Trago accesorio: una clave para eldiagnóstico de anomalías sindrómicas / Accessory tragus: a clue to the diagnosis of syndromic anomalies

El trago accesorio es una malformación congénita del oído externo que puede asociarse con otras anomalías del primer y segundo arcos branquiales.Presentamos un caso de trago accesorio unilateral, localizado en la región preauricular en una niña de 12 años sin historia familiar de malformacionesdel desarrollo. Describimos el desarrollo embriológico, la clínica y las características histopatológicas del caso, remarcando la posible asociación conotras malformaciones de los arcos braquiales (AU)

Accessory tragus is a congenital malformation of the external ear that could be associated with other abnormalities of the first and second branchialarch. A case of a unilateral accessory tragus located in the preauricular region in a 12-year-old girl with no family history of developmental malformationsis reported.The clinical characteristics, embryologic development and histopathologic features are described. We emphasize the possible association with othermalformations of brachial archs (AU)

Solitary fibrous tumor arising in the fallopian tube.

BACKGROUND: Solitary fibrous tumor (SFT) is an uncommon neoplasm that usually arises in the pleura. Although this tumor has been described at other sites, in the female genital tract it is extremely uncommon. CASE: We present a case of solitary fibrous tumor arising in the fallopian tube. A 32-year-old woman who presented with acute flank pain had a presumptive diagnosis of leiomyoma of the fallopian tube after abdominopelvic ultrasound. The adnexal mass was excised laparoscopically. Histologic examination showed the characteristic features of a solitary fibrous tumor. CONCLUSION: Although rare, the diagnosis of solitary fibrous tumor can be considered in the differential diagnosis of adnexal masses.

Syncytial giant cell component. Review of 55 renal cell carcinomas.

Different types of multinucleated giant cells (MGC) have been documented in tumors with osteoclast-like appearance, with trophoblastic differentiation or as tumoral malignant giant cells. A new variety of MGC has been described in renal cell carcinoma. In order to study the frequency, nature and significance of this cellular type, we have reviewed our files. To assess the presence, nature and significance of these MGC in renal cell carcinomas and associated histologic subtype. To review all malignant renal tumors diagnosed in the last 5 years in our hospital and to carry out a morphologic and immunohistochemical study in renal cell carcinomas with syncytial type MGC. 55 renal cell carcinomas were reviewed. Clear cell (conventional) renal cell carcinoma was the most common type encountered (40 cases); two of these cases showed syncytial type MGC and low grade malignancy. Microscopically the MGC contained from 5 to 40 nuclei. Immunohistochemically, mononucleated and multinucleated cells were positive for cytokeratin CAM 5.2, cytokeratin AE1/AE3 and weakly positive for vimentin. Histiocytic, muscular, neural markers, beta-HCG and alpha-fetoprotein were negative. The presence of syncytial type MGC in renal cell carcinomas is an exceptional event. Among 55 renal cell carcinomas we found two cases, both of which were of clear cell subtype and low grade malignancy. The MGC proved positive for epithelial markers and probably are the result of mononucleated tumoral cell fusion. We are unaware of the impact of this MGC in the outcome of patients; such cells appear in low grade carcinomas and do not seem to be of dismal prognosis.