Guideline-Driven Care Improves Outcomes in Patients with Traumatic Rib Fractures.

There is no established national standard for rib fracture management. A clinical practice guideline (CPG) for rib fractures, including monitoring of pulmonary function, early initiation of aggressive loco-regional analgesia, and early identification of deteriorating respiratory function, was implemented in 2013. The objective of the study was to evaluate the effect of the CPG on hospital length of stay. Hospital length of stay (LOS) was compared for adult patients admitted to the hospital with rib fracture(s) two years before and two years after CPG implementation. A separate analysis was done for the patients admitted to the intensive care unit (ICU). Over the 48-month study period, 571 patients met inclusion criteria for the study. Pre-CPG and CPG study groups were well matched with few differences. Multivariable regression did not demonstrate a difference in LOS (B = -0.838; P = 0.095) in the total study cohort. In the ICU cohort (n = 274), patients in the CPG group were older (57 vs 52 years; P = 0.023) and had more rib fractures (4 vs 3; P = 0.003). Multivariable regression identified a significant decrease in LOS for those patients admitted in the CPG period (B = -2.29; P = 0.019). Despite being significantly older with more rib fractures in the ICU cohort, patients admitted after implementation of the CPG had a significantly reduced LOS on multivariable analysis, reducing LOS by over two days. This structured intervention can limit narcotic usage, improve pulmonary function, and decrease LOS in the most injured patients with chest trauma.

Off-pump versus on-pump coronary artery bypass surgery: does the pump influence outcome?

BACKGROUND: This study assessed hospitalization outcome differences for patients undergoing off-pump coronary artery bypass (OPCAB) grafting compared with patients having coronary artery bypass grafting with cardiopulmonary bypass. STUDY DESIGN: We conducted a nested case-control study from an 8-year, hospitalization cohort (n = 7,905) in which the data were collected prospectively. Inclusion criteria included a coronary artery bypass graft only and age greater than 18 years. Cases were patients undergoing OPCAB (n = 360) and controls were patients undergoing coronary artery bypass grafting with cardiopulmonary bypass (n = 1,080). Cases were matched to controls 1:3 on five variables: age (+/- 3 years), gender, diabetes, New York Heart Association Functional Classification, and surgical year (+/- 3 years). The 13 outcomes of interest were mortality, length of hospitalization, ICU length of stay, return to ICU, ventilator time, intraoperative complications, pulmonary complications, neurologic complications, renal complications, gastrointestinal complications, sternal wound infections, highest postoperative creatine kinase level, and units of blood products given during the procedure. Using logistic regression we controlled for eight confounding variables. RESULTS: Patients undergoing OPCAB had a significantly shorter length of hospitalization (relative risk [RR] = 0.95; 95% CI, 0.91-0.99%), fewer pulmonary complications (RR = 0.45; 95% CI, 0.22-0.88%), fewer intraoperative complications (RR = 0.04; 95% CI, 0.0048-0.31%) fewer blood product units given (RR = 0.31; 95% CI, 0.14-0.42%) and lower postoperative creatine kinase (RR = 0.99; 95% CI, 0.98-0.99%). There were no considerable differences for the remaining nine outcomes, including mortality and neurologic complications. CONCLUSIONS: Patients undergoing OPCAB had a considerably shorter length of hospitalization, had fewer pulmonary and intraoperative complications, and received a lower volume of blood products.