 por ciento (32) y unilateral en 66,7 por ciento (64). Microbiología: se aislaron 153 gérmenes del material aspirado de oído medio, 50 por ciento (48) de los cultivos fueron polimicrobianos. Las bacterias más comunes fueron Pseudomonas aeruginosa (53/153) y Proteus (33/153). Desarrollaron gérmenes anaerobios 18/153 cultivos. El tratamiento inicial con alcohol 70 boricado a saturación resolvió la otorrea en el 77 por ciento de los casos


Assuntos
Criança , Otite Média Supurativa/complicações , Otite Média Supurativa/diagnóstico , Otite Média Supurativa/microbiologia , Otite Média Supurativa/terapia , Perfuração da Membrana Timpânica , Epidemiologia Descritiva , Estudos Longitudinais , Estudos Prospectivos
15.
Arch. argent. pediatr ; 102(3): 174-179, jun. 2004. tab, graf
Artigo em Espanhol | BINACIS | ID: bin-122714

RESUMO

La otitis media crónica supurada es una enfermedad del oído medio caracterizada por inflamación crónica de la mucosa del oído medio y mastoides, perforación de la membrana timpánica y otorrea. Para determinar las características clínicas de la OMC en niños se realizó un estudio prospectivo, longitudinal y descriptivo durante 3 meses en el Servicio de Otorrinolaringología del Hospital Nacional de Pediatría ¶Prof. Dr. J. P. Garrahan÷. Población, material y métodos. De los pacientes asistidos en el Servicio de ORL se seleccionaron los que cumplían con los criterios diagnósticos de otitis media crónica: otorrea (permanente o intermitente) de más de tres meses de evolución, a través de perforación timpánica documentada por otomicroscopia. Se excluyeron aquellos con sospecha de colesteatoma, enfermedades tumorales, inmunodeficiencias primarias y secundarias, anomalías craneofaciales, síndromes genéticos y los que no concurrieron a controles posteriores. A todos se les realizó otomicroscopia, toma de material para cultivo y tratamiento local inicial con alcohol 70 boricado a saturación. Resultados. De 115 niños con otitis media crónica se incluyeron 96 en el estudio (51 por ciento [n igual 49] masc menos 49 por ciento [n igual 47] fem). Edad media: 77 más o menos 43,78 meses. El tiempo medio de otorrea fue de 12 meses (rango 1 menos 175 m). Presentaban sinusopatía maxilar 48 (50 por ciento) pacientes. La otitis crónica era bilateral en 33,3 por ciento (32) y unilateral en 66,7 por ciento (64). Microbiología: se aislaron 153 gérmenes del material aspirado de oído medio, 50 por ciento (48) de los cultivos fueron polimicrobianos. Las bacterias más comunes fueron Pseudomonas aeruginosa (53/153) y Proteus (33/153). Desarrollaron gérmenes anaerobios 18/153 cultivos. El tratamiento inicial con alcohol 70 boricado a saturación resolvió la otorrea en el 77 por ciento de los casos(AU)


Assuntos
Criança , Otite Média Supurativa/diagnóstico , Otite Média Supurativa/terapia , Perfuração da Membrana Timpânica , Otite Média Supurativa/complicações , Otite Média Supurativa/microbiologia , Estudos Prospectivos , Estudos Longitudinais , Epidemiologia Descritiva
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