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J Pediatr Surg ; 50(8): 1264-8, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25783296

RESUMO

BACKGROUND: The ingestion of caustic substances remains an important public health issue worldwide. Children represent 80% of the ingestion injury population globally. Accidental alkaline material accounts for most caustic ingestions. There is no conclusive evidence of tissue damage and stricture protection of a nasogastric-tube with a solid dilator in the literature, therefore it was hypothesized that early intraesophageal tube placement does not cause additional histopathologic damage and prevents strictures. METHODS: An exploratory study on experimental caustic esophageal burns in a rabbit model was designed. In the treated group a silicone tube was placed immediately after causing the burns, while the untreated group followed the natural course of the burn. On the twenty-secondday, an esophagectomy was performed on all animals for microscopic (Histopathologic Damage Score and Stenosis Index) and macroscopic analysis. RESULTS: Forty animals were randomly divided into two groups. The Histopathologic Damage Score was 3.7±1.1 in the treated group versus 3.9±1.2 in the untreated group (p=.9690). The Stenosis Index was 0.6±0.1 in treated rabbits versus 2.3±0.2 in untreated (p<.0001). CONCLUSION: The early placement of an intraesophageal tube with solid dilator prevents stenosis formation and does not produce greater tissue damage.


Assuntos
Queimaduras Químicas/terapia , Cáusticos/toxicidade , Dilatação/instrumentação , Estenose Esofágica/prevenção & controle , Esôfago/lesões , Intubação Gastrointestinal , Animais , Queimaduras Químicas/etiologia , Estenose Esofágica/induzido quimicamente , Humanos , Intubação Gastrointestinal/instrumentação , Intubação Gastrointestinal/métodos , Masculino , Coelhos , Distribuição Aleatória
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