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1.
Pan Afr Med J ; 43: 33, 2022.
Artigo em Francês | MEDLINE | ID: mdl-36505021

RESUMO

Prostate lymphomas (LP) are rare, fewer than 300 cases have been reported in the literature. Each time they are a diagnostic surprise as is the case with our study that is typical, didactic and reports the thirteenth case of prostatic lymphoma in the marginal zone. The study involved a 65-year-old patient, with no particular previous history who presented with signs of prostatism lasting for 4 months, aggravated by the occurrence of acute urinary retention. The diagnosis of benign prostatic hyperplasia with normal prostate-specific antigen (PSA) level was easily made and the patient underwent transurethral resection. To our surprise, the histological study revealed a massive infiltration of prostatic tissue by a non-Hodgkin lymphoma (NHL), marginal zone lymphoma (MZL) subtype. According to Steuter, it was classified as prostatic lymphoma stage IVB with leukemic transformation. The patient has experienced remission for 18 months with normalization of LDH after R-chop therapy. Although rare, these sites of occurrence should be suspected, LDH assay should be systematic in patients with prostatic signs and normal PSA levels. Prognosis is variable, according to age, histologic type and evolutionary stage, however, the median overall survival is identical for primary and secondary forms.


Assuntos
Linfoma de Zona Marginal Tipo Células B , Neoplasias da Próstata , Retenção Urinária , Masculino , Humanos , Idoso , Retenção Urinária/etiologia , Neoplasias da Próstata/diagnóstico , Antígeno Prostático Específico , Próstata
2.
Pan Afr Med J ; 43: 8, 2022.
Artigo em Francês | MEDLINE | ID: mdl-36284883

RESUMO

Pleuropulmonary blastoma is a rare intrathoracic tumor in children. It is associated with poor prognosis and diagnosis is based on histological examination. We conducted a didactic study involving a 3-year-old child with severe acute respiratory distress associated with hemothorax; radiological and thoracoscopic examination suggested malignant pleuropulmonary process. Anatomopathological examination with radio-clinical comparison allowed for the diagnosis of solid-cystic pleuropulmonary blastoma type II. Unfortunately, given the severity of the clinical features, the child died within a few weeks due to multiple organ failure. Pathologist experience is very important to recognize the disease and to start adequate treatment as soon as possible. This allows for a tumor regression rate up to 90% after neoadjuvant treatment and a 5-year survival rate of at least 53% for aggressive forms: solid and solido-cystic tumors.


Assuntos
Neoplasias Pulmonares , Blastoma Pulmonar , Humanos , Pré-Escolar , Neoplasias Pulmonares/patologia , Blastoma Pulmonar/diagnóstico , Blastoma Pulmonar/patologia , Terapia Neoadjuvante , Radiografia
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