Influence of route of administration on the plasma concentrations of ivermectin in reindeer.

The concentration of ivermectin in the plasma of reindeer was measured after it was administered either topically as a pour-on preparation at 500 micrograms kg-1 bodyweight at different seasons to animals of different ages, or after subcutaneous and oral doses of 200 micrograms kg-1 bodyweight. The plasma concentrations of ivermectin were highest and least variable after it was administered subcutaneously.

A field evaluation of treatment with febantel for the control of Toxocara canis in pups.

The faecal egg count depression (FECD) of febantel (Rintal vet. 100 mg tablets, Bayer AG, Veterinär-Bereich, Leverkusen), against Toxocara canis was tested in suckling pups treated at 2 weeks of age. The dose rate was 30 mg kg-1 body weight given orally, once every 12 h, three times. The effect of a further treatment of 6- and 12-week-old pups on excreted eggs was also evaluated. The FECD of 6-week-old pups was 100%. However, some of the 12- and 17-week-old pups had low eggs per gram (epg) values indicating that shorter intervals between the treatments should have been used in order to minimize the risk of spreading T. canis eggs. The control pups of the first treatment group were untreated litter mates. They were treated when 4 weeks old and then followed a similar regimen to the experimental animals. At 6 weeks of age, their FECD was 100%, but low epg values were observed among 12- and 17-week-old pups, similar to the test group.