RESUMO
The article is based on the data obtained in the result of examination of 53 wounded with closed cranial injuries (slight and middle gravity cases), and 34 wounded with spine injuries, but without spinal marrow traumas. The activity of fibroblasts of spinal marrow was studied, as well as the functional activity of peripheral blood monocytes during a ten-day posttraumatic period. It was found out that patients had refractory anemia with a diminishing number of erythroid cells, and also initial infectious complications, such as pneumonia or wound suppuration.
Assuntos
Militares , Crânio/lesões , Traumatismos da Coluna Vertebral/cirurgia , Medula Óssea/imunologia , Concussão Encefálica/complicações , Concussão Encefálica/reabilitação , Concussão Encefálica/cirurgia , Fibroblastos/imunologia , Humanos , Monócitos/imunologia , Federação Russa , Crânio/cirurgia , Traumatismos da Coluna Vertebral/complicações , Traumatismos da Coluna Vertebral/reabilitação , Fatores de TempoRESUMO
Under study was functional activity of stromal (fibroblast) and granulo-monocytic cells-precursors in bone marrow cultures of 32 patients with acute pyodestructive diseases of the lungs. The disturbance of functional activity of cells-precursors of granulo-monocytopoiesis and stromal cells-precursors responsible for regulation of hemopoiesis was established which makes for the development of leukemoid reactions and anemia in patients with acute pyo-destructive diseases of the lungs.
Assuntos
Granulócitos/fisiologia , Hematopoese/fisiologia , Células-Tronco Hematopoéticas/fisiologia , Abscesso Pulmonar/sangue , Pulmão/patologia , Monócitos/fisiologia , Adolescente , Adulto , Idoso , Ensaio de Unidades Formadoras de Colônias , Feminino , Gangrena , Granulócitos/patologia , Células-Tronco Hematopoéticas/patologia , Humanos , Técnicas In Vitro , Masculino , Pessoa de Meia-Idade , Monócitos/patologiaRESUMO
Antiviral cellular resistance was studied in 32 patients with acute purulent-destructive pulmonary diseases and in 46 normal subjects by determination of monocytes and lymphocytes containing viral inclusions and the coefficient of their viral affection. Parameters of humoral activity and functional monocyte activity were also studied. It has been established that these diseases are attended by the affection of immunocompetent cells which leads to the suppression of their functional activity to reduce anti-infectious cellular defence. Development of an abscess and gangrene in the lung is being investigated taking into consideration not only changes in the quantity of the immunocompetent cells but also the dependence on the degree of their functional activity.