1.
Org Lett
; 7(26): 5797-800, 2005 Dec 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16354069
RESUMO
[reaction: see text] The copper reagent arising from an optically pure propargylic oxazolidinone was found to react regio- and diastereoselectively with aldehydes, leading, in a one-pot procedure, to the anti homopropargylic amino alcohols derivatives in good yields.
2.
Org Lett
; 5(14): 2567-9, 2003 Jul 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12841782
RESUMO
[reaction: see text] Anti alpha-amino-homopropargylic alcohols are prepared by addition of metallated propargylic amines to aldehydes. Among the four organometallic (LI, Zn, Ti, Cu) derivatives used, the most effective are the copper reagents.