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1.
Rev Med Chil ; 136(8): 1021-6, 2008 Aug.
Artigo em Espanhol | MEDLINE | ID: mdl-18949186

RESUMO

BACKGROUND: Viral load in pediatric patients with HIV infections can help to make therapeutic decisions to modify the evolution of the disease. AIM: To evaluate viral load in positive HIV children with antiretroviral treatment. MATERIAL AND METHODS: Viral load was measured every six months during three years in fifty pediatric patients chosen randomly in aged 1 to 12 years, using the Test Monitor HIV-1 AMPLICOR, version 1.5. RESULTS: During the three years follow up, there was an increase in CD4 and CD8 lymphocyte count and decrease in the viral load. However, there was no significant relationship between lymphocyte subpopulation counts and viral loads. CONCLUSIONS: Viral load demonstrated to be an appropriate method to quantify plasma HIV-RNA. This tool can help to define the condition of a particular patient to predict clinical course of the disease and to assess the response to the treatment.


Assuntos
Fármacos Anti-HIV/uso terapêutico , Infecções por HIV/virologia , HIV-1 , Carga Viral , Distribuição por Idade , Análise de Variância , Terapia Antirretroviral de Alta Atividade , Linfócitos T CD4-Positivos/química , Linfócitos T CD8-Positivos/química , Criança , Pré-Escolar , Feminino , Seguimentos , Infecções por HIV/tratamento farmacológico , Infecções por HIV/imunologia , Humanos , Lactente , Contagem de Linfócitos , Masculino , Estatísticas não Paramétricas , Venezuela
2.
Rev. méd. Chile ; 136(8): 1021-1026, ago. 2008. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-495801

RESUMO

Background: Viral load in pediatric patients with HIV infections can help to make therapeutic decisions to modify the evolution of the disease. Aim: To evaluate viral load in positive HIV children with antiretroviral treatment. Material and methods: Viral load was measured every six months during three years in fifty pediatric patients chosen randomly in aged 1 to 12 years, using the Test Monitor HIV-1 AMPLICOR, versión 1.5. Results: During the three years follow up, there was an increase in CD4 and CD8 lymphocyte count and decrease in the viral load. However, there was no significant relationship between lymphocyte subpopulation counts and viral loads. Conclusions: Viral load demonstrated to be an appropriate method to quantify plasma HIV-RNA. This tool can help to define the condition of a particular patient to predict clinical course of the disease and to assess the response to the treatment.


Assuntos
Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , HIV-1 , Fármacos Anti-HIV/uso terapêutico , Infecções por HIV/virologia , Carga Viral , Distribuição por Idade , Análise de Variância , Terapia Antirretroviral de Alta Atividade , /química , /química , Seguimentos , Infecções por HIV/tratamento farmacológico , Infecções por HIV/imunologia , Contagem de Linfócitos , Estatísticas não Paramétricas , Venezuela
3.
Acta odontol. venez ; 44(1): 114-121, ene. 2006. ilus
Artigo em Espanhol | LILACS | ID: lil-629970

RESUMO

The purpose of this revision is to describe the actual knowledge about Human Papiloma Virus (HVP) and its relation with the oral cavity and periodontium, supported by a bibliographic revision. A descriptive and documental investigation was conducted mainly by national and international literature (journals, books) and interviews with specialists. The HPV has a frequency between 36% and 74% among the population, and every day a huge number on any existing group is been diagnosed, is been described around 80 types. The HPV lesion related with bucal cavity and the periodontum are: papilloma, condyloma, focal epithelial hyperplasia, carcinoma verrugoso, leukoplakia, lichen planus, also has close relationship with HIV positive patiens. Among the periodontal treatments applied on this lesions are: Gingivectomy. Also, on this study a clinic case is reported, a nine years old male patient, assisted to the Periodontics Postgrade at the University of Zulia, School of Dentistry, having a previous history the presence of a oral lesion related with the HPV. Conclusions: so having this point on mind is important to identify these conditions to determine the right treatment plan and establish the sequence of the treatment chosen to improve the oral and periodontal health of the patient. Is important that the general dentist, the periodontist and the other specialties identify this pathologies and the consequences that might bring along if prevention is not done time, and always having the biosecurity norms present at the treatment time.


