[The age-related changes in the antioxidant system enzymes of the erythroid cells of swine at the early stages of postnatal development]. / Vikovi zminy aktyvnosti fermentiv antyoksydantnoï systemy v erytroïdnykh klitynakh svynei na rannikh stadiiakh postnatal'noho rozvytku.

The age changes of energy metabolism and antioxidative system enzymes activity in "young", "mature" and "old" erythroid cells of 0-, 1-, 3-, 5-, 10-days old piglets were studied. The essential increase of superoxide dismutase and glutathione peroxidase activities in pig erythrocytes during three days of postnatal life was established. The rise of glucose-6-phosphate dehydrogenase and NADPH-dependent glutathione reductase activities was observed in piglets erythrocytes in the period from 5 to 10 days after birth. The discovered changes of enzymatic activity were particularly characteristic of the "young" cells. It is supposed that this mechanism is essential in erythrocyte membrane structures stabilization in the period of early postnatal adaptation of animals.

[Activity of enzymes of glycolysis in pig erythrocytes in the neonatal period]. / Aktyvnist' deiakykh fermentiv hlikolizu erytrotsytiv porosiat u neonatal'nomu periodi.

The age changes of 2,3-DPG concentration, 2,3-diphosphoglycerate mutase, hexokinase and pyruvate kinase activities in pigs erythroid cells during the first 10 days after birth have been investigated for study of the mechanism of blood oxygen-transport function regulation at the early stages of postnatal adaptation. It was established, that there are age peculiarities in young, mature and old erythrocytes metabolism in piglets during the transition to postnatal development. It was shown that the rise of 2,3-DPG, the allosteric effector of hemoglobin oxygen affinity level, is due to the increased activities of 2,3-diphosphoglycerate mutase and hexokinase after birth, that is particularly characteristic of the young pigs erythrocytes.