El propósito de esta revisión es describir los conocimientos actuales sobre el Virus Papiloma Humano (VPH) y su relación en la cavidad bucal y en el periodonto, soportado en una revisión bibliografica. Para ello se realizó una investigación descriptiva y documental principalmente con literatura nacional e internacional (revistas, libros) y entrevistas a especialistas en la materia. El VPH tiene una frecuencia entre 36% y el 74% de la población, y cada día se diagnostica un gran número en cualquier grupo etario, se describen alrededor de 80 tipos. Las lesiones del VPH relacionadas con la cavidad bucal y en el periodonto son: papiloma, condiloma acuminado, hiperplasia epitelial focal, carcinoma verrugoso, leucoplasia, liquen plano, además, tiene una estrecha relación con pacientes VIH positivos. Entre los tratamientos periodontales aplicados en estas lesiones se citan: la gingivectomía quirúrgica, electroquirúrgica, láser y quimioquirúrgica, siendo la mas utilizada la gingivectomía quirúrgica. Además, en el estudio se reporta un caso clínico de un paciente masculino, De 9 años de edad que asistió al área clínica del Postgrado de Periodoncia en la Facultad de Odontología de la Universidad del Zulia, teniendo como antecedentes la presencia de una lesión en boca relacionada con el Virus Papiloma Humano. De allí la importancia de identificar estas condiciones para determinar un correcto plan de tratamiento y establecer la secuencia del tratamiento elegido para mejorar la salud bucal y periodontal del paciente. Conclusión: Es importante que el Odontólogo General, el Periodoncista y los demás especialistas identifiquen estas patologías y las consecuencias que ocasiona si no se previene a tiempo, poniendo siempre en práctica las normas de bioseguridad al momento de trabajar.

4.
Acta odontol. venez ; 42(2): 73-79, ago. 2004.
Artigo em Espanhol | LILACS | ID: lil-394132

RESUMO

La historia clínica es fundamental en el manejo de cualquier tipo de pacinetes, los síntomas y signos que pueden sugerir enfermedad hemorrágica pueden ser de dos tipos: los que se ven más frecuentes en las alteraciones de los factores de coagulación y aquellos que son más comunes en trastornos de la hemostasia primaria, plaquetaria o vasculares y se conocen generalmente como púrpuras o síndrome purpúrico. Las petequias son pequeñas hemorragias capilares, usualmente puntiformes, son típicas en el síndrome purpúrico y suelen ser más intensas y confluentes en los sitios de presión. La equimosis es la infiltración en la piel o mucosas de la sangre extravasada (el típico moretón o cardenal), están usualmente asociadas a petequias en el síndrome purpúrico, pero pueden verse de buen tamaño, en los trastornos de coagulación y síndromes hiperfibrinolíticos. Los hematomas, colección de sangre extravasada en los músculos o tejidos profundos, son más frecuentes en los defectos del sistema de coagulación, como lo es también la hemartrosis, hemorragia intraarticular casi patognomónica de trastorno hereditario severo de la coagulación (hemofilia A y B). El sangramiento purpúrico se caracteriza por hemorragias mucocutáneas (petequia, equimosis, monorragias, hematura o sangramiento digestivo). Usualmente ellas son múltiples, y a veces aparecen después de injurias superficiales, el sangramiento comienza inmediatamente después de la ruptura vascular, todas estas manifestaciones clínicas son importantes que el odontólogo las reconozca con el fin de proporcionar un mejor tratamiento odontológico al paciente con trastornos hemorrágicos y evitar complicaciones no deseadas


Assuntos
Humanos , Masculino , Feminino , Anticoagulantes , Assistência Odontológica para Doentes Crônicos/métodos , Transtornos Hemorrágicos , Equimose , Fator de Ativação de Plaquetas/fisiologia , Hematoma , Hemofilia A , Púrpura , Transtornos Herdados da Coagulação Sanguínea/diagnóstico
5.
J Periodontol ; 73(10): 1177-83, 2002 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-12416776

RESUMO

BACKGROUND: The purpose of this study was to determine whether maternal periodontal disease (PD) could be associated with the nutritional condition of newborns. METHODS: After controlling for traditional risk factors for premature childbirth and low birth weight, 69 mothers were selected: 13 were periodontally healthy and 56 had varying stages of PD. They and their newborns formed the study population. PD presence and severity were clinically determined using Russell's periodontal index. The nutritional evaluation of the newborns was determined by Lubchenco's modified growth patterns. RESULTS: A decrease in the average newborn's weight and gestational age was observed as the mother's level of PD increased. Correlation analysis demonstrated a highly significant clinical relationship between more severe PD and lower birth weight (r = -0.49; P < 0.01); a highly significant relationship was also clinically demonstrated between increasing PD severity and decreasing gestational age of the newborn babies (r = -0.59; P < 0.01). There were significant differences in the weight and gestational age of the newborns of mothers with PD. CONCLUSIONS: These data suggest that PD in pregnant women could be a clinically significant risk factor for preterm deliveries and low birth weight. There was considerable variability in the results, and these preliminary findings need to be confirmed in larger studies.


Assuntos
Infecções por Bactérias Gram-Negativas , Doenças Periodontais , Complicações Infecciosas na Gravidez , Fenômenos Fisiológicos da Nutrição Pré-Natal , Adolescente , Adulto , Análise de Variância , Peso ao Nascer , Estudos de Casos e Controles , Feminino , Idade Gestacional , Infecções por Bactérias Gram-Negativas/complicações , Humanos , Recém-Nascido de Baixo Peso , Recém-Nascido , Idade Materna , Trabalho de Parto Prematuro/etiologia , Doenças Periodontais/complicações , Índice Periodontal , Gravidez , Análise de Regressão , Fatores de Risco , Estatísticas não Paramétricas
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